Subgrouping immunomodulating β-glucans by monitoring IFN-γ and NO syntheses

Drug Development Research

Volumn 42, Issue 1, 1997, Pages 35-40

  Hashimoto, Tomoe ^a   Ohno, Naohito ^a   Yadomae, Toshiro ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

glucan; IFN ; Nitric oxide

Indexed keywords

BETA GLUCAN; BIOLOGICAL RESPONSE MODIFIER; GAMMA INTERFERON; NITRIC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; IMMUNOMODULATION; MACROPHAGE; MOUSE; NONHUMAN;

EID: 0031423510     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199709)42:1<35::AID-DDR3>3.0.CO;2-S     Document Type: Article

References (18)

1. Fujimoto S, Orita K, Kondoh T, Taguchi T, Yoshida K, Kimura T, Ogawa N, Furue H (1988): Schizophyllan. Biotherapy 2:500-508.
2. Hashimoto, T, Ohno N, Adachi Y, Yadomae T (1997): Nitric oxide synthesis in murine peritoneal macrophages by fungal β-glucans. Biol Pharm Bull 20:1006-1009.
3. Howard AY, Kenneth JH (1995): Role of interferon-γ in immune cell regulation. J Leukoc Biol 58:373-381.
4. Itoh K, Suzuki R, Umezu Y, Hanaumi K, Kumagai K (1982): Studies of marine large granular lymphocytes. II. Tissue, strain, and age distributions of LGL and LAL. J Immunol 291:2658-2662.
5. Miura NN, Ohno N, Adachi Y, Aketagawa J, Tamura H, Tanaka S, Yadomae T (1995): Comparison of the blood clearance of triple-and single-helical Schizophyllan in mice. Biol Pharm Bull 18: 1242-1247.
6. Nagi N, Ohno N, Adachi Y, Aketagawa J, Tamura H, Shibata Y, Tanaka S, Yadomae T (1993): Application of limulus test (G pathway) for the detection of different conformers of (1→3)-β-glucan. Biol Pharm Bull 16:822-828.
7. Ohno X, Adachi Y, Suzuki I, Sato K, Oikawa S, Yadomae T (1986a): Characterization of the antitumor glucan obtained from the liquid cultured Grifolafrondosa. Chem Pharm Bull 34:1709-1715.
8. Ohno N, Suzuki I, Yadomae T (1986a): Structure and antitumor activity of a beta-1,β-glucan isolated from the cultured filtrate of Sclerotinia sclerotiorum IFO 9395. Chem Pharm Bull 34:1362-1365.
9. Ohno N, Miura T, Salto K, Nishijima M, Nfiyazaki T, Yadomae T (1992): Physiochemical characteristics and antitumor activities of a highly branched fungal (1→3)-β-glucan, OL-2, isolated from Omphalia lapidescens. Biol Pharm Bull 40:2215-2218.
10. Ohno N, Saito K, Nemoto J, Kaneko S, Adachi Y, Nishijima M, Miyazaki T, Yadomae T (1993): Immunopharmacological characterization of a highly branched fungal (1→3)-β-glucan, OL-2, isolated from Omphalia lapidescens. Biol Pharm Bull 16:414-419.
11. Ohno N, Egawa Y, Hashimoto T, Adachi Y, Yadomae T (1996a): Effect of β-glucans on nitric oxide synthesis by peritoneal macrophages in mice. Biol Pharm Bull 19:608-612.
12. Ohno N, Hashimoto T, Adachi Y, Yadomae T (1996b): Conformation dependency of nitric oxide synthesis of murine peritoneal macrophages by β-glucans in vitro. Immunol Lett 52:1-7 (corrigendum, 53:157-163).
13. Ross GD, Vetvicka V (1993): CR3 (CD11b, CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Clin Exp Immunol 92:181-184.
14. Taguchi T, Kaneko Y, Chihara G (1988): Lentinan. Biotherapy 2:509-521.
15. Tsuchiya Y, Igarashi M, Inoue M, Kumagai K (1989): Cytokine-related immunomodulating activities of an anti-tumor glucan, Sizofiran (SPG). J Pharmacobiol-Dyn 12:616-625.
16. Tsuchiya Y, Matsunami M, Inoue M, Sato S, Asano T, Yajima M (1991): Effect of a glucan, sizofiran, on natural-killer activity of 5-fluorouracil-treated murine bone marrow cells. Cancer Immunol Immunother 34:17-23.
17. Tsuchiya Y, Yang ZB, Nakahashi S, Arika T (1993): Acceleration of natural killer (NK) cell recovery by a glucan, sizofiran, in anti-asialo GM1 antibody treated mice. Int J Immunopharmacol 15:783-792.
18. +Tcells: A new family of T cells. Immunol Today 17:71-76.