Experimental disc herniation: Evaluation of the natural course

Spine

Volumn 22, Issue 24, 1997, Pages 2894-2899

  Otani, Koji ^a   Arai, Itaru ^a   Mao, Guang Ping ^a   Konno, Shinichi ^a   Olmarker, Kjell ^a,b   Kikuchi, Shinichi ^a,c  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c Fukushima Medical University   (Japan)

Author keywords

Disc herniation; Magnetic resonance imaging; Nerve function; Nerve roots; Nucleus pulposus; Sciatica

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOG; INTERVERTEBRAL DISK HERNIA; NERVE CONDUCTION; NERVE ROOT INJURY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS PULPOSUS; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANIMALS; DISEASE MODELS, ANIMAL; DOGS; ELECTRIC STIMULATION; INJECTIONS, SPINAL; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DISPLACEMENT; MAGNETIC RESONANCE IMAGING; NERVE COMPRESSION SYNDROMES; NEURAL CONDUCTION; SODIUM CHLORIDE; SPINAL NERVE ROOTS;

EID: 0031410015     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199712150-00012     Document Type: Article

References (15)

1. Bush K, Cowan N, Katz DE, Gishen P. The natural history of sciatica associated with disc pathology. A prospective study. Spine 1992;17:1205-12.
2. Cornefjord M, Olmarker K, Rydevik B, Nordborg C. Mechanical and biochemical injury of spinal nerve roots. A morphological and neurophysiological study. Eur Spine J 1996;5: 187-92.
3. Gibson MJ, Buckley J, Mawhinney R, Mulholland RC, Worthington BS. Magnetic resonance imaging and discography in the diagnosis of disc degeneration. J Bone Joint Surg Br 1986;68:369-73.
4. Kayama S, Konno S, Olmarker K, Kikuchi S. Incision of the anulus fibrosus induces nerve root morphologic, vascular and functional changes. Spine 1996;21:2539-43.
5. Modic MT, Ross JS, Obuchowski NA, Browning KH, Cianflocco AJ, Mazanes DJ. Contrast-enhanced MR imaging in acute lumbar radiculopathy: a pilot study of the natural history. Radiology 1995;195:429-35.
6. Nachemson AL. Newest knowledge of back pain. A critical look. Clin Orthop 1992;279:8-20.
7. Olmarker K, Rydevik B, Nordborg C. Autologous nucleus pulposus induces neurophysiologic and histologic changes in porcine cauda equina nerve roots. Spine 1993;18:1425-32.
8. Olmarker K, Byrd ÜG, Cornefjord M, Nordborg C, Rydevik B. Effects of methyl-prednisolone on nucleus pulposus-induced nerve root injury. Spine 1994;19:1803-8.
9. Olmarker K, Blomquist J, Stromberg J, Nannmark U, Thomsen P, Rydevik B. Inflammatogenic properties of nucleus pulposus. Spine 1995;20:665-9.
10. Olmarker K, Rydevik B, Nordborg C. Ultrastructural changes in spinal nerve roots induced by autologous nucleus pulposus. Spine 1996;21:411-4.
11. Olmarker K. Experimental basis of sciatica. J Orthop Sci 1996;1:230-42.
12. Olmarker K, Yabuki S, Nordborg C, Rydevik B. The effects of normal, frozen and hyaluronidase digested nucleus pulposus on nerve root function. Spine (In press).
13. Osti OL, Vernon-Roberts B, Fraser RD. Anulus tears and intervertebral disc degeneration. An experimental study using an animal model. Spine 1990;15:762-7.
14. Otani K, Arai I, Mao GP, Konno S, Olmarker K, Kikuchi S. Nucleus pulposus-induced nerve root injury. The relationship between blood flow and nerve conduction velocity (submitted manuscript).
15. Weber H. The natural history of disc herniation and the influence of intervention. Spine 1194;19:2234-8.