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Volumn 3, Issue 12 I, 1997, Pages 2393-2398

Pharmacokinetics of 3-methyl-(triazen-1-yl)imidazole-4-carboximide following administration of temozolomide to patients with advanced cancer

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYL(TRIAZEN 1 YL)IMIDAZOLE 4 CARBOXIMIDE; DRUG METABOLITE; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

EID: 0031426782     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (67)

References (15)
  • 1
    • 0023605735 scopus 로고
    • Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine
    • Stevens, M. F. G., Hickman, J. A., Langdon, S. P., Chubb, D., Vickers, L., Stone, R., Baig, G., Goddard, C., Gibson, N. W., Slack, J. A., Newton, C., Lunt, E., Fizames, C., and Lavelle, F. Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine. Cancer Res., 47: 5846-5852, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 5846-5852
    • Stevens, M.F.G.1    Hickman, J.A.2    Langdon, S.P.3    Chubb, D.4    Vickers, L.5    Stone, R.6    Baig, G.7    Goddard, C.8    Gibson, N.W.9    Slack, J.A.10    Newton, C.11    Lunt, E.12    Fizames, C.13    Lavelle, F.14
  • 2
    • 0026029701 scopus 로고
    • Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine, prodrugs of 3-methyl-(triazen-1-yl)imidazole-4-carboxamide
    • Tsang, L. L. H., Quarterman, C. P., Gescher, A., and Slack, J. A. Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine, prodrugs of 3-methyl-(triazen-1-yl)imidazole-4-carboxamide. Cancer Chemother. Pharmacol., 27: 342-346, 1991.
    • (1991) Cancer Chemother. Pharmacol. , vol.27 , pp. 342-346
    • Tsang, L.L.H.1    Quarterman, C.P.2    Gescher, A.3    Slack, J.A.4
  • 6
    • 0016475690 scopus 로고
    • Effects of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (NSC-407347), an alkylating agent derived from 5-(3,3-dimethyl-1-trizeno)imidazole-4-carboxamide (NSC-45388)
    • Mizuno, N. S., Decker, R. W., and Zakis, B. Effects of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (NSC-407347), an alkylating agent derived from 5-(3,3-dimethyl-1-trizeno)imidazole-4-carboxamide (NSC-45388). Biochem. Pharmacol., 24: 615-619, 1975.
    • (1975) Biochem. Pharmacol. , vol.24 , pp. 615-619
    • Mizuno, N.S.1    Decker, R.W.2    Zakis, B.3
  • 9
    • 0028174027 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide
    • 6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide. Br. J. Cancer, 69: 452-456, 1994.
    • (1994) Br. J. Cancer , vol.69 , pp. 452-456
    • Lee, S.M.1    Thatcher, N.2    Crowther, D.3    Margison, G.P.4
  • 10
    • 0027477913 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity and sensitivity of human tumor cells and xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea
    • 6-alkylguanine-DNA alkyltransferase activity and sensitivity of human tumor cells and xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Chemother. Pharmacol., 32: 59-63, 1993.
    • (1993) Cancer Chemother. Pharmacol. , vol.32 , pp. 59-63
    • Mitchell, R.B.1    Dolan, M.E.2
  • 11
  • 12
    • 0026616913 scopus 로고
    • 6-methylguanine on DNA damage and cytotoxicity of temozolomide in L1210 mouse leukemia sensitive and resistant to chloroethylnitrosoureas
    • 6-methylguanine on DNA damage and cytotoxicity of temozolomide in L1210 mouse leukemia sensitive and resistant to chloroethylnitrosoureas. Anti-Cancer Drugs, 3: 401-405, 1992.
    • (1992) Anti-Cancer Drugs , vol.3 , pp. 401-405
    • Taverna, P.1    Catapano, C.V.2    Citti, L.3    Bonfanti, M.4    D'Incalci, M.5
  • 14
    • 0025096409 scopus 로고
    • Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity
    • Tsang, L. L. H., Farmer, P. B., Gescher, A., and Slack, J. A. Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity. Cancer Chemother. Pharmacol., 26: 429-436, 1990.
    • (1990) Cancer Chemother. Pharmacol. , vol.26 , pp. 429-436
    • Tsang, L.L.H.1    Farmer, P.B.2    Gescher, A.3    Slack, J.A.4
  • 15
    • 0028133013 scopus 로고
    • NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA
    • Denny, B. J., Wheelhouse, R. T., Stevens, M. F. G., Tsang, L. L. H., and Slack, J. A. NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA. Biochemistry, 33: 9045-9051, 1994.
    • (1994) Biochemistry , vol.33 , pp. 9045-9051
    • Denny, B.J.1    Wheelhouse, R.T.2    Stevens, M.F.G.3    Tsang, L.L.H.4    Slack, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.