Gene expression and protein deposition of major basement membrane components and TGF-β1 in human breast cancer

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4443-4449

  Nerlich, Andreas G ^a,d   Wiest, Irmgard ^a   Wagner, Evi ^b   Sauer, Ulrich ^b   Schleicher, Erwin D ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Klinikum Schwabing   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d Pathologisches Institut d Univ   (Germany)

Author keywords

Basement membrane; Collagen IV; Fibronectin; Invasive growth; Perlecan; Synthesis; TGF 1

Indexed keywords

COLLAGEN TYPE 4; CYTOKINE; FIBRONECTIN; LAMININ; MATRIX METALLOPROTEINASE; MESSENGER RNA; PERLECAN; PROTEOHEPARAN SULFATE; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BASEMENT MEMBRANE; BREAST CANCER; BREAST FIBROADENOMA; CANCER INVASION; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA SYNTHESIS;

ADULT; AGED; AGED, 80 AND OVER; BASEMENT MEMBRANE; BREAST; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; COLLAGEN; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER NEOPLASMS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROTEOGLYCANS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031425495     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Nerlich A, Haraida S, Hagedorn H, Wiest I, Schreiner M, Schleicher ED: Morphological aspects of basement membranes and their receptors in benign and malignant neoplasms. Int J Oncol 6: 1193-1202, 1995.
2. Nerlich A: Morphologie von Basalmembran- und assoziierten Matrixproteinen in normalem und pathologischem Gewebe. Fischer Verlag, Stuttgart New York 1995.
3. Albrechtsen R, Nielson M, Wewer U, Engvall E, Ruoslahti E: Basement membrane changes in breast cancer detected by immunohistochemical staining for laminin. Cancer Res 41: 5076-5081, 1981.
4. Gusterson BA, Warburton MJ, Mitchell D, Ellison N, Munro-Neville A, Rudland PS: Distribution of myoepithelial cells and basement membrane proteins in the normal breast and in benign and malignant breast disease. Cancer Res 42: 4763-4770, 1982.
5. Remberger K, Nerlich A: Diagnostischer Wert der Darstellung von Basalmembranproteinen in benignen und malignen Mammaveränderungen. Verh Dtsch Ges Pathol 69: 123-130, 1985.
6. Wetzels RHW, Holland R, van Haelst JGM, Lane B, Ramaekers FCS: Detection of basement membrane components and basal cell heratin 14 in noninvasive and invasive carcinomas of the breast. Am J Pathol 134: 571-579, 1989.
7. Frenette GP, Carey TE, Varani J, Schwartz DR, Fligel SEG, Ruddon RW, Peters BP: Biosynthesis and secretion of laminin and laminin-associated glycoproteins by nonmalignant and malignant human keratinocytes: Comparison of cell lines from primary and secondary tumors in the same patient. Cancer Res 48: 5193-5202, 1988.
8. Damjanov I, Damjanov N, Knowles BB, Engvall E: Origin of laminin in the extracellular matrix of human tumor xenografts in nude mice. Virchows Arch B49: 45-52, 1985.
9. Daher N, Abourachid H, Bove N, Petit J, Burtin P: Collagen IV staining pattern in bladder carcinomas: relationship to prognosis. Br J Cancer 55: 665-671, 1987.
10. Offerhaus GJA, Giardiello FM, Brujin JA, Stjinen T, Molyvas EN, Fleuren GJ: The value of immunohistochemistry for collagen IV expression in colorectal carcinomas. Cancer 67: 99-105, 1991.
11. Schapers RFM, Pauwels PE, Havenith MG, Smeets AWGB, van den Brandt PA, Bosman FT: Prognostic significance of type IV collagen and laminin immunoreactivity in urothelial carcinomas of the bladder. Cancer 66: 2583-2588, 1990.
12. Schleicher E, Wagner EM, Olgemöller B, Nerlich A, Gerbitz KD: Characterization and localisation of basement membrane associated heparan sulfate proteoglycan in human tissues. Lab Invest 61: 323-332, 1989.
13. Nerlich A, Schleicher E: Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions. Am J Pathol 139: 889-899, 1991.
14. Hsu SM, Raine L, Fanger A: A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radio immunoassay antibodies. Am J Clin Pathol 75: 734-739, 1981.
15. Ceol M, Nerlich A, Baggio B, Anglani F, Sauer U, Schleicher E, Gambaro G: Increased glomerular α1(IV) collagen expression and deposition in long-term diabetic rats is prevented by chronic glycosaminoglycan treatment. Lab Invest 74: 484-495, 1996.
16. Cordell JL, Falini B, Erber WN, Ghosh AH, Abdulaziz Z, MacDonald S, Pulford AF, Stein H, Mason DY: Immunoenzymtaic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase. J Histochem Cytochem 32: 219-225, 1984.
17. Barsky SH, Siegal GP, Jannotta F, Liotta LA: Loss of basement membrane components by invasive tumors but nor by their benign counterparts. Lab Invest 49: 140-147, 1983.
18. Soini Y, Hurskainen T, Höyhtyä M, Oikarinen A, Autio-Harmainen H: 72 kd and 92 kd type IV collagenase, type IV collagen and laminin mRNAs in breast cancer: A study by in situ hybridization. J Histochem Cytochem 42: 945-951, 1994.
19. Clavel C, Doco M, Lallemand A, Laurent M, Birembaut P: Detection by in situ hybridization of messenger RNAs of collagen types I and IV in murine mammary cancer. Int J Cancer 44: 548-553, 1989.
20. Soini Y, Pääkkö P, Autio-Harmainen H: Genes of laminin B1 chain, α1(IV) chain of type IV collagen and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas. Am J Pathol 142: 1622-1630, 1993.
21. Hewitt RE, Powe DG, Carter I, Turner DR, Price JE: Basement membrane collagen-IV synthesis in colorectal tumors. Int J Cancer 51: 530-536, 1992.
22. Soini Y, Autio-Harmainen H: Synthesis and degradation of basement membrane in benign and malignant salivary gland tumors. A study by in situ hybridization. J Pathol 170: 291-296, 1993.
23. Dubling EA, Barnes DM, Wang DY, King RJB, Levison DA: TGF alpha and TGF beta expression in mamary carcinomas. J Pathol 170: 15-22, 1993
24. Gorsch SM, Memoli VA, Stukel TA, Gold LI, Arrick BA: Immunohistochemical staining for transforming growth factor ß1 associates with disease progression in human breast cancer. Cancer Res 52: 6949-6952, 1992
25. Walker RA, Dearing SJ, Gallacher B: Relationship of transforming growth factor ß1 to extracellular matrix and stromal infiltration in invasive breast cancer. Br J Cancer 69: 1160-1165, 1994