Evaluation of the serum-free medium MDSS2 for the production of poliovirus on Vero cells in bioreactors

Cytotechnology

Volumn 25, Issue 1-3, 1997, Pages 35-44

  Merten, O W ^a,b   Wu, R ^a   Couve E ^a   Crainic, R ^a  

^a INSTITUT PASTEUR   (France)

^b GÉNÉTHON   (France)

Author keywords

Optimisation; Perfusion culture; Poliovirus Sabin 1; Serum free medium; Vero cells

Indexed keywords

EID: 0031426290     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1007999313566     Document Type: Article

References (25)

1. Bjare U and Räbb I (1985) Serum free cultivation of lymphoid cells for virus and interferon production. Dev Biol Standard 60, 349-354.
2. Büntemeyer H (1988) Entwicklung eines Perfusionssystems zur kontinuierlichen Kultivierung tierischer Zellen in Suspension. Ph. D. Thesis, Universität Hannover/D.
3. Cinatl J Jr, Cinatl J, Rabenau H, Rapp J, Kornhuber B and Doerr H-W (1993) Protein-free culture of Vero cells: A substrate for replication of human pathogenic viruses. Cell Biol Int 17, 885-895.
4. Croughan MS and Wang DIC (1991) Hydrodynamic effects on animal cells in microcarrier bioreactors. In: Animal Cell Bioreactors, eds. Ho, SC and Wang, DIC, pp. 213-249, Butterworth-Heinemann, Boston, USA.
5. Duchene M, Peetermans J, D'Hondt E, Harford N, Fabry L and Stephenne J (1990) Production of poliovirus vaccines: past, present, and future. Viral Immunol 3, 243-272.
6. Enders JF, Weller TH and Robbins FC (1949) Cultivation of Lansing strain of poliomyelitits virus in culture of various human embryonic tissues. Science 109, 85-87.
7. Fabry L, Baijot B, D'Hondt E and Duchene M (1989) High density microcarrier cell culture for viral vaccine production. In: Advances in Animal Cell Biology and Technology for Bioprocesses, eds. Spier RE, Griffiths JB, Stephenne J and Crooy PJ, pp. 361-365, Butterworths, Sevenoaks/UK.
8. Furusawa E and Cutting W (1962) Inhibitory effect of ammonium sulfate on Columbia SK virus propagation in mouse ascites tumor cells in vitro. Proc Soc Exptl Biol Med 111, 71-75.
9. Hayter PM, Curling EMA, Baines AJ, Jenkins N, Salmon I, Strange PG, Tong JM and Bull AT (1991) Glucose-limited chemostat culture of Chinese hamster ovary cells producing recombinant human interferon-gamma. Biotechnol Bioeng 39, 327-335.
10. Hu WS, Meier J and Wang DIC (1985) A mechanistic analysis of the inoculum requirement for the cultivation of mammalian cells on microcarriers. Biotechnol Bioeng 27, 585-595.
11. Ito Y, Kimura Y, Nagata I and Kunii A(1974) Effects of L-glutamine deprivation of growth of HVJ (Sendai virus) in BHK cells. J Virol 13, 557-566.
12. Jensen EM and Liu OC (1961) Studies of inhibitory effect of ammonium ions in several virus-tissue culture systems. Proc Soc Exptl Biol Med 107, 834-838.
13. Merten O-W, Hannoun C, Manuguerra J-C, Ventre F and Petres S (1996) Production of influenza virus in cell cultures for vaccine preparation. In: Novel Strategies in Design and Production of Vaccines, eds. Cohen S and Shafferman A, pp. 141-151. Plenum Press, New York/USA.
14. Merten O-W, Kierulff KV, Castignolles N and Perrin P (1994) Evaluation of the new serum-free medium (MDSS2) for the production of different biologicals: use of various cell lines. Cytotechnology 14, 47-59.
15. Merten O-W, Petres S and Couvé E (1995) A simple serum-free freezing medium for serum-free cultured cells. Biologicals 23, 185-189.
16. Montagnon BJ, Fanget B and Nicolas AJ (1981) The large scale cultivation of Vero cells in microcarrier culture for vaccine production preliminary results for killed poliovirus vaccine. Dev. biol. Standard. 47, 55-64.
17. Montagnon BJ, Vincent-Falquet JC and Fanget B (1984) Thousand litre scale microcarrier culture of Vero cells for killed polio virus vaccine. Promising results. Dev Biol Standard 55, 37-42.
18. Morgeaux S, Tordo N, Gontier C and Perrin P (1993) β-propiolactone treatment impairs the biological activity of residual DNA from BHK-21 cells infected with rabies virus. Vaccine 11, 82-90.
19. Perrin P, Madhusudana S, Gontier-Jallet C, Petres S, Tordo N and Merten O-W (1995) An experimental rabies vaccine produced with a new BHK-21 suspension culture process: use of serum-free medium and perfusion-reactor system. Vaccine 13, 1244-1250.
20. Smith BJ and Panico KA (1985) Automated analysis of ophtalaldehyde derivates of amino acids in physiological fluids by reversed HPLC. J Liquid Chromatogr 8, 1783-1795.
21. Tomei LD and Issel CJ (1975) Growth and Immunogenicity of foot and mouth disease virus in bady hamster kidney cells adapted to and continuously grown in a serum-free chemically defined media. Biotechnol Bioeng 17, 765-778.
22. van Wezel AL (1967) Growth of cell strains on microcarriers in homogeneous culture. Nature 216, 64-65.
23. WHO (1988) Expanded programme on immunization. Global eradication of poliomyelitis by the year 2000. Weekly Epidemiological Record 63, 161-162.
24. WHO (1990) Manual for the virological investigation of poliomyelitis. In: Global Poliomyelitis Eradication by the Year 2000, pp. 37-40.
25. Zwartouw HT and Algar DJ (1968) Growth of high-titre Semliki Forest Virus in concentrated suspensions of chick embryo cells. J Gen Virol 2, 243-250.