Tetrahymena recovering from a heavy accumulation of a gold salt

Acta Protozoologica

Volumn 36, Issue 2, 1997, Pages 111-119

  Nilsson, Jytte R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Aurothiomalate; Cell recovery; Tetrahymena

Indexed keywords

TETRAHYMENA;

EID: 0031426085     PISSN: 00651583     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Basco J., Uzonyi I., Dezcö B. (1988) Determination of gold accumulation in human tissue caused by gold therapy using X-ray fluorescence analysis. Appl. Radiat. Isot. 39: 323-326
2. Biggs D.F., Boland D.M., Davis P, Wakaruk J. (1979) In vitro binding and pharmacokinetics of gold salts in plasma proteins and chelating agents. J. Rheumatol. (suppl. 5) 6: 68-73
3. Brady F.O. (1982) The physiological function of metallothionein. Trends. Biochem. Sci. 7: 143-145
4. Brown D.H., Smith W.E. (1980) The chemistry of the gold salts used in the treatment of rheumatoid arthritis. Chem. Soc. Rev. 9: 217-240
5. Butt T.R., Sternberg E.J., Mirabelli C.K., Crooke S.T. (1986) Regulation of metallothionein gene expression in mammalian cells by gold compounds. Mol. Pharmacol. 29: 204-210
6. Carter T.R. (1988) Intramammary lymph node gold deposits simulating microcalcifications on mammograms. Hum. Pathol. 19: 992-994
7. Cheatum D.E. (1996) How far can you go? Use of very low dosage of gold in patients with mucocutaneous reactions. J. Rheumatol. 23: 944
8. Ghadially F.N. (1979) The aurosome. J. Rheumatol. (suppl. 5) 6: 45-50
9. Graabæk P.M., Pedersen S.M. (1988) Effect of two gold compounds on lysosomes. Ann. Rheum. Dis. 47: 509-514
10. Grootveld M.C., Sadler P. (1983) Differences between the structure of the anti-arthritic gold drug "Myocrisin" in the solid state and in solution: a kinetic study of dissolution. J. Inorg. Biochem. 19: 51-64
11. Kassam Y.B., Kean W.F., Lock C.J.L., Buchanan W.W., Simons G.T., Harvey D.A. (1987) Variation in physical and biological properties of solid gold sodium thiomalate on dissolution: An electron microscopic and energy dispersive spectroscopic study. J. Reumatol. 14: 209-215
12. Klinkhoff A. V., Teufel A. (1995) How low can you go? Use of very low dosage of gold in patients with mucocutaneous reactions. J. Rheumatol. 22: 1657-1659
13. Lawson K.J., Danpure C.J., Fyfe D.A. (1977) The uptake and subcellular distribution of gold in liver cells after in vivo administration of sodium aurothiomalate. Biochem. Pharmacol. 26: 2417-2426
14. Lipsky P.E., Ugai K., Ziff M. (1979) Alterations in human monocyte structure and function induced by incubation with gold sodium thiomalate. J. Rheumatol. (suppl. 5) 6: 130-136
15. Mallya S.K., Van Wart H.E. (1989) Mechanism of inhibition of neutrophil collagenase by gold(I) chryso-therapeutic compounds. Interaction of a heavy metal binding site. J. Biol. Chem. 264: 1594-1601
16. Mehta S., Webb H.E. (1982) Lysosomal enzyme changes in macrophages from mice given myocrisin and infected with avirulent semliki forest virus. Br. J. exp. Path. 63: 443-446
17. Nakamura H., Igarashi M. (1977) Localization of gold in synovial membrane of rheumatoid arthritis treated with sodium aurothiomalate. Ann. Rheum. Dis. 36: 209-215
18. Nilsson J.R. (1981) On cell organelles in Tetrahymena. With special reference to mitochondria and peroxisomes. Carlsberg Res. Commun. 46: 279-304
19. Nilsson J.R. (1988) Cytotoxic effects of cisplatin, cisdichlorodiammineplatinum(II), on Tetrahymena. J. Cell Sci. 90: 707-716
20. Nilsson J.R. (1989) Tetrahymena in cytotoxicology: with special reference to effects of heavy metals and selected drugs. Eur. J. Protistol. 25: 2-25
21. Nilsson J.R. (1993) Effects of a gold salt and its intracellular distribution in Tetrahymena. Acta Protozool. 32: 141-150
22. Nilsson J.R. (1996) Effects of a bismuth salt on cell proliferation, endocytosis, and fine structure of Tetrahymena. Eur. J. Protistol. 32: 283-292
23. Pääkkö P., Antilla S., Sutinen S. (1984) Lysosomal gold accumulation in pulmonary macrophages. Ultrastruct. Pathol. 7: 289-294
24. Plesner P., Rasmussen L., Zeuthen E. (1964) Techniques used in the study of synchronous Tetrahymena. In: Synchrony in Cell Division and Growth (Ed. E. Zeuthen). Interscience, New York, 543-563
25. Sadler P.J. (1976) The biological chemistry of gold: a metal-drug and heavy-atom label with variable valency. Struct. Bonding (Berlin) 29: 171-215
26. Saito S., Kojima Y. (1996) Relative gold-binding capacity of metallothionein: studies in renal cytosols of gold-injected rats. Res. Commun. Mol. Pathol. Pharmcol. 92: 119-126
27. Schmitz G., Minkel D.T., Gingrich D., Shaw III C.F. (1980) The binding of gold(I) to metallothionein. J. Inorg. Biochem. 12: 293-306
28. Strunk S.W, Ziff M. (1970) Ultrastructural studies of the passage of gold thiomalate across the renal glomerular capillary wall. Arthritis and Rheumatism 13: 39-52
29. Vernon-Roberts B. (1979) Action of gold salts on the inflammatory response and inflammatory cell function. J. Rheumatol. (suppl. 5) 6: 120-129
30. Vernon-Roberts B., Doré J.L., Jessop J.D., Henderson W.J. (1976) Selective concentration and localization of gold in macrophages of synovial and other tissues during and after chrysotherapy in rheumatoid patients. Ann. Rheum. Dis. 35: 377-486
31. Weast R.C., ed. (1973) Handbook of Chemistry and Physics (53rd ed.). The Chemical Rubber Co.