-
1
-
-
84912671626
-
Cardiovascular profile of UD-CG 115, a new orally and long acting cardiotonic compound, not related to β-mimetics or cardiac glycosides
-
Diederen W, Dammgen J, Kadatz R. Cardiovascular profile of UD-CG 115, a new orally and long acting cardiotonic compound, not related to β-mimetics or cardiac glycosides. Naunyn Schmiedebergs Arch Pharmacol 1982;321:141-6.
-
(1982)
Naunyn Schmiedebergs Arch Pharmacol
, vol.321
, pp. 141-146
-
-
Diederen, W.1
Dammgen, J.2
Kadatz, R.3
-
2
-
-
0024428451
-
Hemodynamic profile of the cardiotonic agent pimobendan
-
van Meel JC, Diederen W. Hemodynamic profile of the cardiotonic agent pimobendan. J Cardiovasc Pharmacol 1989;14(suppl II):S1-6.
-
(1989)
J Cardiovasc Pharmacol
, vol.14
, Issue.2 SUPPL.
-
-
Van Meel, J.C.1
Diederen, W.2
-
4
-
-
0023944395
-
Pimobendan (UD-CG 115 BS) in the treatment of severe congestive heart failure: An acute haemodynamic crossover and double-blind study with two different doses
-
Walter M, Liebens I, Goethals H, Renard M, Dresse A, Bernard R. Pimobendan (UD-CG 115 BS) in the treatment of severe congestive heart failure: an acute haemodynamic crossover and double-blind study with two different doses. Br J Clin Pharmacol 1988; 25:323-9.
-
(1988)
Br J Clin Pharmacol
, vol.25
, pp. 323-329
-
-
Walter, M.1
Liebens, I.2
Goethals, H.3
Renard, M.4
Dresse, A.5
Bernard, R.6
-
5
-
-
0024466152
-
Clinical efficacy of pimobendan (UD-CG 115 BS) in patients with chronic congestive heart failure
-
Baumann G, Ningel K, Permanetter B. Clinical efficacy of pimobendan (UD-CG 115 BS) in patients with chronic congestive heart failure. J Cardiovasc Pharmacol 1989;14(suppl II):S23-30.
-
(1989)
J Cardiovasc Pharmacol
, vol.14
, Issue.2 SUPPL.
-
-
Baumann, G.1
Ningel, K.2
Permanetter, B.3
-
6
-
-
0021345075
-
UD-CG 115-A cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle
-
Honerjager P, Heiss A, Schafer-Korting M, Schonsteiner G, Reiter M. UD-CG 115-A cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle. Naunyn Schmiedebergs Arch Pharmacol 1984;325:259-69.
-
(1984)
Naunyn Schmiedebergs Arch Pharmacol
, vol.325
, pp. 259-269
-
-
Honerjager, P.1
Heiss, A.2
Schafer-Korting, M.3
Schonsteiner, G.4
Reiter, M.5
-
7
-
-
0022648976
-
Phosphodiesterase inhibiting properties of newer inotropic agents
-
Scholz H, Meyer W. Phosphodiesterase inhibiting properties of newer inotropic agents. Circulation 1986;73(suppl III):99-108.
-
(1986)
Circulation
, vol.73
, Issue.3 SUPPL.
, pp. 99-108
-
-
Scholz, H.1
Meyer, W.2
-
8
-
-
0021687326
-
Effect on contractility of skinned fibres from mammalian heart and smooth muscle by a new benzimidazole derivative 4,5-dihydro-6-[2-(methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)- phyidazolinone
-
Ruegg J, Pfitzer G, Eubler D, Zeugner C. Effect on contractility of skinned fibres from mammalian heart and smooth muscle by a new benzimidazole derivative 4,5-dihydro-6-[2-(methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)- phyidazolinone. Arzneimittelforschung 1984;34:1736-8.
-
(1984)
Arzneimittelforschung
, vol.34
, pp. 1736-1738
-
-
Ruegg, J.1
Pfitzer, G.2
Eubler, D.3
Zeugner, C.4
-
9
-
-
0028072772
-
Effects of pimobendan, its active metabolite UD-CG 212 Cl, and milrinone on isolated blood vessels
-
Fujimoto S. Effects of pimobendan, its active metabolite UD-CG 212 Cl, and milrinone on isolated blood vessels. Eur J Pharmacol 1994;265:159-66.
-
(1994)
Eur J Pharmacol
, vol.265
, pp. 159-166
-
-
Fujimoto, S.1
-
10
-
-
0026515374
-
Electrophysiological actions of the pimobendan metabolite, UG-CD 212 Cl, in guinea pig myocardium
-
Westfall MV, Wahler GM, Fujino K, Solaro RJ. Electrophysiological actions of the pimobendan metabolite, UG-CD 212 Cl, in guinea pig myocardium. J Pharmacol Exp Ther 1991;260:58-63.
-
(1991)
J Pharmacol Exp Ther
, vol.260
, pp. 58-63
-
-
Westfall, M.V.1
Wahler, G.M.2
Fujino, K.3
Solaro, R.J.4
-
11
-
-
0028965128
-
+ channel of vascular smooth muscle cells
-
+ channel of vascular smooth muscle cells. Life Sci 1995;56:291-8.
-
(1995)
Life Sci
, vol.56
, pp. 291-298
-
-
Miyoshi, H.1
Nakaya, Y.2
-
12
-
-
0024208155
-
Pharmacokinetic profile of OPC-8212 in humans: A new, nonglycosidic, inotropic agent
-
Ohnishi A, Ishizaki T. Pharmacokinetic profile of OPC-8212 in humans: a new, nonglycosidic, inotropic agent. J Clin Pharmacol 1988;28:719-26.
-
(1988)
J Clin Pharmacol
, vol.28
, pp. 719-726
-
-
Ohnishi, A.1
Ishizaki, T.2
-
13
-
-
0025298548
-
Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
-
Cell Physiol 28
-
Nelson MT, Patlak JB, Worley JF, Atanded NB. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am J Physiol 1990;259(Cell Physiol 28):C3-18.
-
(1990)
Am J Physiol
, vol.259
-
-
Nelson, M.T.1
Patlak, J.B.2
Worley, J.F.3
Atanded, N.B.4
-
14
-
-
0025914660
-
Calcium-activated potassium channels from coronary smooth muscle reconstituted in lipid bilayers
-
Heart Circ Physiol
-
Toro L, Vaca L, Stefani E. Calcium-activated potassium channels from coronary smooth muscle reconstituted in lipid bilayers. Am J Physiol 1991;260 (Heart Circ Physiol):H1779-89.
-
(1991)
Am J Physiol
, vol.260
-
-
Toro, L.1
Vaca, L.2
Stefani, E.3
-
15
-
-
0023677647
-
Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas
-
Heart Circ Physiol
-
Sadoshima J, Akaike N, Kanaide H, Nakamura M. Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas. Am J Physiol 1988;255 (Heart Circ Physiol):H754-9.
-
(1988)
Am J Physiol
, vol.255
-
-
Sadoshima, J.1
Akaike, N.2
Kanaide, H.3
Nakamura, M.4
-
17
-
-
0015097243
-
The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers
-
Ross R. The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. J Cell Biol 1971;50:172-86.
-
(1971)
J Cell Biol
, vol.50
, pp. 172-186
-
-
Ross, R.1
-
18
-
-
0025254352
-
Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats
-
Fujimoto S, Matsuda T. Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats. J Pharmacol Exp Ther 1990;252:1304-11.
-
(1990)
J Pharmacol Exp Ther
, vol.252
, pp. 1304-1311
-
-
Fujimoto, S.1
Matsuda, T.2
-
19
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FG. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 1981;391: 85-100.
-
(1981)
Pflugers Arch
, vol.391
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
Sakmann, B.4
Sigworth, F.G.5
-
21
-
-
0025248571
-
Inhibition of forskolin-induced neunte outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells
-
Chijiwa T, Mishima A, Hagiwara M, et al. Inhibition of forskolin-induced neunte outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 1990;265:5267-72.
-
(1990)
J Biol Chem
, vol.265
, pp. 5267-5272
-
-
Chijiwa, T.1
Mishima, A.2
Hagiwara, M.3
-
22
-
-
0028076281
-
Use of the cyclic AMP antagonist, Rp-cAMPS, to distinguish between cyclic AMP-dependent and cyclic AMP-independent contractile responses in rat ventricular cardiomyocytes
-
Bell D, McDermott BJ. Use of the cyclic AMP antagonist, Rp-cAMPS, to distinguish between cyclic AMP-dependent and cyclic AMP-independent contractile responses in rat ventricular cardiomyocytes. J Mol Cell Cardiol 1994;26:1439-48.
-
(1994)
J Mol Cell Cardiol
, vol.26
, pp. 1439-1448
-
-
Bell, D.1
McDermott, B.J.2
-
23
-
-
0022628578
-
New positive inotropic agents in the treatment of congestive heart failure: Mechanisms of action and recent clinical developments
-
Colucci WS, Wright RF, Braunwald E. New positive inotropic agents in the treatment of congestive heart failure: mechanisms of action and recent clinical developments. N Engl J Med 1986;314:349-58.
-
(1986)
N Engl J Med
, vol.314
, pp. 349-358
-
-
Colucci, W.S.1
Wright, R.F.2
Braunwald, E.3
-
24
-
-
0025978355
-
Different mechanisms involved in the positive inotropic effects of benzimidazole derivative UD-CG 115 BS (pimobendan) and its demethylated metabolite UD-CG 212 Cl in canine ventricular myocardium
-
Endoh M, Shibasaki T, Satoh H, Norota I, Ishihata A. Different mechanisms involved in the positive inotropic effects of benzimidazole derivative UD-CG 115 BS (pimobendan) and its demethylated metabolite UD-CG 212 Cl in canine ventricular myocardium. J Cardiovasc Pharmacol 1991;17:365-75.
-
(1991)
J Cardiovasc Pharmacol
, vol.17
, pp. 365-375
-
-
Endoh, M.1
Shibasaki, T.2
Satoh, H.3
Norota, I.4
Ishihata, A.5
-
25
-
-
0025982134
-
Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium
-
Bohm M, Morano I, Pieske B, et al. Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium. Circ Res 1991;68:689-701.
-
(1991)
Circ Res
, vol.68
, pp. 689-701
-
-
Bohm, M.1
Morano, I.2
Pieske, B.3
-
26
-
-
0023797004
-
The positive inotropic effect of pimobendan involves stereospecific increases in the calcium sensitivity of cardiac myofilaments
-
Fujino K, Sperelakis N, Solaro RJ. The positive inotropic effect of pimobendan involves stereospecific increases in the calcium sensitivity of cardiac myofilaments. Circ Res 1988;63:911-22.
-
(1988)
Circ Res
, vol.63
, pp. 911-922
-
-
Fujino, K.1
Sperelakis, N.2
Solaro, R.J.3
-
27
-
-
0022540094
-
Cardiovascular profile of pimobendan, a benzimidazole-pyridazinone derivative with vasodilating and inotropic properties
-
Verdouw PD, Hartog JM, Duncker DJ, Roth W, Saxena PR. Cardiovascular profile of pimobendan, a benzimidazole-pyridazinone derivative with vasodilating and inotropic properties. Eur J Pharmacol 1986;126:21-30.
-
(1986)
Eur J Pharmacol
, vol.126
, pp. 21-30
-
-
Verdouw, P.D.1
Hartog, J.M.2
Duncker, D.J.3
Roth, W.4
Saxena, P.R.5
-
28
-
-
0027483273
-
Calcium sensitization with pimobendan: Pharmacology, haemodynamic improvement, and sudden death in patients with chronic congestive heart failure
-
Hagemeijer F. Calcium sensitization with pimobendan: pharmacology, haemodynamic improvement, and sudden death in patients with chronic congestive heart failure. Eur Heart J 1993;14:551-66.
-
(1993)
Eur Heart J
, vol.14
, pp. 551-566
-
-
Hagemeijer, F.1
-
30
-
-
0029108913
-
Physiological roles and properties of potassium channels in arterial smooth muscle
-
Cell Physiol 37
-
Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 1995;268(Cell Physiol 37):C799-822.
-
(1995)
Am J Physiol
, vol.268
-
-
Nelson, M.T.1
Quayle, J.M.2
-
31
-
-
0024817158
-
Outward potassium current in freshly isolated smooth muscle cell of dog coronary arteries
-
Wilde DW, Lee KS. Outward potassium current in freshly isolated smooth muscle cell of dog coronary arteries. Circ Res 1989; 65: 1718-34.
-
(1989)
Circ Res
, vol.65
, pp. 1718-1734
-
-
Wilde, D.W.1
Lee, K.S.2
|