Chronic Ulcerative Typhlocolitis in CBH-rnu/rnu (Athymic Nude) Rats

Laboratory Animal Science

Volumn 47, Issue 4, 1997, Pages 423-427

  Thomas, Darren S ^a   Pass, David A ^a  

^a Animal Resources Centre   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BACTERIUM CULTURE; CLINICAL FEATURE; COLON BIOPSY; DIARRHEA; HISTOPATHOLOGY; HOMOZYGOSITY; NONHUMAN; NUDE MOUSE; OCCULT BLOOD; RAT; TYPHOID FEVER; ULCERATIVE COLITIS;

ANIMALS; CHRONIC DISEASE; COLITIS, ULCERATIVE; FEMALE; INTESTINE, LARGE; MALE; PERINEUM; PREVALENCE; RATS; RATS, NUDE; RODENT DISEASES; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 0031402890     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Barker, I. K., A. A. Van Dreumel, and N. Palmer. 1993. The alimentary system, 4th ed., p. 125-133. In K. V. F. Jubb, P. C. Kennedy, and N. Palmer (ed.), Pathology of domestic animals. Academic Press, Inc., San Diego, Calif.
2. Madara, J. L., D. K. Podolsky N. W. King, et al. 1985. Characterization of spontaneous colitis in cotton top tamarins (Saguinus oedipus) and its response to sulfasalazine. Gastroenterology 88:13-9.
3. Sundberg, J. P., C. O. Elson, H. Bedigian, et al. 1994. Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice. Gastroenterology 107:1726-1735.
4. Umemura, T., M. Tsuchitani, M. Totsuka, et al. 1982. Histiocytic enteritis of rabbits. Vet. Pathol. 19:326-329.
5. Podolsky, D. K. 1991. Inflammatory bowel disease. N. Engl. J. Med. 325:928-937.
6. Ward, J. M., M. R. Anver, D. C. Haines, et al. 1996. Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus. Lab. Anim. Sci. 46:15-20.
7. Hammer, R. E., S. D. Maika, J. A. Richardson, et al. 1990. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human ß2m: an animal model of HLA-B27-associated human disorders. Cell 63:1099-1112.
8. Sadlack, B., H. Merz, H. Schorlg, et al. 1993. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75:253-261.
9. Kuhn, R., J. Lohler, D. Rennick, et al. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263-274.
10. Mombaerts, P., E. Mizogurhi, M. J. Grusby, et al. 1993. Spontaneous development of inflammatory bowel disease in T-cell receptor mutant mice. Cell 75:275-282.
11. Andrews, E. J., B. T. Bennett, J. D. Clark, et al. 1993. Report of the AVMA panel on euthanasia. J. Am. Vet. Med. Assoc. 202:230-249.
12. Strober, W., and R. O. Ehrhardt. 1993. Chronic intestinal inflammation. An unexpected outcome in cytokine or T-cell receptor mutant mice. Cell 75:203-205.
13. N (nznu, New Zealand nude) rat: an update. ILAR News 34:3-12.
14. Vaessen, C. M. B., R. Broekhuizen, J. Rozing, et al. 1986. T-cell development during ageing in congenitally athymic (nude) rats. Scand. J. Immunol. 24:223-235.
15. Carthew, P., and S. Sparrow. 1980. Sendai virus in nude and germfree rats. Res. Vet. Sci. 29:289-292.
16. Festing, M. F. W. 1981. Athymic nude rats, p. 267-283. In M. E. Gershwin and B. Merchant (ed.), Immunological defects in laboratory animals. Plenum Press, New York.
17. Ziefer, A., T. Jacobs, H. J. Hedrich, et al. 1984. Pneumocystis carinii-infections in immunosuppressed and in thymus-deficient rats. Zentralbl. Bakteriol. A 258:387.
18. Thunert, A. L., L. C. Jonas, S. Rehn, et al. 1985 Transmission and course of Tyzzer's disease in euthymic and thymus aplastic nude Han:RNU rats. Z. Versuchstierk 27:241-248.
19. Videla, S., J. Vilaseca, F. Guarner, et al. 1994. Role of intestinal microflora in chronic inflammation and ulceration of the rat colon. Gut 35:1090-1097.