Role of H-ras gene in chronic liver damage in mice, by using transgenic mice carrying a human c-H-ras protogene without mutations

Biochemistry and Molecular Biology International

Volumn 42, Issue 2, 1997, Pages 371-379

  Tsunematsu, Satoshi ^a   Saito, Hidetsugu ^b   Sato, Reiko ^c   Morizane, Toshio ^a   Ishii, Hiromasa ^b  

^a KANAGAWA DENTAL COLLEGE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c NONE

Author keywords

H ras; Hepatocellular caricmona; Neoplastic nodule; Over expression; Point mutation

Indexed keywords

CARBON TETRACHLORIDE; PROTEIN P21; RAS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER CELL CARCINOMA; LIVER INJURY; LIVER TUMOR; NONHUMAN; ONCOGENE H RAS; POINT MUTATION; PROTO ONCOGENE; TRANSGENIC MOUSE;

ANIMALS; CARBON TETRACHLORIDE; CARCINOMA, HEPATOCELLULAR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; RAS PROTEINS;

EID: 0031401930     PISSN: 10399712     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Reynolds, S.H., Stowers, S.J., Patterson, R.M., Maronpot, R.R., Aaronson, S.A., and Anderson, M.W. (1987) Science. 237, 1309-1317.
2. Tsunematsu, S., Saito, H., Kagawa, T., Morizane, T., Hata, J., Nakamura, T., Ishii, H., Tsuchiya, M., Nomura, T., and Katsuki, M. (1994) Int. J. Cancer. 59, 554-559.
3. Kanai, T., Hirohashi, S., Noguchi, M., Shinoyama, Y., Shimosato, Y., Noguchi, S., Nishimura, S., and Abe, O. (1994) Jpn. J. Cancer Res. 87, 1314-1318.
4. Saitoh, A., Kimura, M., Takahashi, R., Yokoyama, M., Nomura, T., Izawa, M., Sekiya, T., Nishimura, S., and Katsuki, M. (1990) Oncogene. 5, 1195-1200.
5. Mangues, R., Seidman, I., Gordon, J. W., and Pellicer, A. (1992) Oncogene. 7, 2023-2076.
6. Suzuki, K., Hayashi, N., Yamada, Y., Yoshihara, H., Miyamoto, Y., Ito, Y., Ito, T., Katayama, K., Sasaki, Y., Ito, A., Kishida, Y., Kashiwagi, T., Fusamoto, H., and Kameda,T. (1994) Hepatology. 20, 1231-1236.
7. Chang, E.H., Furth, M.E., Scolnick, E.M., and Lowy, D.R. (1982) Nature (Lond). 297, 479-483.
8. Ricketts, S.H., and Levinson, A.D. (1988) Science. 237, 1309-1317, 1988.
9. Muller, R., Salmon, D. J., Tremblay, J. M., Cline, M. J, Verma, I. M. (1982) Nature. 299, 640-644.
10. Salmon, D. J., and Cline, M. J. (1984) Proc. Natl. Acad. Sci. USA. 83, 33-37.
11. Leon, J., Guerrero, I., and Pellicer A. (1987) Mol. Cell. Biol., 7: 1535-1540.
12. Katsuki, M., Kimura, M., Hata, J., Takahashi, R., Nozaawa, S., and Nomura, T. (1989) Mol. Biol. Med. 6, 567-572.
13. Inoue, R., Ushijima, T., Katami, M., Kushida, H., Wakabayashi, K., Sato, H., Asamoto, M., Katsuki, M., Sugimura, T., and Nagao, M. (1996) Jpn. J. Cancer Res. 87, 583-588.
14. Pasquinelli, C., Bhavani, K., and Chiari, F. V. Cancer Res. (1992) 52, 2823-2829.