-
1
-
-
0028115911
-
Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173
-
Smetsers T. Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173 Leukemia 8 1994 129 140
-
(1994)
Leukemia
, vol.8
, pp. 129-140
-
-
Smetsers, T.1
-
2
-
-
0028945287
-
Phosphorothioate BCR-ABL antisense oligonucleotides induce cell death, but fail to reduce cellular Bcr-abl protein levels
-
Smetsers T. Phosphorothioate BCR-ABL antisense oligonucleotides induce cell death, but fail to reduce cellular Bcr-abl protein levels Leukemia 9 1995 118 130
-
(1995)
Leukemia
, vol.9
, pp. 118-130
-
-
Smetsers, T.1
-
3
-
-
0027170689
-
Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide
-
Skorski T. Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide J. Clin. Invest. 92 1993 194 202
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 194-202
-
-
Skorski, T.1
-
4
-
-
0025883201
-
Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides
-
Szczylik C. Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides Science 253 1991 562 565
-
(1991)
Science
, vol.253
, pp. 562-565
-
-
Szczylik, C.1
-
5
-
-
0027070730
-
In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides
-
Ratajczak M. In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides Proc. Natl. Acad. Sci. U. S.A. 80 1992 11823 11827
-
(1992)
, pp. 11823-11827
-
-
Ratajczak, M.1
-
6
-
-
0029029421
-
c-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis
-
Skorski T. c-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis Cancer Res. 55 1995 2275 2278
-
(1995)
Cancer Res.
, vol.55
, pp. 2275-2278
-
-
Skorski, T.1
-
7
-
-
0026089494
-
Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging
-
Calabretta B. Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging Proc. Natl. Acad. Sci. U. S.A. 88 1991 2351 2355
-
(1991)
, pp. 2351-2355
-
-
Calabretta, B.1
-
8
-
-
0023227831
-
A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1
-
Heikkila R. A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 Nature 328 1987 445 449
-
(1987)
Nature
, vol.328
, pp. 445-449
-
-
Heikkila, R.1
-
9
-
-
0026754351
-
Acute-and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligonudeotides
-
Ratajczak M. Acute-and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligonudeotides Blood 79 1992 1956 1961
-
(1992)
Blood
, vol.79
, pp. 1956-1961
-
-
Ratajczak, M.1
-
10
-
-
0028263606
-
Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth
-
bcr/abl : implication for RAS-dependent Philadelphia chromosome positive cell growth J. Exp. Med. 179 1994 1855 1865
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1855-1865
-
-
Skorski, T.1
-
11
-
-
0026651984
-
Inhibition of leukemia cell proliferation by receptormediated uptake of c-myb antisense oligodeoxynucleotides
-
Citro G. Inhibition of leukemia cell proliferation by receptormediated uptake of c-myb antisense oligodeoxynucleotides Proc. Natl. Acad. Sci. U. S. A. 89 1992 7031 7035
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 7031-7035
-
-
Citro, G.1
-
12
-
-
0028586823
-
Antisense BCR-ABL oligomers cause nonspecific inhibition of chronic myeloid leukemia cell lines
-
O'Brien S. Antisense BCR-ABL oligomers cause nonspecific inhibition of chronic myeloid leukemia cell lines Leukemia 8 1994 2156 2162
-
(1994)
Leukemia
, vol.8
, pp. 2156-2162
-
-
O'Brien, S.1
-
13
-
-
0027729703
-
Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial
-
Bayever E. Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial Antisense Res. Dev. 3 1993 383 390
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 383-390
-
-
Bayever, E.1
-
14
-
-
0026586858
-
Safety aspects of gene therapy
-
Cornetta K. Safety aspects of gene therapy Br. J. Haematol. 80 1992 421 426
-
(1992)
Br. J. Haematol.
, vol.80
, pp. 421-426
-
-
Cornetta, K.1
-
15
-
-
0026310571
-
Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides
-
Ho P.T. Ishiguro K. Wickstrom E. Sartorelli A.C. Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides Antisense Res. Dev. 1 1991 329 342
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 329-342
-
-
Ho, P.T.1
Ishiguro, K.2
Wickstrom, E.3
Sartorelli, A.C.4
-
16
-
-
0027203638
-
BCR-ABL antisense purging in chronic myeloid leukaemia
-
Kirkland M. BCR-ABL antisense purging in chronic myeloid leukaemia Lancet 342 1993 614
-
(1993)
Lancet
, vol.342
, pp. 614
-
-
Kirkland, M.1
-
17
-
-
0028236818
-
Liposomal delivery of methylphosphonate antisense oligonucleotides in chronic myelogenous leukemia
-
Tari A. Tucker S. Deisseroth A. Lopez-Berestein G. Liposomal delivery of methylphosphonate antisense oligonucleotides in chronic myelogenous leukemia Blood 84 1994 601 607
-
(1994)
Blood
, vol.84
, pp. 601-607
-
-
Tari, A.1
Tucker, S.2
Deisseroth, A.3
Lopez-Berestein, G.4
-
18
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans
-
Nabel G. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans Proc. Natl. Acad. Sci. U. S. A. 90 1993 11307 11311
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 11307-11311
-
-
Nabel, G.1
-
19
-
-
0024291288
-
Simple RNA enzymes with new and highly specific endoribonuclease activity
-
Haseloff J. Gerlach W. Simple RNA enzymes with new and highly specific endoribonuclease activity Nature 334 1988 585 591
-
(1988)
Nature
, vol.334
, pp. 585-591
-
-
Haseloff, J.1
Gerlach, W.2
-
20
-
-
0027489372
-
In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA
-
Lange W. Cantin E. Finke J. Dolken G. In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA Leukemia 7 1993 1786 1794
-
(1993)
Leukemia
, vol.7
, pp. 1786-1794
-
-
Lange, W.1
Cantin, E.2
Finke, J.3
Dolken, G.4
-
21
-
-
0027819241
-
Ribozyme-mediated cleavage of the bcr/abl transcript expressed in chronic myeloid leukemia
-
Wright Z. Ribozyme-mediated cleavage of the bcr/abl transcript expressed in chronic myeloid leukemia Exp. Hematol. 21 1993 1714 1719
-
(1993)
Exp. Hematol.
, vol.21
, pp. 1714-1719
-
-
Wright, Z.1
-
22
-
-
0027218359
-
Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line
-
Snyder D. Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line Blood 82 1993 600 605
-
(1993)
Blood
, vol.82
, pp. 600-605
-
-
Snyder, D.1
-
23
-
-
0028939524
-
Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias
-
Leopold L. Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias Blood 85 1995 2162 2170
-
(1995)
Blood
, vol.85
, pp. 2162-2170
-
-
Leopold, L.1
-
24
-
-
0028047536
-
Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs
-
Lange W Dashalakis M. Finke J. Dolken G. Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs FEBS Lett. 338 1994 175 178
-
(1994)
FEBS Lett.
, vol.338
, pp. 175-178
-
-
Lange, W1
Dashalakis, M.2
Finke, J.3
Dolken, G.4
-
25
-
-
0028219456
-
DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein
-
Inaba T. DNA-binding specificity and trans -activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein Mol. Cell. Biol. 14 1994 34003 34013
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 34003-34013
-
-
Inaba, T.1
-
26
-
-
0025642663
-
Regulation of gene expression with double-stranded phosphorothioate oligonudeotides
-
Bielinska A. Shivdasani R.A. Zhang L. Nabel G.J. Regulation of gene expression with double-stranded phosphorothioate oligonudeotides Science 250 1990 997 1000
-
(1990)
Science
, vol.250
, pp. 997-1000
-
-
Bielinska, A.1
Shivdasani, R.A.2
Zhang, L.3
Nabel, G.J.4
-
27
-
-
0026469803
-
The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts
-
Chu B.C.F. Orgel L.E. The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts Nucleic Acids Res. 20 1992 5857 5858
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5857-5858
-
-
Chu, B.C.F.1
Orgel, L.E.2
-
28
-
-
0025744428
-
Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels
-
Postel E.H. Flint S.J. Kessler D.J. Hogan M.E. Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels Proc. Natl. Acad. Sci. U. S. A. 88 1991 8227 8231
-
(1991)
, pp. 8227-8231
-
-
Postel, E.H.1
Flint, S.J.2
Kessler, D.J.3
Hogan, M.E.4
-
29
-
-
0027506794
-
Retrovirally transduced antisense sequences stably suppress p210bcr-abl expression and inhibit the proliferation of BCR/ABL-containing cell lines
-
bcr-abl expression and inhibit the proliferation of BCR/ABL-containing cell lines Blood 81 1993 502 509
-
(1993)
Blood
, vol.81
, pp. 502-509
-
-
Martiat, P.1
-
30
-
-
85119460542
-
Retroviral vectors expressing antisense to the BCR promoter region inhibit human CML cell lines but not primary CD34+ HLA-DR+ cells
-
+ cells Exp. Hematol. 23 1995 906
-
(1995)
Exp. Hematol.
, vol.23
, pp. 906
-
-
Chen, K.1
-
31
-
-
0027392819
-
Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow
-
Leemhuis T. Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow Blood 81 1993 801 807
-
(1993)
Blood
, vol.81
, pp. 801-807
-
-
Leemhuis, T.1
-
32
-
-
0026592510
-
Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression
-
Verfaillie C.M. Miller W.J. Boylan K. McGlave P.B. Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression Blood 79 1992 1003 1010
-
(1992)
Blood
, vol.79
, pp. 1003-1010
-
-
Verfaillie, C.M.1
Miller, W.J.2
Boylan, K.3
McGlave, P.B.4
-
33
-
-
85119468272
-
The 30/35 kD chymotryptic fragment of fibronectin enhances retroviral-mediated gene transfer (RMGT) in chronic myelogenous leukemia (CML) CD34+ HLA-DR+ and CD34+ HLA-DR− bone marrow progenitors
-
− bone marrow progenitors Exp. Hematol. 23 1995 934
-
(1995)
Exp. Hematol.
, vol.23
, pp. 934
-
-
Traycoff, C.M.1
-
34
-
-
0028457625
-
A retroviral vector expressing human interferon γ upregulates MHC antigen expression in human breast cancer and leukemia cell lines
-
Cornetta K. A retroviral vector expressing human interferon γ upregulates MHC antigen expression in human breast cancer and leukemia cell lines Cancer Gene Ther. 1 1994 91 98
-
(1994)
Cancer Gene Ther.
, vol.1
, pp. 91-98
-
-
Cornetta, K.1
-
35
-
-
0025604195
-
Retroviral vector-mediated γ-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity
-
Gansbacher B. Retroviral vector-mediated γ-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity Cancer Res. 50 1990 7820 7825
-
(1990)
Cancer Res.
, vol.50
, pp. 7820-7825
-
-
Gansbacher, B.1
-
36
-
-
0028334810
-
Retroviral mediated gene transfer in chronic myelogenous leukemia
-
Cornetta K. Retroviral mediated gene transfer in chronic myelogenous leukemia Br. J. Haematol. 87 1994 308 316
-
(1994)
Br. J. Haematol.
, vol.87
, pp. 308-316
-
-
Cornetta, K.1
-
37
-
-
85119465374
-
Development of antileukemia immunity using GM-CSF or B7.1 gene-transduced leukemia cells in vivo in mice
-
Tani K. Development of antileukemia immunity using GM-CSF or B7.1 gene-transduced leukemia cells in vivo in mice Blood 86 Suppl. 1 1995 1006a
-
(1995)
Blood
, vol.86
, Issue.Suppl. 1
, pp. 1006a
-
-
Tani, K.1
-
38
-
-
85119463455
-
Comparison of B7.1 and interleukin-2 (IL-2) in the rejection of a murine myeloid leukemia
-
Hirst W. Comparison of B7.1 and interleukin-2 (IL-2) in the rejection of a murine myeloid leukemia Blood 86 Suppl. 1 1995 414a
-
(1995)
Blood
, vol.86
, Issue.Suppl. 1
, pp. 414a
-
-
Hirst, W.1
-
39
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity,
-
Dranoff G. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity, Proc. Natl. Acad. Sci. U. S. A. 90 1993 3539 3543
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
-
40
-
-
0004643403
-
New IBMTR/ABMTR slides summarize current use and outcome of allogeneic and autologous transplants
-
Horowitz M.M. New IBMTR/ABMTR slides summarize current use and outcome of allogeneic and autologous transplants IBMTR Newsletter 2 1995 1 8
-
(1995)
IBMTR Newsletter
, vol.2
, pp. 1-8
-
-
Horowitz, M.M.1
-
41
-
-
0024988334
-
Gene transfer into humans — immunotherapy of patients with advanced melanoma, using tumor infiltrating lymphocytes modified by retroviral gene transduction
-
Rosenberg S.A. Gene transfer into humans — immunotherapy of patients with advanced melanoma, using tumor infiltrating lymphocytes modified by retroviral gene transduction New Engl. J. Med. 323 1990 570 578
-
(1990)
New Engl. J. Med.
, vol.323
, pp. 570-578
-
-
Rosenberg, S.A.1
-
43
-
-
0027443191
-
Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients
-
Brenner M.K. Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients Lancet 342 1993 1134 1137
-
(1993)
Lancet
, vol.342
, pp. 1134-1137
-
-
Brenner, M.K.1
-
44
-
-
0027471156
-
Gene-marking to trace origin of relapse after autologous bone-marrow transplantation
-
Brenner M.K. Gene-marking to trace origin of relapse after autologous bone-marrow transplantation Lancet 341 1993 85 86
-
(1993)
Lancet
, vol.341
, pp. 85-86
-
-
Brenner, M.K.1
-
45
-
-
85041132416
-
Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplant in CML
-
+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplant in CML Blood 83 1994 3068 3076
-
(1994)
Blood
, vol.83
, pp. 3068-3076
-
-
Deisseroth, A.B.1
-
46
-
-
0029924619
-
Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes
-
Heslop H.E. Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes Nat. Med. 2 1996 551 555
-
(1996)
Nat. Med.
, vol.2
, pp. 551-555
-
-
Heslop, H.E.1
-
47
-
-
0028094693
-
Gancyclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?
-
Tiberghien P. Gancyclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation? Blood 84 1994 1333 1341
-
(1994)
Blood
, vol.84
, pp. 1333-1341
-
-
Tiberghien, P.1
-
48
-
-
0010533576
-
Immunity against the transgene product may limit efficacy of HSV-Tk-transduced donor peripheral blood lymphocytes after allo-BMT
-
Bonini C. Immunity against the transgene product may limit efficacy of HSV-Tk-transduced donor peripheral blood lymphocytes after allo-BMT Blood 86 Suppl. 1 1995 628a
-
(1995)
Blood
, vol.86
, Issue.Suppl. 1
, pp. 628a
-
-
Bonini, C.1
-
49
-
-
0025362703
-
Expression of a human complementary DNA for the multidrug resistance gene in murine hemopoietic precursor cells with the use of retroviral gene transfer
-
McLachlin J.R. Expression of a human complementary DNA for the multidrug resistance gene in murine hemopoietic precursor cells with the use of retroviral gene transfer J. Natl. Cancer Inst. 82 1990 1260 1263
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1260-1263
-
-
McLachlin, J.R.1
-
50
-
-
0026637623
-
Selection of drug resistant bone marrow cells in vivo after retroviral transfer of human MDR1
-
Sorrentino B.P. Selection of drug resistant bone marrow cells in vivo after retroviral transfer of human MDR1 Science 257 1992 99 103
-
(1992)
Science
, vol.257
, pp. 99-103
-
-
Sorrentino, B.P.1
-
51
-
-
0026705269
-
Transfer and expression of the human multiple drug resistance gene into live mice
-
Podda S. Transfer and expression of the human multiple drug resistance gene into live mice Proc. Natl. Acad. Sci. U. S. A. 80 1992 9676 9682
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 9676-9682
-
-
Podda, S.1
|