Multiple nuclear proteins bind a novel cis-acting element that regulates the muscle-specific expression of the mouse nicotinic acetylcholine receptor α-subunit gene

DNA and Cell Biology

Volumn 16, Issue 9, 1997, Pages 1099-1110

  Dennis, Philip ^a   Prody, Catherine A ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; NICOTINIC RECEPTOR; NUCLEAR PROTEIN;

ANIMAL CELL; ARTICLE; CROSS LINKING; DNA PROBE; DNA PROTEIN COMPLEX; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION; METHYLATION; MOUSE; MYOBLAST; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE; TRANSCRIPTION REGULATION;

EID: 0031405248     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1997.16.1099     Document Type: Article

References (19)

1. ANDREWS, N.C., and FALLER, D.V. (1991). A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucl. Acids Res. 19, 2499.
2. AUSUBEL, R.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G., SMITH, J.A., and STRUHL, K. (1987). Current Protocols in Molecular Biology. J. Wiley and Sons, New York, Ch. 5.
3. BALDWIN, T.J., and BURDEN, S.J. (1988). Isolation and characterization of the mouse acetylcholine receptor delta subunit gene: Identification of a 148-bp cis-acting region that confers myotube-specific expression. J. Cell Biol. 107, 2271-2279.
4. BERBERICH, C., DÜRR, I., KOENEN, M., and WITZEMANN, V. (1993). Two adjacent E box elements and a M-CAT box are involved in the muscle-specific regulation of the rat acetylcholine receptor β subunit gene. Eur. J. Biochem. 216, 395-404.
5. BESSEREAU, J.L., MENDELZON, D., LEPOUPON, C., FISZMAN, M., CHANGEUX, J.P., and PIETTE, J. (1993). Muscle-specific expression of the acetylcholine receptor α-subunit gene requires both positive and negative interactions between myogenic factors, Sp1 and GBF factors. Embo J. 12, 443-449.
6. BESSEREAU, J.L., STRATFORD, P.L., PIETTE, J., LE, P.C., and CHANGEUX, J.P. (1994). In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus. Proc. Natl. Acad. Sci. USA 91, 1304-1308.
7. BRENNAN, T.J., and OLSON, E.N. (1990). Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization. Genes Dev. 4, 582-595.
8. BUONANNO, A., APONE, L., MORASSO, M.I., BEERS, R., BRENNER, H.R., and EFTIMIE, R. (1992). The MyoD family of myogenic factors is regulated by electrical activity. Nucl. Acids Res. 20, 539-544.
9. BUONANNO, A., and MERLIE, J.P. (1986). Transcriptional regulation of nicotinic acetylcholine receptor genes during muscle development. J. Biol. Chem. 261, 11452-11455.
10. CHAHINE, K.G., WALKE, W., and GOLDMAN, D. (1992). A 102 base pair sequence of the nicotinic acetylcholine receptor δ-subunit gene confers regulation by muscle electrical activity. Development 115, 213-219.
11. CHANGEUX, J.P. (1991). Compartmentalized transcription of acetylcholine receptor genes during motor endplate epigenesis. New Biologist 3, 413-429.
12. CROWDER, C.M., and MERLIE, J.P. (1988). Stepwise activation of the mouse acetylcholine receptor delta- and gamma-subunit genes in clonal cell lines. Mol. Cell. Biol. 8, 5257-5267.
13. DELWEL, R., FUNABIKI, T., KREIDER, B.L., MORISHITA, K., and IHLE, J.N. (1993). Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA. Mol. Cell. Biol. 13, 4291-4300.
14. DONOGHUE, M., ERNST, H., WENTWORTH, B., NADAL-GINARD, B., and ROSENTHAL, N. (1988). A muscle-specific enhancer is located at the 3′ end of the myosin light-chain 1/3 gene locus. Genes Dev. 2, 1779-1790.
15. DUCLERT, A., SAVATUERM, B., SCHAEFFER, L., and CHANGEUX, J.-P. (1996). Identification of an element crucial for the sub-synaptic expression of the acetylcholine receptor epsilon-subunit gene. J. Biol. Chem. 271, 17433-17438.
16. DUCLERT, A., and CHANGEUX, J.-P. (1995). Acetylcholine receptor gene expression at the developing neuromuscular junction. Physiol. Rev. 75, 339-368.
17. DURR, I., NUMBERGER, M., BERBERICH, C., and WITZEMANN, V. (1994). Characterization of the functional role of E-box elements for the transcriptional activity of rat acetylcholine receptor epsilon-subunit and gamma-subunit gene promoters in primary muscle cell cultures. Eur. J. Biochem. 224, 353-364.
18. DÜRR, I., NUMBERGER, M., BERBERICH, C., and WITZEMANN, V. (1994). Characterization of the functional role of E-box elements for the transcriptional activity of rat acetylcholine receptor ∈-subunit and γ-subunit gene promoters in primary muscle cell cultures. Eur. J. Biochem. 224, 353-364.
19. EFTIMIE, R., BRENNER, H.R., and BUONANNO, A. (1991). Myogenin and myoD join a family of skeletal muscle genes regulated by electrical activity. Proc. Natl. Acad. Sci. USA 88, 1349-1353.