Spontaneous and cholecystokinin-octapeptide-promoted regeneration of the pancreas following L-arginine-induced pancreatitis in rat

International Journal of Pancreatology

Volumn 22, Issue 3, 1997, Pages 193-200

  Hegyi, Péter ^a   Takács, Tamás ^a   Jármay, Katalin ^a   Nagy, István ^a   Czakó, László ^a   Lonovics, János ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Arginine; Cholecystokinin octapeptide; Experimental pancreatitis; Regeneration

Indexed keywords

AMYLASE; ARGININE; CHOLECYSTOKININ OCTAPEPTIDE; DNA; ENTEROPEPTIDASE; GLUCOSE; GLYCINE; SODIUM CHLORIDE; TRYPSIN; TRYPSINOGEN;

AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; CONTROLLED STUDY; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORGAN WEIGHT; PANCREAS ISLET; PANCREAS NECROSIS; PANCREATITIS; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE REGENERATION; TISSUE REPAIR;

AMYLASES; ANIMALS; ARGININE; BLOOD GLUCOSE; BODY WEIGHT; DNA; MALE; ORGAN SIZE; PANCREAS; PANCREATITIS; PROTEINS; RATS; RATS, WISTAR; REGENERATION; SINCALIDE; TRYPSIN;

EID: 0031410134     PISSN: 01694197     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Mizunuma T, Kawamura S, Kishino Y. Effects of injecting excess arginine on rat pancreas. J Nutr 1984; 114: 467-471.
2. Kishino Y, Kawamura S. Pancreatic damage induced by injecting a large dose of arginine. Wirchows Archiv (Cell Pathol) 1984; 47: 149-155.
3. Tani S, Itoh H, Okabayashi Y, Nakamura T, Fujii M, Fujisawa T, Koide M, Otsuki M. New model of acute necrotizing pancreatitis induced by excessive doses of arginine in rats. Dig Dis Sci 1990; 35: 367-374.
4. Delaney CP, McGeeney KF, Dervan P, Fitzpatrick JM. Pancreatic atrophy: A new model using serial intraperitoneal injections of L-arginine. Scand J Gastroenterol 1993; 28: 1086-1090.
5. Takács T, Nagy I, Pap À, Varró V. Effect of a new CCK receptor antagonist on pancreatic secretion and groth. Digestion 1987; 38: 60.
6. Solomon TE. Regulation of exocrine pancreatic cell proliferation and enzyme synthesis, in Physiology of Gastrointestinal Tract, Johnson LR, ed. Raven, New York, 1989; pp. 873-892.
7. Pap À, Boros L, Hajnal F. Essential role of cholecystokinin in pancreatic regeneration after 60% distal resection in rats. Pancreas 1991; 6: 412-418.
8. Takács T, Nagy I, Pap À, Varró V. The effect of long-term administration of lorglumide (CR 1409) on rat pancreatic growth and enzyme composition. Pancreas 1990; 5: 606-610.
9. Lászik GZ, Berger Z, Pap À, Tóth KG, Varró V. Course and regression of acute interstitial pancreatitis induced in rats by repeated serial subcutaneous cholecystokinin-okta-peptide injections. Int J Pancreatol 1989; 5: 347-358.
10. Tani S, Itoh H, Koide M, Okabayasi Y, Otsuki M. Involvement of endogenus cholecystokinin in the development of acute pancreatitis induced by closed duodenal loop. Pancreas 1993; 8: 109-115.
11. Jurkowska G, Grondin G, Morisset J. Involvement of endogenous cholecystokinin in pancreatic regeneration after cerulein-induced acute pancreatitis. Pancreas 1992; 7: 295-304.
12. Ceska M, Birath K, Brown B. A new and rapid method for the clinical determination of a-amylase activates in human serum and urine. Clin Chim Acta 1969; 26: 437-444.
13. Hyvärinen A, Nikkilä EA. Specific determination of blood glucose with o-toluidine. Clin Chim Acta 1962; 7: 140-144.
14. Schneider WC. Determination of nucleic acids in tissues by pentose analysis. Meth Enzymol 1957; 3: 680-684.
15. Giles KW, Myers A. An improved diphenylamine method for the estimation of deoxyribonucleic acid. Nature (UK) 1965; 206: 93.
16. Nagy I, Pap À, Varró V. Time-course of changes in pancreatic size and enzyme composition in rats during starvation. Int J Pancreatol 1989; 5: 35-45.
17. Solomon TE, Petersen H, Elashoff J, Grossman MT. Interaction of caerulein and secretin on pancreatic size and composition in rat. Am J Physol 1978; 235: E714-E719.
18. Dagorn JC. Nonparallel enzyme secretion from the rat pancreas: in vivo studies. J Physiol (UK) 1978; 280: 435-448.
19. Erlanger BF, Kokowsky W, Cohen W. The preparation and properties of two new chromogenic substrates of trypsin. Arch Biochem Biophys 1961; 95: 271-278.
20. Gou J. Micro biuret method for protein determination; determination of total protein in cerebrospinal fluid. Scand J Clin Lab Invest 1953; 5: 218-222.
21. Odaira C, Berger Z, Iovanna JL, Sarles H. Localized necrohemorrhagic pancreatitis in the rat after pancreatic interstitial trypsin Injection. Digestion 1986; 34: 68-77.
22. Waever C, Bishop AE, Polak JM. Pancreatic changes elicited by chronic administration of excess L-arginine. Exp Mol Pathol 1994; 60: 71-87.
23. Scheele G. Regulation of gene expression in the exocrine pancreas, in The Exocrine Pancreas, Go VL, Gardner JD, Brooks FP, Lebenthal E, Di Magno EP, Scheele GA, eds. Raven, New York, 1986; pp. 55-69.
24. Yanatory Y, Fujita T. Hypertrophy and hyperplasia in the endocrine and exocrine pancreas of rats fed soyben trypsin inhibitor or repeatedly injected with pancreozymin. Arch Histol Jpn 1976; 39: 67-78.