Synthetic strategies to lower affinity for CYP2D6

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 22, Issue 4, 1997, Pages 291-294

  Halliday, Rachel C ^a   Jones, B C ^a   Park, B K ^b   Smith, D A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Affinity; CYP2D6; In vitro; Inhibition

Indexed keywords

BUFURALOL; CYTOCHROME P450; IMIPRAMINE;

CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROXYLATION;

EID: 0031413836     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190959     Document Type: Conference Paper

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