In vitro culture of B-lymphocytes derived from Epstein-Barr-virus- associated posttransplant lymphoproliferative disease: Cytokine production and effect of interferon-alpha

In Vitro Cellular and Developmental Biology - Animal

Volumn 33, Issue 10, 1997, Pages 803-808

  Randhawa, Parmjeet ^a,d   Whiteside, Theresa ^c   Zeevi, Adriana ^a   Nalesnik, Michael ^a   Alvares, Carmelita ^b   Gollin, Susanne M ^b   Demetris, Jake ^a   Locker, Joseph ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

Author keywords

Cell culture model; Epstein Barr virus; Lymphoproliferative; Posttransplant

Indexed keywords

ALPHA INTERFERON; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2; LYMPHOTOXIN;

ADULT; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CASE REPORT; CHILD; EPSTEIN BARR VIRUS; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; LYMPHOPROLIFERATIVE DISEASE; MALE; ORGAN TRANSPLANTATION; VIRUS REPLICATION;

HUMAN HERPESVIRUS 4;

EID: 0031417122     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-997-0160-9     Document Type: Article

References (49)

1. Alvares, C. J.; McKnight, J. L. C.; Herberman, R. B., et al. Cytogenetic findings in post-transplant lymphoproliferative disorder. Cytogenet. Cell Genet. 69:124A; 1995.
2. Avila-Carino, J.; Torsteinsdottir, S.; Ehlm-Henriksson, B., et al. Search for the critical characteristics of phenotypically different B cell lines, Burkitt lymphoma cells and lymphoblastoid cell lines, which determine differences in their functional interaction with allogeneic lymphocytes. Cancer Immunol. Immunother. 34:128-132; 1991.
3. Benjamin, D.; Knobloch, T. J.; Dayton, M. A. Human B-cell interleukin-10: B cell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secrete large quantitles of Interleukin-10. Blood 80:1289-1298; 1992.
4. Burdin, N.; Peronne, C.; Banchereau, J., et al. Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J. Exp. Med. 177:295-304; 1993.
5. Cen, H.; Wiliams, P. A.; McWilliams, H. P., et al. Evidence for restricted Epstein-Barr virus latent gene expression and anti-EBNA antibody response in solid organ transplant recipients with post-transplant lymphoproliferative disease. Blood 81:1393-1403; 1993
6. 2. Proc. Natl. Acad. Sci. USA 85:8037-8041; 1988.
7. Clarke, P. A.; Sharp, N. A.; Arrand, J. R., et al. Epstein-Barr virus gene expression in interferon-treated cells. Implications for the regulation of protein synthesis and the antiviral state. Biochim. Biophys. Acta 1050:167-173; 1990.
8. Cleary, M. L.; Nalesnik, M. A.; Shearer, W. T., et al. Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus. Blood 72:349-352; 1988.
9. Cohen, J. H. M.; Revillard, J. P.; Magaud, J. P., et al. B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation. J. Natl. Cancer Inst. 78:235-242; 1987.
10. Defrance, T.; Vanbervliet, B.; Briere, F., et al. Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J. Exp. Med. 175:671-682; 1992.
11. de Waal Malefyt, R.; Abrams, J.; Bennett, B., et al. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes. J. Exp. Med. 174:1209-1220; 1991a.
12. de Waal Malefyt, R.; Haanen, J.; Spits, H., et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915-924; 1991b.
13. Estrov Z.; Kurzrock, R.; Pocsik, E., et al. Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected cell lines. J. Exp. Med. 177:763-774; 1993.
14. Favrot, M. C.; Maritaz, O.; Suzuki, T., et al. EBV-negative and positive Burkitt cell lines variably express receptors for B-cell activation and differentiation. Int. J. Cancer 38:901-906; 1986.
15. Granger, G. A.; Moore, G. E.; White, J. G., et al. Production of lymphotoxin and migration inhibitory factor by established human lymphocytic cell lines. J. Immunol. 104:1476-1485; 1970
16. Hanto, D. W.; Sakamoto, K.; Purtilo, D. T., et al. The Epstein-Barr virus in the pathogenesis of posttransplant lymphoproliferative disorders. Surgery 90:204-213; 1981.
17. Heslop, H. E.; Bianchi, A. C. M.; Cordingley, F. T., et al. Effects of interferon α on autocrine growth factor loops in B lymphoproliferative disorders. J. Exp. Med. 172:1729-1734; 1990.
18. Mitelman, F. ISCN Guidelines for cancer cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. Basel: S. Karger; 1991.
19. Jarvis, J. E.; Ball, G.; Rickinson, A. B., et al. Cytogenetic studies on human lymphoblastoid cell lines from Burkitt's lymphoma, and other sources. Int. J. Cancer 14:716-721; 1974.
20. Jonak, G. J.; Friedland, B. K.; Anton, E. D., et al. Regulation of c-myc RNA and its proteins in daudi cells by interferon-β. J. Interferon Res. 7:41-52; 1987.
21. Kolman, J. L.; Kolman, C. J.; Miller, G. Marked variation in the size of genomic plasmids among members of a family of related Epstein-Barr viruses. Proc. Natl. Acad. Sci. USA 89:7772-7776; 1992.
22. Liberati, A. M.; Sohippa, M.; Portuesi, M. G., et al. IFN-β induced biochemical and immunological modifications in hairy cell leukemia patients. Haematologica 76:375-382: 1990.
23. Locker, J.; Nalesnik, M. Molecular genetic analysis of lymphoid tumors arising after organ transplantation. Am. J. Pathol. 135:977-987; 1989.
24. Maeyer, E. D.; Maeyer-Guignard, J. D. Interferons. In: Thomson, A., ed. The cytokine handbook. San Diego: Academic Press; 1991:215-240.
25. Mangeney, M.; Richard, Y.; Coulaud, D., et al. CD77: an antigen of germinal center B cells entering apoptosis. Eur. J. Immunol. 21:1131-1140; 1991.
26. Mathur, A.; Kamat, D. M.; Filipovich, A. H., et al. Immunoregulatory abnormalities in patients with Epstein-Barr virus-associated B cell lymphoproliferalive disorders. Transplantation 57:1042-1045; 1994.
27. Nalesnik, M. A.; Jaffe, R.; Starzl, T. E., et al. The pathology of posttransplant lymphoproliferative disorders occurring in the setting of cyclosporine A-prednisone immunosuppression. Am. J. Pathol. 133:173-192; 1988.
28. Nilsson, K.; Klein, G. Phenotypic and cytogenetic characteristics of human B-lymphoid cell lines and their relevance for the etiology of Burkitt's lymphoma. Adv. Cancer Res. 37:319-380; 1982.
29. Penn, I. Immunosuppression - a contributory factor in lymphoma formation. Clin. Transplant. 6:214-219; 1992.
30. Picarella, D. E.; Kratz, A.; Li, C. B., et al. Insulitis in transgenic mice expressing tumor necrosis factor beta in the pancreas. Proc. Natl. Acad. Sci. USA 89:10036-10040; 1992.
31. Pizarro, T. T; Malinowska, K.; Kovacs, E. J., et al. Induction of TNF-alpha and TNF-beta gene expression in rat cardiac transplants during allograft rejection. Transplantation 56:399-404; 1993.
32. Randhawa, P. S.; Demetris, A. J.; Nalesnik, M. A. The potential role of cytokines in the pathogenesis of Epstein-Barr virus associated posttransplant lymphoproliferative disease. Leukemia Lymphoma 15:383-387; 1994a.
33. Randhawa, P. S.; Zeevi, A.; Alvares, C., et al. Morphologic and immunophenotypic characterization of a cell line derived from liver tissue with Epstein-Barr virus associated post-transplant lymphoproliferative disease. In Vitro Cell. Dev. Biol. 30A:400-406; 1994b.
34. Randhawa, P. S.; Nalesnik, M.; Demetris, A. J., et al. Interleukin-10 production by a B cell line derived from human post-transplant lymphoproliferative disease. Hematologic. Oncol. 13:13-18; 1995.
35. Rooney, C. M.; Gregory, C. D.; Rowe, M., et al. Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines. J. Natl. Cancer Inst. 77:681-687; 1986.
36. Rousset, F.; Burdin, N.; Vezzio, N., et al. Interleukin-10 and human B lymphocytes. In: Tursz, T.; Pagano, J. S.; Ablashi, D. V., et al., ed. The Epstein Barr virus and associated diseases. Paris: Colloque INSERM/John Libbey Eurotext Ltd.; 1993:309-315.
37. Rousset, F.; Garcia, E.; Defrance, T., et al. Inlerleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89:1890-1893; 1992.
38. Saito, R.; Prehn, J.; Zuo, X. J., et al. The participation of tumor necrosis factor in the pathogenesis of lung allograft rejection in the rat. Transplantation 55:967-972; 1993.
39. Sato, H.; Takimoto, T.; Tanaka, J., et al. Concatameric replication of the Epstein-Barr virus: structure of the termini in virus-producer and newly transformed cell lines. J. Virol. 64:5295-5300; 1990.
40. Seregina, T. M.; Mekshenkov, M. I.; Turetskaya, R. L., et al. An autocrine growth factor constitutively produced by a human lymphoblastoid B-cell line is serologically related to lymphotoxin (TNF-β). Mol. Immunol. 26:339-342; 1989.
41. Shapiro, R. S.; Chauvenet, A.; McGuire, W., et al. Treatment of B-cell lymphoproliferative disorders with interferon alpha and intravenous gamma globulin. N. Engl. J. Med. 322:1334; 1988.
42. Sharp, N. A.; Arrand, J. R.; Clemens, M. J. Epstein-Barr virus replication in interferon-treated cells. J. Gen. Virol. 70:2521-2526; 1989.
43. Starzl, T. E.; Nalesnik. M. A.; Porter, K. A., et al. Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet 1:583-587; 1984.
44. Steel, C. M.; Shade, M.; Woodward, M. A. Chromosome aberrations acquired in-vitro by human B-cell lines. I. Gains and losses of material. J. Natl. Cancer Inst. 65:95-99; 1980.
45. Steel, C. M.; Woodward, M. A.; Davidson, C., et al. Non-random chromosome gains in human lymphoblastoid cell lines. Nature 270:349-351; 1977.
46. Sung, S. S. J.; Jung, L. K. L.; Walters, J. A., et al. Production of lymphotoxin by isolated human tonsillar B lymphocytes and B lymphocyte cell lines. J. Clin. Invest. 84:236-243; 1989.
47. Thomas, J. A.; Hotchin, N. A.; Allday, M. J., et al. Immunohistology of Epstein-Barr virus associated antigens in B cell disorders from immu-nocompromised individuals. Transplantation 49:944-953; 1989.
48. Wu, T. T.; Swerdlow, S. S.; Locker, J., et al. Pathological analysis of recurrent post-transplant lymphoproliferative disorders. Transplant. Proc. 27:1193-1199; 1995.
49. Zech, L.; Hoagland, U.; Nilsson, K., et al. Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas. Int. J. Cancer 17:47-56; 1976.