Intracolonic release of nitric oxide during trinitrobenzene sulfonic acid rat colitis

Digestive Diseases and Sciences

Volumn 42, Issue 12, 1997, Pages 2606-2611

  Ferretti, Maurizio ^b   Gionchetti, Paolo ^a   Rizzello, Fernando ^b   Venturi, Alessandro ^b   Stella, Patrizia ^b   Corti, Fabrizio ^b   Mizrahi, Jaques ^b   Miglioli, Mario ^b   Campieri, Massimo ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b NONE

Author keywords

Leukotrienes; Nitric oxide; Rat TNB colitis; Rectal dialysis

Indexed keywords

LEUKOTRIENE B4; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; TRINITROBENZENESULFONIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; COLITIS; COLON; DISEASE MODELS, ANIMAL; LEUKOTRIENE B4; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; TRINITROBENZENESULFONIC ACID;

EID: 0031427285     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018897519880     Document Type: Article

References (40)

1. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142, 1991
2. Stuehr DJ, Marlietta MA: Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 82:7738, 1985
3. Bredt DS, Hwang PM, Glatt CE, Lowestein C, Reed RR, Snyder SH: Cloned and expressed nitric oxide synthase structurally resemble cytochrome P450 reductase. Nature 351:714-718, 1991
4. Nakane M, Schmidt HHHW, Pollock JS, Forstermann U, Murad F: Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. FEBS Lett 316:175-180, 1993
5. Lamas S, Marsden PA, Li GK, Tempst P, Michel T: Endothelial nitric oxide synthase: Molecular cloning and characterization of distinct constitutive enzyme isoform. Proc Natl Acad Sci USA 89:6348-6352, 1992
6. Xie O, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, Nathan C: Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256:225-228, 1992
7. McCall TB, Boughton Smith NK, Palmer MJ, Whittle BJR, Moncada A: Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. Biochem J 261:295-296, 1989
8. Hibbs JB Jr, Taintor RR, Vavrin Z, Rachlin EM. Nitric oxide: A cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun 157:87-94, 1988
9. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial cell injury from nitric oxide. Proc Natl Acad Sci USA 87:1620-1624, 1990
10. Nussler AK, Di Silvio M, Billiar TR, Hoffman RA, Geller DA, Selby R, Madariaga J, Simmons RL: Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokine and endotoxin. J Exp Med 176:261-264, 1992
11. Nunokawa Y, Ishida N, Tanaka S: Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem Biophys Res Commun 181:89-94, 1993
12. Calver A, Coller J, Vallance P: Nitric oxide and cardiovascular control. Exp Physiol 78:303-326, 1993
13. Sessa WC, Barber CM, Lynch KR: Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytoslic protein. Circ Res 72:921-924, 1993
14. Ignarro LJ: Signal transduction mechanism involving nitric oxide. Biochem Pharmacol 41:485-490, 1991
15. Synder SH, Bredt DS: Nitric oxide as a neuronal messenger. TIPS 12:125-128, 1991
16. Synder SH: Nitric oxide: First in a new class of neurotransmitters? Science 257:494-496, 1992
17. Sanders KM, Ward SM: Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission. Am J Physiol 262:G379-G392, 1992
18. Boughton NK, Evans SM, Laszio F, Whittle BJR, Moncada S: The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. Br J Pharmacol 110:1189-1195, 1993
19. Boughton Smith NK, Evans SM, Whittle BRJ: Characterization of nitric oxide synthase activity in the rat colonic mucosa and muscle after endotoxin and in a model of colitis. Agents Actions 41:223-225, 1994
20. Miller MJS, Sadowska-Krowicka A, Chontinaruemol S, Kakkis JL, Clarke DA: Amelioration of chronic ileitis by nitric oxide synthase inhibition. J Pharmacol Exp Ther 264:11-16, 1993
21. Rachmilewitz D, Stamler JS, Karmeli F: Peroxynitrite-induced rat colitis - a new model of colonic inflammation. Gastroenterology 105:1681-1688, 1993
22. Rachmilewitz D, Karmeli F, Okon E, Bursztyn M: Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 36:247-255, 1995
23. Boughton-Smith NK, Evans SM, Hawkey CJ: Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet 342:338-340, 1993
24. Mourelle M, Caellas F, Guarner F, Malagelada JR: Toxic megacolon in patients with chronic ulcerative colitis may be due to induction of nitric oxide synthase. Gastroenterology 104:A749, 1993
25. Reynolds PD, Middleton SJ, Hunter P: High expression of iNOS in colonic mucosa in ulcerative colitis. Gut 36:A56, 1995
26. Lundberg JON, Hellstrom PM, Lundberg JM, Alving K: Greatly increase luminal nitric oxide in ulcerative colitis. Lancet 344:1673-1674, 1994
27. Middleton SJ, Shorthouse M, Hunter JO: Increased nitric oxide synthesis in ulcerative colitis. Lancet 341:465-466, 1993
28. Trann DD, Visser JJ, Pool MO: Enhanced systemic nitric oxide production in inflammatory bowel disease. Lancet 341:1150, 1993
29. Rachmilewitz D, Stamler JS, Bachwich D, Karmeli F, Acxerman Z, Podolsky DK: Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Gut 36:718-723, 1995
30. Boughton-Smith NK: Pathological and therapeutic implication for nitric oxide in inflammatory bowel disease. J R Soc Med 87:312-313, 1994
31. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL: Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 96:795-803, 1989
32. Vilaseca J, Salas A, Guarner F, Rodrigues R and Malagelada JR: Participation of thromboxane and other eicosanoids synthesis in the course of experimental inflammatory colitis. Gastroenterology 98:269-277, 1990
33. 2 concentration determined by equilibrium in vivo dialysis of faeces in patients with ulcerative colitis and healthy controls. Gut 25:1271-1278, 1984
34. Bradley PP, Priebat DA, Christensen RD: Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78:206-209, 1982
35. Leunberger UR, Gauch R, Baumgartner E: Determination of nitrate and bromide in foodstuff by HPLC. J Chromatogr 202:461-465, 1980
36. Corti F, Hua L, Passaro A: NO release from nitrocompounds investigated by spectrophotometric and HPLC analysis. Pharmacol Res 26(1):247, 1992
37. Bredt DS, Snyder SH: Isolation of nitric oxide synthase, a calmomodulin requiring enzyme. Proc Natl Acad Sci USA 87:682-685, 1990
38. Bradford MM: A rapid and sensitive method for the quantification of protein dye binding. Anal Biochem 72:248-254, 1976
39. Wallace JL, McNaughton WK, Morris GP, Beck PL: Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease. Gastroenterology 96:29-36, 1989
40. Roediger WEW, Lawson MJ, Radcliffe BC: Nitrite from inflammatory cells - a cancer risk factor in ulcerative colitis? Dis Colon Rectum 33:1034-1036, 1990