메뉴 건너뛰기




Volumn 33, Issue 14, 1997, Pages 2418-2427

A pharmacokinetic and pharmacodynamic study in vivo of human HT29 tumours using 19F and 31P magnetic resonance spectroscopy

Author keywords

5 Fluorouracil; Human tumours; Interferon ; Pharmacokinetics; Phosphorus fluorine magnetic resonance spectroscopy

Indexed keywords

FLUOROURACIL;

EID: 0031424746     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(97)00336-5     Document Type: Article
Times cited : (30)

References (44)
  • 1
    • 0027980010 scopus 로고
    • Preclinical and clinical aspects of biomodulation of 5-fluorouracil
    • Sotos GA, Grogan L, Allegra C. Preclinical and clinical aspects of biomodulation of 5-fluorouracil. Cancer Treat Rev. 20:1994;11-49.
    • (1994) Cancer Treat Rev , vol.20 , pp. 11-49
    • Sotos, G.A.1    Grogan, L.2    Allegra, C.3
  • 2
    • 0026637845 scopus 로고
    • Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer HCT-8 sublines following exposure to two different clinically relevant dose schedules
    • Aschele C, Sobrero A, Faderan MA, Bertino JR. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer HCT-8 sublines following exposure to two different clinically relevant dose schedules. Cancer Res. 52:1992;1855-1864.
    • (1992) Cancer Res , vol.52 , pp. 1855-1864
    • Aschele, C.1    Sobrero, A.2    Faderan, M.A.3    Bertino, J.R.4
  • 3
    • 0022400840 scopus 로고
    • Enzymes of uracil catabolism in normal and neoplastic human tissues
    • Naguib FNM, el Kouni MH, Cha S. Enzymes of uracil catabolism in normal and neoplastic human tissues. Cancer Res. 45:1985;5405-5412.
    • (1985) Cancer Res , vol.45 , pp. 5405-5412
    • Naguib, F.N.M.1    El Kouni, M.H.2    Cha, S.3
  • 4
    • 0031014682 scopus 로고    scopus 로고
    • Thymidylate synthase inhibitors in cancer therapy: Direct and indirect inhibitors
    • Rustum YM, Harstrick A, Cao S, et al. Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors. J Clin Oncol 1997, 15, 389-400.
    • (1997) J Clin Oncol , vol.15 , pp. 389-400
    • Rustum, Y.M.1    Harstrick, A.2    Cao, S.3
  • 7
    • 0025921621 scopus 로고
    • 19F Magnetic resonance spectroscopy studies of the metabolism of 5-fluorouracil in murine RIF-1 tumours and liver
    • 19F Magnetic resonance spectroscopy studies of the metabolism of 5-fluorouracil in murine RIF-1 tumours and liver. Cancer Res. 51:1991;1384-1390.
    • (1991) Cancer Res , vol.51 , pp. 1384-1390
    • Sijens, P.E.1    Huang, Y.2    Baldwin, N.J.3    Ng, T.C.4
  • 9
    • 0024419144 scopus 로고
    • Prediction of 5-fluorouracil cytotoxicity towards the Walker carcinosarcoma using peak integrals of fluoronucleotides measured by MRS in vivo
    • McSheehy PMJ, Prior MJW, Griffiths JR. Prediction of 5-fluorouracil cytotoxicity towards the Walker carcinosarcoma using peak integrals of fluoronucleotides measured by MRS in vivo. Br J Cancer. 60:1989;303-309.
    • (1989) Br J Cancer , vol.60 , pp. 303-309
    • McSheehy, P.M.J.1    Prior, M.J.W.2    Griffiths, J.R.3
  • 12
    • 0027303708 scopus 로고
    • 19F magnetic resonance spectroscopy in patients with colorectal cancer: A pilot study
    • 19F magnetic resonance spectroscopy in patients with colorectal cancer: a pilot study. Ann Oncol 1993, 4, 597-602.
    • (1993) Ann Oncol , vol.4 , pp. 597-602
    • Findlay, M.P.N.1    Leach, M.O.2    Cunningham, D.3
  • 13
    • 0025043987 scopus 로고
    • 19F nuclear magnetic resonance spectroscopy pharmacokinetics
    • 19F nuclear magnetic resonance spectroscopy pharmacokinetics. J Clin Oncol 1990, 8, 1868-1873.
    • (1990) J Clin Oncol , vol.8 , pp. 1868-1873
    • Presant, C.A.1    Wolf, W.2    Albright, M.J.3
  • 14
    • 0028231298 scopus 로고
    • Association of intratumoral pharmacokinetics of 5-fluorouracil with clinical response
    • Presant CA, Wolf W, Waluch C, et al. Association of intratumoral pharmacokinetics of 5-fluorouracil with clinical response. The Lancet 1994, 343, 1184-1185.
    • (1994) The Lancet , vol.343 , pp. 1184-1185
    • Presant, C.A.1    Wolf, W.2    Waluch, C.3
  • 15
    • 0002685062 scopus 로고
    • Fluorinated Pyrimidines
    • In Chabner BA, Collins JM, eds. Philadelphia, JB Lippincott Company
    • Grem JL. Fluorinated Pyrimidines. In Chabner BA, Collins JM, eds. Cancer Chemotherapy: Principles & Practice. Philadelphia, JB Lippincott Company, 1990, 180-224.
    • (1990) Cancer Chemotherapy: Principles & Practice , pp. 180-224
    • Grem, J.L.1
  • 19
    • 0020619318 scopus 로고
    • STRIPE: An interactive computer programme for the analysis of drug pharmacokinetics
    • Johnson A, Woolard RC. STRIPE: an interactive computer programme for the analysis of drug pharmacokinetics. J Pharmacol Methods. 9:1982;193-199.
    • (1982) J Pharmacol Methods , vol.9 , pp. 193-199
    • Johnson, A.1    Woolard, R.C.2
  • 20
    • 0027966042 scopus 로고
    • Metabolic consequences of a reversed pH gradient in rat tumours
    • Stubbs M, Rodrigues LM, Howe FA, et al. Metabolic consequences of a reversed pH gradient in rat tumours. Cancer Res 1994, 54, 4011-4016.
    • (1994) Cancer Res , vol.54 , pp. 4011-4016
    • Stubbs, M.1    Rodrigues, L.M.2    Howe, F.A.3
  • 21
    • 0028358687 scopus 로고
    • In vivo monitoring of fluoropyrimidine metabolites: Magnetic resonance spectroscopy in the evaluation of 5-fluorouracil
    • Findlay MPN, Leach MO. In vivo monitoring of fluoropyrimidine metabolites: magnetic resonance spectroscopy in the evaluation of 5-fluorouracil. Anticancer Res. 5:1994;260-280.
    • (1994) Anticancer Res , vol.5 , pp. 260-280
    • Findlay, M.P.N.1    Leach, M.O.2
  • 22
    • 0024757133 scopus 로고
    • 19F-MRS studies of fluoropyrimidine chemotherapy. A review
    • 19F-MRS studies of fluoropyrimidine chemotherapy. A review. NMR Biomed. 2:1989;133-141.
    • (1989) NMR Biomed , vol.2 , pp. 133-141
    • McSheehy, P.M.J.1    Griffiths, J.R.2
  • 23
    • 0028577327 scopus 로고
    • Dihydropyrimidine dehydrogenase and clinical pharmacology of 5-fluorouracil (review)
    • Milano G, Etienne M-C. Dihydropyrimidine dehydrogenase and clinical pharmacology of 5-fluorouracil (review). Anticancer Res. 14:1994;2295-2298.
    • (1994) Anticancer Res , vol.14 , pp. 2295-2298
    • Milano, G.1    Etienne M-C2
  • 26
    • 0025214307 scopus 로고
    • Effect of 5-fluorouracil combination therapy on RNA processing in human colon carcinoma cells
    • Greenhalgh DA, Parish JH. Effect of 5-fluorouracil combination therapy on RNA processing in human colon carcinoma cells. Br J Cancer. 61:1990;415-419.
    • (1990) Br J Cancer , vol.61 , pp. 415-419
    • Greenhalgh, D.A.1    Parish, J.H.2
  • 27
    • 0024414582 scopus 로고
    • Interferon effects upon fluorouracil metabolism by HL-60 cells
    • Elias I, Sandoval JM. Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem Biophys Res Commun. 163:1989;867-874.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 867-874
    • Elias, I.1    Sandoval, J.M.2
  • 28
    • 0026600296 scopus 로고
    • Stimulation of 5-fluorouracil metabolic activation by interferon-α In human colon carcinoma cells
    • Schwartz EL, Hoffman M, O'Connor CJ, Wadler S. Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cells. Biochem Biophys Res Commun. 182:1992;1232-1239.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1232-1239
    • Schwartz, E.L.1    Hoffman, M.2    O'Connor, C.J.3    Wadler, S.4
  • 29
    • 0025043811 scopus 로고
    • Interaction of interferon-γ And 5-fluorouracil in the H630 human colon carcinoma cell line
    • Chu E, Zinn S, Boarman D, Allegra CJ. Interaction of interferon-γ and 5-fluorouracil in the H630 human colon carcinoma cell line. Cancer Res. 50:1990;5834-5840.
    • (1990) Cancer Res , vol.50 , pp. 5834-5840
    • Chu, E.1    Zinn, S.2    Boarman, D.3    Allegra, C.J.4
  • 31
    • 0028987635 scopus 로고
    • Potentiation of 5-fluorouracil-Leucovorin activity by α2a-interferon in colon adenocarcinoma xenografts
    • Houghton JA, Cheshire PJ, Morton CL, Stewart CF. Potentiation of 5-fluorouracil-Leucovorin activity by α2a-interferon in colon adenocarcinoma xenografts. Clin Cancer Res. 1:1995;33-40.
    • (1995) Clin Cancer Res , vol.1 , pp. 33-40
    • Houghton, J.A.1    Cheshire, P.J.2    Morton, C.L.3    Stewart, C.F.4
  • 32
    • 0026490284 scopus 로고
    • Decreased catabolism of 5-fluorouracil in peripheral blood mononuclear cells during combination therapy with fluorouracil, leucovorin, and interferon-α-2a
    • Yee LK, Allegra CJ, Steinberg SM, Grem JL. Decreased catabolism of 5-fluorouracil in peripheral blood mononuclear cells during combination therapy with fluorouracil, leucovorin, and interferon-α-2a. J Natl Cancer Inst. 84:1992;1820-1825.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1820-1825
    • Yee, L.K.1    Allegra, C.J.2    Steinberg, S.M.3    Grem, J.L.4
  • 34
    • 0027246491 scopus 로고
    • Mechanisms by which interferon potentiates chemotherapy
    • Hoffman MA, Wadler S. Mechanisms by which interferon potentiates chemotherapy. Clinical Sci Rev. 11:1993;310-313.
    • (1993) Clinical Sci Rev , vol.11 , pp. 310-313
    • Hoffman, M.A.1    Wadler, S.2
  • 35
    • 0028040592 scopus 로고
    • Lack of effect of interferon-α2a upon 5-fluorouracil pharmacokinetics
    • Seymour MT, Patel N, Johnston A, Joel SP, Slevin ML. Lack of effect of interferon-α2a upon 5-fluorouracil pharmacokinetics. Br J Cancer. 70:1994;724-728.
    • (1994) Br J Cancer , vol.70 , pp. 724-728
    • Seymour, M.T.1    Patel, N.2    Johnston, A.3    Joel, S.P.4    Slevin, M.L.5
  • 36
    • 0025771650 scopus 로고
    • Are cancer cells acidic?
    • Griffiths JR. Are cancer cells acidic? Br J Cancer. 64:1991;425-427.
    • (1991) Br J Cancer , vol.64 , pp. 425-427
    • Griffiths, J.R.1
  • 38
    • 85044684018 scopus 로고    scopus 로고
    • Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells
    • in press.
    • Ojugo ASE, McSheehy PMJ, Stubbs M, et al. Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells. Br J Cancer, in press.
    • Br J Cancer
    • Ojugo, A.S.E.1    McSheehy, P.M.J.2    Stubbs, M.3
  • 39
    • 0025880431 scopus 로고
    • Primary amines enhance the antiviral activity of interferon against a membrane virus: Role of intracellular pH
    • Maheshwari RK, Sidhu GS, Bhartiya D, Friedman RM. Primary amines enhance the antiviral activity of interferon against a membrane virus: role of intracellular pH. J Gen Virol. 72:1991;2143-2152.
    • (1991) J Gen Virol , vol.72 , pp. 2143-2152
    • Maheshwari, R.K.1    Sidhu, G.S.2    Bhartiya, D.3    Friedman, R.M.4
  • 40
    • 0023706752 scopus 로고
    • An increase in intracellular pH is a general response of promonocytic cells to differentiating agents
    • Ladoux A, Damais C, Krawice I, Abita J-P, Frelin C. An increase in intracellular pH is a general response of promonocytic cells to differentiating agents. FEBS Lett. 234:1988;353-356.
    • (1988) FEBS Lett , vol.234 , pp. 353-356
    • Ladoux, A.1    Damais, C.2    Krawice, I.3    Abita J-P4    Frelin, C.5
  • 42
    • 0022558709 scopus 로고
    • 31P-Nuclear magnetic resonance analysis of interferon-induced alterations of phospholipid metabolites in interferon-sensitive and interferon-resistant Friend leukaemia cell tumours in mice
    • 31P-Nuclear magnetic resonance analysis of interferon-induced alterations of phospholipid metabolites in interferon-sensitive and interferon-resistant Friend leukaemia cell tumours in mice. Cancer Res. 46:1986;2849-2857.
    • (1986) Cancer Res , vol.46 , pp. 2849-2857
    • Proietti, E.1    Carpinelli, G.2    Divito, M.3    Belardelli, F.4    Gressor, I.5    Podo, F.6
  • 44
    • 0027534409 scopus 로고
    • Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumours as compared with plasma
    • Peters GJ, Lankelma J, Kok RM, et al. Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumours as compared with plasma. Cancer Chemother Pharmacol 1993, 31, 269-276.
    • (1993) Cancer Chemother Pharmacol , vol.31 , pp. 269-276
    • Peters, G.J.1    Lankelma, J.2    Kok, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.