A light microscopic radioautographic study on protein synthesis in pulmonary cells of aging mice

Acta Histochemica et Cytochemica

Volumn 30, Issue 5-6, 1997, Pages 463-470

  Sun, Lin ^a   Gao, Fulu ^a   Nagata, Tetsuji ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aging; Lung; Mice; Protein synthesis; Radioautography

Indexed keywords

EID: 0031419845     PISSN: 00445991     EISSN: None     Source Type: Journal    
DOI: 10.1267/ahc.30.463     Document Type: Article

References (44)

1. Adenuga, G. A., Mazaev, A. G. and Olowookere, J. O.: The peculiarities of protein and RNA syntheses in the hepatic mitochondria of young and old animals: Studies without the use of an antibiotic. Exp. Gerontol. 23; 35-41, 1988.
2. Askin, F. B. and Kuhn, C.: The cellular origin of pulmonary surfactant. Lab. Invest. 25; 260-268, 1971.
3. Berk, J. L., Franzblau, C. and Goldstein R. H.: Recombinant interleukin-1β inhibits elastin formation by a neonatal rat lung fibroblast subtype. J. Biol. Chem. 266; 3192-3197, 1991.
4. Burri, P. H.: The postnatal growth of the rat lung. III. Morphology. Anat. Rec. 180; 77-98, 1974.
5. Bustany, P., Trenque, T., Crambes, O. and Moulin, M.: Restoration of brain protein synthesis in mature and aged rats by a DA agonist, piribedil. Fundam. Clin. Pharmacol. 9; 458-468, 1995.
6. Campagnone, R., Regan, J., Rich, C. B., Miller, M., Keene, D. R., Sakai, L. and Foster, J. A.: Methods in laboratory investigation, pulmonary fibroblasts: A model system for studying elastin synthesis. Lab. Invest. 56; 224-230, 1987.
7. D, Costa, A. P., Xu, X., Ingram, R. L. and Sonntag, W. E.: Insulin-like growth factor-1 stimulation of protein synthesis is attenuated in cerebral cortex of aging rats. Neuroscience 65; 805-813, 1995.
8. Gao, F.: Study on the macromolecular synthesis in aging mouse seminiferous tubules by light and electron microscopic radioautography. Cell. Mol. Biol. 39; 659-672, 1993.
9. Gao, F., Ma, H., Sun, L., Jin, C. and Nagata, T.: Electron microscopic radioautographic study on the nucleic acids and protein syntheses in the aging mouse testis. Med. Electron Microsc. 27; 360-362, 1994.
10. Gao, F., Sun, L., Chen, S., Jin, C., Ma, H. and Nagata, T.: Radioautographic study on the macromolecular synthesis of Leydig cells in the testis of aging mouse. In "Radioautography in Medicine", ed. by T. Nagata, Shinshu University Press, Matsumoto, 1994, pp. 220-224.
11. Gao, F., Chen, S., Sun, L., Kang, W., Wang, Z. and Nagata, T.: Radioautographic study on the macromolecular synthesis of Leydig cells in aging mice testis. Cell. Mol. Biol. 41; 145-150, 1995.
12. Goldspink, D. F.: Pre-and post-natal growth and protein turnover in the lung of the rat. Biochem. J. 242; 275-279, 1987.
13. Goldspink, D. F. and Kelly, F. J.: Protein turnover and growth in the whole body, liver and kidney of the rat from the foetus to senility. Biochem. J. 217; 507-516, 1984.
14. Goldspink, D. F. and Merry, B. J.: Changes in protein turnover and growth of the rat lung in response to ageing and long-term dietary restriction. Mech. Ageing Dev. 42; 253-262, 1988.
15. Goldspink, D. F., Lewis, S. E. M. and Kelly, F. J.: Protein synthesis during the developmental growth of the small and large intestine of the rat. Biochem. J. 217; 527-534, 1984.
16. Gozes, I., Cronin, B. L. and Moskowitz, M. A.: Protein synthesis in rat brain microvessels decreases with aging. J. Neurochem. 36; 1311-1315, 1981.
17. Kimball, S. R., Vary, T. C. and Jefferson, L. S.: Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues. Biochem. J. 286; 263-268, 1992.
18. Layman, D. K., Ricca, G. A. and Richardson, A.: The effect of age on protein synthesis and ribosome aggregation to messenger RNA in rat liver. Arch. Biochem. Biophys. 173; 246-254, 1976.
19. Lewis, S. E. M., Kelly, F. J. and Goldspink, D. F.: Pre-and post-natal growth and protein turnover in smooth muscle, heart and slow-and fast-twitch skeletal muscles of the rat. Biochem. J. 217; 517-526, 1984.
20. Ma, H., Gao, F. and Nagata, T.: Study on protein synthesis in the livers of aging mice by means of electron microscopic radioautography. J. Clin. Electron Microsc. 25; 5-6, 1992.
21. Ma, H., Gao, F., Olea, M. T. and Nagata, T.: Protein synthesis in the livers of aging mice studied by electron microscopic radioautography. Cell. Mol. Biol. 37; 607-615, 1991.
22. Ma, H., Chen, S., Gao, F. and Nagata, T.: DNA, RNA and protein synthesis in the livers of aging mice studied by electron microscopic radioautography. In "Radioautography in Medicine", ed. by T. Nagata, Shinshu University Press, Matsumoto, 1994, pp. 122-126.
23. Ma, H., Gao, F., Sun, L., Jin, C. and Nagata, T.: Electron microscopic radioautographic study on the syntheses of DNA, RNA, and protein in the livers of aging mice. Med. Electron Microsc. 27; 352-354, 1994.
24. Marshak, T. L., Dungenova, R. E. and Brodskii, V. Y.: Protein synthesis in the liver and cerebellum of rats growing at different rates of intensity. Ontogenez 26; 430-436, 1995.
25. Mays, P. K., McAnulty, R. J. and Laurent, G. J.: Age-related changes in lung collagen metabolism. Am. Rev. Respir. Dis. 140; 410-416, 1989.
26. Mays, P. K., McAnulty, R. J. and Laurent, G. J.: Age-related changes in rates of protein synthesis and degradation in rat tissues. Mech. Ageing Dev. 59; 229-241, 1991.
27. McGowan, S. E., Harvey, C. S. and Jackson, S. K.: Retinoids, retinoic acid receptors, and cytoplasmic retinoid binding proteins in perinatal rat lung fibroblasts. Am. J. Physiol. (Lung Cell. Mol. Physiol. 13) 269; L463-L472, 1995.
28. Nagata, T.: Simple method for mass production of radioautographs. Saibo (The Cell) 14; 40-50, 1982.
29. Nagata, T.: Radiolabeling of soluble and insoluble compounds as demonstrated by light and electron microscopy. In "Recent Advances in Cellular and Molecular Biology", vol. 6, ed. by R. J. Wegmann and M. A. Wegmann, Peeters Press, Leuven, 1992, pp. 9-21.
30. Nagata, T.: Quantitative analysis of histochemical reactions: Image analysis of light and electron microscopic radioautogram. Acta Histochem. Cytochem. 26; 281-291, 1993.
31. Nagata, T.: Quantitative light and electron microscopic radioautographic studies on macromolecular synthesis in several organs of prenatal and postnatal aging mice. Chin. J. Histochem. Cytochem. 2; 106-108, 1993.
32. Nagata, T.: Application of electron microscopic radioautography to clinical electron microscopy. Med. Electron. Microsc. 27; 191-212, 1994.
33. Nagata, T.: Light and electron microscopic radioautographic studies on macromolecular synthesis in digestive organs of aging mice. Cell. Mol. Biol. 41; 21-38, 1995.
34. Nagata, T. and Usuda, N.: Electron microscopic radioautography of protein synthesis in pancreatic cells of aging mice. Acta Histochem. Cytochem. 26; 481-481, 1993.
35. Rattan, S. I. S.: Synthesis, modifications, and turnover of proteins during aging. Exp. Gerontol. 31; 33-47, 1996.
36. Riis, B., Rattan, S. I. S., Derventzi, A. and Clark, B. F. C.: Reduced levels of ADP-ribosylatable elongation factor-2 in aged and SV40-transformed human cell cultures. FEBS Lett. 266; 45-47, 1990.
37. Shahbazian, F. M., Jacobs, M. and Lajtha, A.: Rates of protein synthesis in brain and other organs. Int. J. Dev. Neurosci. 5; 39-42, 1987.
38. Sun, L.: Age-related changes of RNA synthesis in the lungs of aging mice by light and electron microscopic radioautography. Cell. Mol. Biol. 41; 1061-1072, 1995.
39. Sun, L., Gao, F. and Nagata, T.: Study on the DNA synthesis of pulmonary cells in aging mice by light microscopic radioautography. Cell. Mol. Biol. 41; 851-859, 1995.
40. Sun, L., Gao, F., Duan, H. and Nagata, T.: Light microscopic radioautography of DNA synthesis in pulmonary cells in aging mouse. In "Radioautography in Medicine", ed. by T. Nagata, Shinshu University Press, Matsumoto, 1994, pp. 201-205.
41. Sun, L., Gao, F., Jin, C., Duan, H. and Nagata, T.: An electron microscopic radioautographic study on the DNA synthesis of pulmonary tissue cells in aging mice. Med. Electron Microsc. 28; 130-132, 1995.
42. Toriyama, K.: Study on the aging changes of DNA and protein synthesis of bipolar and photoreceptor cells of mouse retina by light and electron microscopic radioautography. Cell. Mol. Biol. 41; 593-601, 1995.
43. 3H] lysine. Neurosci. Lett. 18; 225-230, 1980.
44. Yamada, A. T.: Timely and topologically defined protein synthesis in the peri-implanting mouse endometrium revealed by light and electron microscopic radioautography. Cell. Mol. Biol. 39; 1-12, 1993.