The prognostic value of MDR1 gene expression in primary untreated neuroblastoma

European Journal of Cancer

Volumn 33, Issue 12, 1997, Pages 2031-2036

  Haber, M ^a,b   Bordow, S B ^a   Haber, P S ^c   Marshall, G M ^a,b   Stewart, B W ^a,b   Norris, M D ^a,b  

^a SYDNEY CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c PRINCE OF WALES HOSPITAL   (Australia)

Author keywords

MDR1; Multidrug resistance; Multidrug resistance associated protein (MRP); MYCN oncogene; Neuroblastoma; Polymerase chain reaction (PCR)

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; COMPLEMENTARY DNA; EPIPODOPHYLLOTOXIN; RNA; VINCA ALKALOID;

CANCER CHEMOTHERAPY; CHILDHOOD CANCER; CONFERENCE PAPER; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; NEUROBLASTOMA; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS;

EID: 0031418281     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(97)00229-3     Document Type: Conference Paper

References (26)

1. Brodeur GM, Castleberry RP. Neuroblastoma. In Pizzo PA, Poplack DG, eds. Principles and Practice of Pediatric Oncology, 2nd edn. Philadelphia, PA, JB Lippincott Co, 1993, 739-767.
2. Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985, 313, 1111-1116.
3. Brodeur GM, Azar C, Brother M, et al. Neuroblastoma: effect of genetic factors on prognosis and treatment. Cancer 1992, 70, 1685-1694.
4. Roninson IB, ed. Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells. New York, Plenum, 1991.
5. Cole SPC, Bhardwaj G, Gerlach JH, et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 1992, 258, 1650-1654.
6. Grant C. E., Valdimarsson G., Hipfner D. R., et al. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res. 54:1994;357-361.
7. Zaman GJR, Flens MJ, van Leusden MR, et al. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc Natl Acad Sci USA 1994, 9, 8822-8826.
8. Norris M. D., Bordow S. B., Marshall G. M., et al. Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma. N Engl J Med. 334:1996;231-238.
9. Chan HSL, Haddad G, Thorner PS, et al. P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N Engl J Med 1991 325, 1608-1614.
10. Bourhis J., Benard J., Hartmann O., et al. Correlation of MDR1 gene expression with chemotherapy in neuroblastoma. J Natl Cancer Inst. 81:1989;1401-1405.
11. Goldstein LJ, Fojo AT, Ueda K, et al. Expression of the multidrug resistance, MDR1, gene in neuroblastoma. J Clin Oncol 1990, 8, 128-136.
12. Corrias MV, Cornaglia-Ferraris P, Di Martino D, et al. Expression of multiple drug resistance gene, MDR1, and N-myc oncogene in an Italian population of human neuroblastoma patients. Anticancer Res 1990, 10, 897-902.
13. Favrot M, Combaret V, Goillot E, et al. Expression of P-glycoprotein restricted to normal cells in neuroblastoma biopsies. Br J Cancer 1991, 64, 233-238.
14. Nakagawara A, Kadomatsu K, Sato S, et al. Inverse correlation between expression of multidrug resistance gene and N-myc oncogene in human neuroblastomas. Cancer Res 1990, 50, 3043-3047.
15. Telford D. J., Kavallaris M., White L., et al. Association of N-myc amplification with neuroblastoma: The Australian and New Zealand experience. J Paediatr Child Health. 28:1992;58-63.
16. Bordow S. B., Haber M., Madafiglio J., et al. Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma. Cancer Res. 54:1994;5036-5040.
17. Del Poeta G, Stasi R, Aronica G, et al. Clinical relevance of P-glycoprotein expression in de novo acute myeloid leukemia. Blood 1996, 87, 1997-2004.
18. Campos L, Guyotat D, Archimbaud E, et al. Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis. Blood 1992, 79, 473-476.
19. Goasguen JE, Dossot J-M, Fardel O, et al. Expression of the multidrug resistance-associated P-glycoprotein (P170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood 1993, 81, 2394-2398.
20. Chan H. S. L., Thorner P. S., Haddad G., Ling V. Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcomas of childhood. J Clin Oncol. 8:1990;689-704.
21. Baldini N, Scotlandi K, Barbanti-Brodano G, et al. Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome. N Engl J Med 1995, 333, 1380-1385.
22. Bates SE, Mickley LA, Chen Y-N, et al. Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation. Mol Cell Biol 1989, 9, 4337-4344.
23. Ferrandis E., Babajko S., Benard J. MYCN protein activates the MDR1 gene proximal promoter in human neuroblasts. Proc Am Assoc Cancer Res. 36:1995;338.
24. Norris MD, Bordow SB, Haber PS, et al. Evidence that the N-myc oncogene regulates MRP gene expression in neuroblastoma. Eur J Cancer 1997, 33(12), 1911-1916.
25. Ferrandis E., Benard J. Activation of the human MDR1 gene promoter in differentiated neuroblasts. Int J Cancer. 54:1993;987-991.
26. Ferrandis E., Da Silva J., Riou G., Benard J. Coactivation of the MDR1 and MYCN genes in human neuroblastoma cells during the metastatic process in the nude mouse. Cancer Res. 54:1994;2256-2261.