Mutational analysis of Glu-327 of Na+-K+-ATPase reveals stimulation of 86Rb+ uptake by external K+

American Journal of Physiology - Cell Physiology

Volumn 273, Issue 6 42-6, 1997, Pages

  Tepperman, Katherine ^a   Millette, Lauren A ^a   Johnson, Carl L ^b   Jewell Motz, Elizabeth A ^b   Lingrel, Jerry B ^b   Wallick, Earl T ^b  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Mechanistic modeling; Mutagenesis; Potassium flux; Sodium pump; Transport

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); POTASSIUM ION; RUBIDIUM ION; SODIUM ION;

ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; MEMBRANE MODEL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; SODIUM TRANSPORT; TRANSPORT KINETICS;

STROPHANTHUS GRATUS;

EID: 0031408173     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.273.6.c2065     Document Type: Article

References (12)

1. Amorino, G. P., and M. H. Fox. Heat-induced changes in intracellular sodium and membrane potential: lack of a role in cell killing and thermotolerance. Rad. Res. 146: 283-292, 1996.
2. Arguello, J. M., and J. H. Kaplan. Glutamate 779, an intramembrane carboxyl, is essential for monovalent cation binding by the Na,K-ATPase. J. Biol. Chem. 269: 6892-6899, 1994.
3. Bahinski, A., M. Nakao, and D. Gadsby. Potassium translocation by the Na+/K+ is voltage insensitive. Proc. Natl. Acad. Sci. USA 85: 3412-3416, 1988.
4. Bell, M. V., F. Tonduer, and J. R. Sargent. The activation of sodium-plus-potassium ion-dependent adenosine triphosphatase from marine teleost gills by univalent cations. Biochem. J. 163: 185-187, 1977.
5. Buhler, R., and H.-J. Apell. Sequential potassium binding at the extracellular side of the Na,K-pump. J. Membr. Biol. 145: 165-173, 1995.
6. Cavieres, J. D., and J. C. Ellory. Allosteric inhibition of the sodium pump by external sodium. Nature 255: 338-340, 1975.
7. 2(+)-ATPase of sarcoplasmic reticulum. J. Biol. Chem. 265: 6262-6267, 1990.
8. Draper, N. R., and H. Smith. Applied Regression Analysis. New York: Wiley, 1966.
9. +-ATPase α subunit identifies threonine 797 as a determinant of ouabain sensitivity. Biochemistry 33: 4218-4224, 1994.
10. + movements in a single turnover of the Na/K pump. Curr. Top. Membr. Transp. 28: 19-39, 1987.
11. i or vanadate. J. Biol. Chem. 262: 11116-11127, 1987.
12. Garay, R. P., and P. J. Garrahan. The interaction of sodium and potassium with the sodium pump in red cells. J. Physiol. (Lond.) 231: 297-325, 1973.