Attachment of human uveal melanocytes and melanoma cells to extracellular matrix proteins involves intracellular calcium and calmodulin

Melanoma Research

Volumn 7, Issue 6, 1997, Pages 439-448

  Wagner, M ^a   Bielby, S ^a   Rennie, I G ^a   Mac Neil, S ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Calcium; Calmodulin; Extracellular matrix (ECM); Tamoxifen; Uveal melanocytes; Uveal melanoma cells

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CALCIUM; CALMODULIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; CYCLIC AMP; FIBRONECTIN; LAMININ; PROTEIN KINASE C; SCLEROPROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CELL ADHESION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; UVEA MELANOMA;

CALCIUM; CALMODULIN; CELL ADHESION; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; HUMANS; LAMININ; MELANOCYTES; MELANOMA; OLIGOPEPTIDES; TUMOR CELLS, CULTURED; UVEA; UVEAL NEOPLASMS;

EID: 0031404662     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008390-199712000-00001     Document Type: Article

References (21)

1. Sheilcls JA, Sheilds CL. Intraocular Tumours. Philadelphia, WB Saunders, 1992.
2. Deiner-West M, Hawkins BS, Markowitz JA, Schachat AP. A review of mortality from choroidal melanoma: II A meta-analysis of 5 year mortality rates following enucleation, 1966 through 1988. Arch Ophthalmol 1992; 110: 245-250.
3. Mortarini R, Anchini A. From adhesion to signalling: roles of integrins in the biology of human melanoma. Melanoma Res 1993; 3: 87-97.
4. Mac Neil S, Wagner M, Wbwk I, Doughty S, Brown J, Beaumont J, Blackburn J. Intracellular regulation of cell adhesion to extracellular matrix components in murine B16 melanoma cells of differing metastatic potential. Melanoma Res 1992; 2: 345-354.
5. Mac Neil S, Wagner M, Kirkham PR, Blanksom EA, Lennard MS, Goodall T, Rennie IG. Inhibition of melanoma cell/matrix interaction by tamoxifen. Melanoma Res 1993; 3: 67-74.
6. Mac Neil S, Wagner M, Rennie IG. Investigation of the role of signal transduction in attachment of ocular melanoma cells to matrix proteins; inhibition of attachment by calmodulin antagonists including tamoxifen. Clin Exp Metastasis 1994; 12: 375-384.
7. Smith TW, Menter DG, Nicholson GL, Mclntire LV. Regulation of melanoma cell adhesion stabilization to fibronectin. Melanoma Res 1996; 6: 351-362.
8. Lien EA, Solheim E, Ueland PM. Distribution of tamoxifen and its metabolites in rat and human tissues during steady state treatment. Cancer Res 1991; 51: 4837-4844.
9. Cocconi G, Bella M, Calabresi F, et al. Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen. NEnglJMed 1992; 327: 516-523.
10. Dewhurst LO, Gee JW, Rennie IG, Mac Neil S. Tamoxifen, 17ß-oestradiol and the calmodulin antagonist J8 inhibit human melanoma cell invasion through fibronectin. BrJ Cancer 1997; 75: 860-868.
11. MacNeil S, Griffin M, Cooke AM, Pettett NJ, Dawson RA, Owen R, Blackburn GM. Calmodulin antagonists of improved potency and specificity for use in the study of calmodulin biochemistry. Btocbem Pharinacol 1988; 37: 1717-1723.
12. Wagner M, Benson MT, Rennie IG, MacNeÜ S. Effects of pharmacological modulation of intracellular signalling systems on retinal pigment epithelial cell attachment to extracellular matrix proteins. Ctirr Eye Res 1995; 14: 373-384.
13. Goodall T, Buffey JA, Rennie IG, Benson M, Parsons MA, Faulkner MK, MacNeil S. Effect of melanocyte stimulating hormone on human cultured choroidal melanocytes, uveal melanoma cells and retinal epithelial cells. Invest Opbthalmol Vis Sci 1994; 35: 826-837.
14. Ye QL, Wagner M, Smythe S, MacNeil S. Thyrotrophin, but not forskolin, increases intracellular free calcium and calmodulin in pig thyroid cells. / Endocrinol 1991; 129: 291-299.
15. Ealey PA, Yateman ME, Holt SJ, Marshall NJ. ESTA: a bioassay system for the determination of the potencies of hormones and antibodies which mimic their action. J Mol Endocrinol 1988; 1: R1-R4.
16. Gilchrest BA, Albert LS, Karassik RL, Yaar M. Substrate influences human epidermal melanocyte attachment and spreading in vitro. In Vitro Cell Dev Biol 1985; 21: 114-120.
17. Dänen EHJ, Van Muijen GNP, Van de Wiel-Van Kemade Z, Janen KFJ, Ruiter DJ, Figdor CG. Regulation of integrin-mediated adhesion to laminin and collagen in human melanocyte and in non-metastatic and highly metastatic human melanoma cells. IntJ Cancer 1993; 54: 315-321.
18. Scott G, Ryan DH, McCarthy JB. Molecular mechanisms of human melanocyte attachment to fibronectin. J Invest Dcnnatol 1992; 99: 787-794.
19. Buffey JA, Hill SE, Blechen SS, Thody AJ, MacNeil S. Evidence for a calcium/calmodulin involvement in density-dependent melanogenesis in murine Bl6 melanoma cells. Pigment Cell Res 1991; 4: 112-119.
20. Savarese DM, Russell JT, Fatatis A, Liotta' A. Type IV collagen stimulates an increase in intracellular calcium. Potential role in tumour cell motility. / Biol Chein 1992; 267: 21928-21935.
21. Parsons PG, Musk P, Goss PD, Leah J. Effects of calcium depletion of human cells in vitro and the anomalous behaviour of the human melanoma cell line MM170. Cancer Res 1983; 43: 2081- 2087.