Interaction between a semisynthetic diet and indole-3-carbinol on mammary tumor incidence in Balb/cfC3H mice

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4333-4337

  Malloy, Virginia L ^a   Bradlow, H Leon ^a,b   Orentreich, Norman ^a  

^a Orentreich Foundation for the Advancement of Science Inc   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Indole 3 carbinol; Mouse mammary tumors; Semisynthetic diet

Indexed keywords

3 INDOLEMETHANOL; FATTY ACID; INDOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST TUMOR; CANCER PREVENTION; CONTROLLED STUDY; DIET; FAT INTAKE; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMAL FEED; ANIMALS; ANTICARCINOGENIC AGENTS; DIETARY FATS, UNSATURATED; ENDOMETRIAL NEOPLASMS; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; FEMALE; GENES, RAS; INCIDENCE; INDOLES; MAMMARY NEOPLASMS, EXPERIMENTAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, TRANSGENIC; TIME FACTORS; TRANSFECTION;

EID: 0031409790     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Bradlow HL, Michnovicz JJ, Telang NT and Osborne MP: Effect of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 12: 1571-1574, 1991.
2. Tiwari RK, Bradlow HL, Telang NT, and Osborne MP: Selective responses of human breast cancer cells to indole-3-carbinol, a chemopreventive agent. J Natl Cancer Inst 86: 121-126, 1994.
3. Grubbs CJ, Steele VE, Casebolt T, Juliana MM, Eto I, Whitaker LM, Dragnev KH, Kelloff GJ, and Lubet RL: Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. Anticancer Res 15: 709-716, 1995.
4. Kojima T, Tanaka T, and Mori M: Chemoprevention of spontaneous endometrial cancer in female Donryku rats by dietary indole-3-carbinol. Cancer Res 54: 1446-1449, 1994.
5. Kabat GC, Chang CJ, Sparano JA, Sepkovic DW, Hu XP, Khalil A, Rosenblatt R, and Bradlow HL:Urinary estrogen metabolites and breast cancer: A case-control study. Cancer Epidemiol and Biomarkers Prev 6: 500-504, 1997
6. Sepkovic DW, Bradlow HL, Ho G, Hankinsin SE, Gong L, Osborne M and Fishman J: Estrogen metabolite ratios and risk assessment of hormone-related cancers. Assay validation and prediction of cervical cancer risk. Ann NY Acad Sci 765: 312-316, 1995.
7. Michnovicz JJ, and Bradlow HL: Induction of estradiol metabolism by dietary indole-3-carbinol in humans. J Natl Cancer Inst 82: 947-949, 1991.
8. Bradlow HL, Michnovicz JJ, Halper M, Miller DG, Wong GYC, and Osborne MP: Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiol Biomarkers Prev 3: 591-595 1994.
9. Michnovicz JJ, Adlercreutz H and Bradlow HL: Changes in urinary estrogens following indole-3-carbinol in humans. J Natl Cancer Inst 89: 719-723, 1997.
10. Taioli E, Garte SJ, Trachman J, Garbers S, Sepkovic DW, and Osborne MP: CyP450/A1 genotype, estradiol, metabolism and breast cancer. Cancer Prevent (in press),1996.
11. Bradlow, HL., Sepkovic, DW., and Auborn, K: Correlation of the therapeutic response in laryngeal papillomas and induction of 2-hydroxylation by indole-3-carbinol. Workshop of Recurrent Respiratory Papillomatosis: Head and Neck Diseases Associated with Papillomaviruses. Quebec, Canada, 1995.
12. Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz, JJ and Bradlow HL: Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochem Pharmacol 45: 1139-1151, 1993.
13. Niwa T, Swaneck G, and Bradlow HL: Alterations in estradiol metabolism in MCF-7 cells induced by treatment with indole-3-carbinol and related compounds. Steroids 59: 523-527, 1994.
14. Nandi S and McGrath CM: Mammary neoplasia in mice. Adv Cancer Res 17: 354-414, 1973.
15. Sinn E, Muller W, Pattengall P, Teplar I, Wallace R, and Leder, P: Coexpression on MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo. Cell 49: 465-475, 1987.
16. Dupont Technical Bulletin. January 1989.
17. Schneider J, Kinne D, Fracchia A, Pierce V, Anderson KE, Bradlow HL, and Fishman J: Abnormal oxidative metabolism of estradiol in women with breast cancer. Proc Natl Acad Sci USA 79: 3047-3051, 1982.
18. Fishman J, Schneider J, Hershcopf RJ, and Bradlow HL: Increased estrogen 16α-hydroxylase activity in women with breast endrometrial cancer. J Steroid Biochem 20: 1077-1081, 1984.
19. Osborne MP, Karmali RA, and Bradlow HL: Omega-3-fatty acids: Modulation of estrogen metabolism and potential for breast cancer prevention. Cancer Invest 6: 629-631, 1988.
20. Abraham S, Faulkin LJ, Hillyard LA, and Mitchell DJ: Effect of dietary fat on tumorigenesis in the mouse mammary gland. J Natl Cancer Inst 72: 1421-1429, 1984.
21. Carrol KK, and Khor HT: Effects of level and type of dietary fat on incidence of mammary tumors induced in female Sprague Dawley rats by 7,12 dimethylbenz(a)anthracene. Lipids 6: 415-420, 1971.
22. Rao GA and Abraham S: Enhanced growth rate of transplanted mammary adenocarcinoma induced in C3H mice by dietary linoleate. J Natl Cancer Inst 56: 431-432, 1976.
23. Thigpen JE, Lung-An L, Richter CB, Lebetkin EH, and Jameson CW: The mouse bioassay for the detection of estrogenic activity of purified, certified and standard open and closed formula rodent diets. Lab Anim Sci 37: 602-605, 1987.
24. Thigpen JE, Lebetkin, EH Dawes ML, Richter CB and Crawford D: The mouse bioassay for the detection of estrogenic activity in rodent diets: III. Stimulation of uterine weight by dextrose, sucrose and corn starch. Lab Ani Sci 37: 606-609, 1987.