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Volumn 67, Issue SUPPL. 28/29, 1997, Pages 81-89

Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene

Author keywords

Benzo (a)pyrene; Chemoprevention; Difluoromethylornithine; Skin tumor markers; Squamous cell carcinoma

Indexed keywords

ACETONE; BENZO[A]PYRENE; DRUG VEHICLE; EFLORNITHINE; CARCINOGEN;

EID: 0031401901     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(1997)28/29+<81::AID-JCB9>3.0.CO;2-S     Document Type: Article
Times cited : (16)

References (34)
  • 1
    • 84965819978 scopus 로고
    • The histogenesis of benzopyrene-induced epidermal tumors in the mouse
    • Glucksmann A (1945): The histogenesis of benzopyrene-induced epidermal tumors in the mouse. Cancer Res 5:385-400.
    • (1945) Cancer Res , vol.5 , pp. 385-400
    • Glucksmann, A.1
  • 3
    • 0027500049 scopus 로고
    • Benzo(a)-pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene
    • Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T, Klein-Szanto AJP (1994): Benzo(a)-pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci USA 90:1013-1017.
    • (1994) Proc Natl Acad Sci USA , vol.90 , pp. 1013-1017
    • Ruggeri, B.1    DiRado, M.2    Zhang, S.Y.3    Bauer, B.4    Goodrow, T.5    Klein-Szanto, A.J.P.6
  • 4
    • 0029072602 scopus 로고
    • Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo(a)pyrene
    • Mitsunaga SI, Zhang SY, Ruggeri BA, Gimenez-Conti I, Robles AI, Conti CJ, Klein-Szanto AJP (1995): Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo(a)pyrene. Carcinogenesis 16:1629-1635.
    • (1995) Carcinogenesis , vol.16 , pp. 1629-1635
    • Mitsunaga, S.I.1    Zhang, S.Y.2    Ruggeri, B.A.3    Gimenez-Conti, I.4    Robles, A.I.5    Conti, C.J.6    Klein-Szanto, A.J.P.7
  • 5
    • 0024325267 scopus 로고
    • Inhibition of 7,12-dimethylbenz(a)anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs
    • Schwartz AG, Fairman DK, Polansky M, Lewbart ML, Pashko LL (1989): Inhibition of 7,12-dimethylbenz(a)anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs. Carcinogenesis 10:1809-1813.
    • (1989) Carcinogenesis , vol.10 , pp. 1809-1813
    • Schwartz, A.G.1    Fairman, D.K.2    Polansky, M.3    Lewbart, M.L.4    Pashko, L.L.5
  • 6
    • 0024595055 scopus 로고
    • Tumor prevention by a xanthate compound in experimental mouse-skin tumorigenesis
    • Furstenberger G, Amtmann E, Marks F, Sauer G (1989): Tumor prevention by a xanthate compound in experimental mouse-skin tumorigenesis. Int J Cancer 43:508-512.
    • (1989) Int J Cancer , vol.43 , pp. 508-512
    • Furstenberger, G.1    Amtmann, E.2    Marks, F.3    Sauer, G.4
  • 7
    • 0026448684 scopus 로고
    • Potent preventive action of a-carotene against carcinogenesis: Spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by α-carotene than by β-carotene
    • Murakoshi M, Nishino H, Satomi Y, Takayasu J, Hasegawa T, Tokuda H, Iwashima A, Okuzumi J, Okabe H, Kitano H, Iwasaki R (1992): Potent preventive action of a-carotene against carcinogenesis: Spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by α-carotene than by β-carotene. Cancer Res 52:6583-6587.
    • (1992) Cancer Res , vol.52 , pp. 6583-6587
    • Murakoshi, M.1    Nishino, H.2    Satomi, Y.3    Takayasu, J.4    Hasegawa, T.5    Tokuda, H.6    Iwashima, A.7    Okuzumi, J.8    Okabe, H.9    Kitano, H.10    Iwasaki, R.11
  • 8
    • 0027223528 scopus 로고
    • Differential effects of dietary β-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin
    • Chen L-C, Sly L, Jones CS, Tarone R, DeLuca LM (1993): Differential effects of dietary β-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin. Carcinogenesis 14:713-717.
    • (1993) Carcinogenesis , vol.14 , pp. 713-717
    • Chen, L.-C.1    Sly, L.2    Jones, C.S.3    Tarone, R.4    DeLuca, L.M.5
  • 9
    • 0027243119 scopus 로고
    • Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation
    • Strickland JE, Dlugosz AA, Hennings H, Yuspa SH (1993): Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation. Carcinogenesis 14:205-209.
    • (1993) Carcinogenesis , vol.14 , pp. 205-209
    • Strickland, J.E.1    Dlugosz, A.A.2    Hennings, H.3    Yuspa, S.H.4
  • 10
    • 0028212758 scopus 로고
    • Effects of dietary selenium on UVB-induced skin carcinogenesis and epidermal antioxidant status
    • Pence BC, Delver E, Dunn DM (1994): Effects of dietary selenium on UVB-induced skin carcinogenesis and epidermal antioxidant status. J Invest Dermatol 102:759-761.
    • (1994) J Invest Dermatol , vol.102 , pp. 759-761
    • Pence, B.C.1    Delver, E.2    Dunn, D.M.3
  • 11
    • 0009379698 scopus 로고
    • Protein kinase C and skin cancer prevention
    • Mukhtar H (ed): Boca Raton, FL: CRC Press
    • Verma AK (1995): Protein kinase C and skin cancer prevention. In Mukhtar H (ed): "Skin Cancer: Mechanisms and Human Relevance." Boca Raton, FL: CRC Press, pp 382-390.
    • (1995) Skin Cancer: Mechanisms and Human Relevance , pp. 382-390
    • Verma, A.K.1
  • 12
    • 0344441081 scopus 로고
    • Skin cancer chemoprevention by naturally occurring polyphenols
    • Mukhtar H (ed): Boca Raton, FL: CRC Press
    • Agarwal R, Katiyar SK, Mukhtar H (1995): Skin cancer chemoprevention by naturally occurring polyphenols. In Mukhtar H (ed): "Skin Cancer: Mechanisms and Human Relevance." Boca Raton, FL: CRC Press, pp 391-400.
    • (1995) Skin Cancer: Mechanisms and Human Relevance , pp. 391-400
    • Agarwal, R.1    Katiyar, S.K.2    Mukhtar, H.3
  • 13
    • 0008234636 scopus 로고
    • Retinoid effects on skin cancer
    • Mukhtar H (ed): Boca Raton, FL: CRC Press
    • Chen L-C, DeLuca LM (1995): Retinoid effects on skin cancer. In Mukhtar H (ed): "Skin Cancer: Mechanisms and Human Relevance." Boca Raton, FL: CRC Press, pp 401-426.
    • (1995) Skin Cancer: Mechanisms and Human Relevance , pp. 401-426
    • Chen, L.-C.1    DeLuca, L.M.2
  • 14
    • 0020215250 scopus 로고
    • Polyamine metabolism and function
    • Pegg AE, McCann PP (1982): Polyamine metabolism and function. Am J Physiol 243:C212-C221.
    • (1982) Am J Physiol , vol.243
    • Pegg, A.E.1    McCann, P.P.2
  • 15
    • 0024306523 scopus 로고
    • The enzyme-activated irreversible inhibitor of ornithine decarboxylase, D,L-α-difluoromethylornithine: A chemopreventive agent
    • Verma AK (1989): The enzyme-activated irreversible inhibitor of ornithine decarboxylase, D,L-α-difluoromethylornithine: A chemopreventive agent. Prev Med 18:646-652.
    • (1989) Prev Med , vol.18 , pp. 646-652
    • Verma, A.K.1
  • 16
    • 0022450919 scopus 로고
    • Recent advances in the biochemistry of polyamines in eukaryotes
    • Pegg AE (1986): Recent advances in the biochemistry of polyamines in eukaryotes. Biochem J 234:249-262.
    • (1986) Biochem J , vol.234 , pp. 249-262
    • Pegg, A.E.1
  • 17
    • 0017072855 scopus 로고
    • The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis
    • O'Brien TG (1976): The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis. Cancer Res 36:2644-2653.
    • (1976) Cancer Res , vol.36 , pp. 2644-2653
    • O'Brien, T.G.1
  • 18
    • 0021876947 scopus 로고
    • In vitro induction of human skin ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
    • Verma AK, Loprinzi CL, Boutwell RK, Carbone PP (1985): In vitro induction of human skin ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. JNCI 75:85-90.
    • (1985) JNCI , vol.75 , pp. 85-90
    • Verma, A.K.1    Loprinzi, C.L.2    Boutwell, R.K.3    Carbone, P.P.4
  • 19
    • 0000382583 scopus 로고
    • α-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin
    • Weeks CE, Herrmann AL, Nelson FR, Slaga TJ (1982): α-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin. Proc Natl Acad Sci USA 79:6032-6032.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 6032-6032
    • Weeks, C.E.1    Herrmann, A.L.2    Nelson, F.R.3    Slaga, T.J.4
  • 20
    • 0020605877 scopus 로고
    • Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by α-difluoromethylornithine
    • Takigawa M, Verma AK, Simsiman RC, Boutwell RK (1983): Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by α-difluoromethylornithine. Cancer Res 43:3732-3738.
    • (1983) Cancer Res , vol.43 , pp. 3732-3738
    • Takigawa, M.1    Verma, A.K.2    Simsiman, R.C.3    Boutwell, R.K.4
  • 21
    • 0027502198 scopus 로고
    • Chemoprevention of oral carcinogenesis by D,L-α-difluoromethylornithine, an ornithine decarboxylase inhibitor: Dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats
    • Tanaka T, Kojima T, Hara A, Sawada H, Mori H (1993): Chemoprevention of oral carcinogenesis by D,L-α-difluoromethylornithine, an ornithine decarboxylase inhibitor: Dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats. Cancer Res 53:772-776.
    • (1993) Cancer Res , vol.53 , pp. 772-776
    • Tanaka, T.1    Kojima, T.2    Hara, A.3    Sawada, H.4    Mori, H.5
  • 22
    • 0025270332 scopus 로고
    • Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a non-steroidal anti-inflammatory drug with D,L-α-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet
    • Reddy B, Nayini J, Tokumo K, Rigotty J, Zang E, Kelloff G (1990): Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a non-steroidal anti-inflammatory drug with D,L-α-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet. Cancer Res 50:2562-2568.
    • (1990) Cancer Res , vol.50 , pp. 2562-2568
    • Reddy, B.1    Nayini, J.2    Tokumo, K.3    Rigotty, J.4    Zang, E.5    Kelloff, G.6
  • 23
    • 0025999819 scopus 로고
    • Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, a-difluoromethylornithine, 16-a-fluoro-5-androsten-17-one, and ellagic acid individually and in combination
    • Rao CV, Tokumo K, Rigotty J, Zang E, Kelloff G, Reddy BS (1991): Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, a-difluoromethylornithine, 16-a-fluoro-5-androsten-17-one, and ellagic acid individually and in combination. Cancer Res 51: 4528-4534.
    • (1991) Cancer Res , vol.51 , pp. 4528-4534
    • Rao, C.V.1    Tokumo, K.2    Rigotty, J.3    Zang, E.4    Kelloff, G.5    Reddy, B.S.6
  • 24
    • 0027212971 scopus 로고
    • Intermediate biomarkers of colon cancer: Modulation of expression of ras oncogene by chemopreventive agents during azoxymethane induced colon carcinogenesis
    • Singh J, Kelloff G, Reddy BS (1993): Intermediate biomarkers of colon cancer: Modulation of expression of ras oncogene by chemopreventive agents during azoxymethane induced colon carcinogenesis. Carcinogenesis 14:699-704.
    • (1993) Carcinogenesis , vol.14 , pp. 699-704
    • Singh, J.1    Kelloff, G.2    Reddy, B.S.3
  • 25
    • 0027517497 scopus 로고
    • Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumors formation in rats fed a fiber-free diet
    • McGarity T, Peiffer LP (1993): Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumors formation in rats fed a fiber-free diet. Carcinogenesis 14:2335-2340.
    • (1993) Carcinogenesis , vol.14 , pp. 2335-2340
    • McGarity, T.1    Peiffer, L.P.2
  • 27
    • 0023485265 scopus 로고
    • Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by a-fluoromethylornithine
    • Homma Y, Kakizoe T, Samma S, Oyasu R (1987): Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by a-fluoromethylornithine. Cancer Res 47:6176-6179.
    • (1987) Cancer Res , vol.47 , pp. 6176-6179
    • Homma, Y.1    Kakizoe, T.2    Samma, S.3    Oyasu, R.4
  • 28
    • 0020601858 scopus 로고
    • Effects of a-difluoromethylornithine on the growth of experimental Wilms' tumors and renal adenocarcinoma
    • Kingsnorth AN, McCann PP, Diekema KA, Ross JS, Malt RA (1983): Effects of a-difluoromethylornithine on the growth of experimental Wilms' tumors and renal adenocarcinoma. Cancer Res 43:4031-4034.
    • (1983) Cancer Res , vol.43 , pp. 4031-4034
    • Kingsnorth, A.N.1    McCann, P.P.2    Diekema, K.A.3    Ross, J.S.4    Malt, R.A.5
  • 29
    • 0027293948 scopus 로고
    • Chemopreventive effects of dietary D,L-a-difluoromethylornithine, an ornithine decarboxylase inhibitor, on initiation and postinitiation stages of diethylnitrosamine-induced rat hepatocarcinogenesis
    • Kojima T, Tanaka T, Kawamori T, Kara A, Mori H (1993): Chemopreventive effects of dietary D,L-a-difluoromethylornithine, an ornithine decarboxylase inhibitor, on initiation and postinitiation stages of diethylnitrosamine-induced rat hepatocarcinogenesis. Cancer Res 53:3903-3907.
    • (1993) Cancer Res , vol.53 , pp. 3903-3907
    • Kojima, T.1    Tanaka, T.2    Kawamori, T.3    Kara, A.4    Mori, H.5
  • 32
    • 0027598093 scopus 로고
    • Urinary and erythrocyte polyamines during the evaluation of oral a-difluoromethylornithine in a Phase I chemoprevention clinical trial
    • Pendyala L, Creaven PJ, Porter CW (1993): Urinary and erythrocyte polyamines during the evaluation of oral a-difluoromethylornithine in a Phase I chemoprevention clinical trial. Cancer Epidemiol Biomark Prev 2:235-241.
    • (1993) Cancer Epidemiol Biomark Prev , vol.2 , pp. 235-241
    • Pendyala, L.1    Creaven, P.J.2    Porter, C.W.3
  • 34
    • 0027793114 scopus 로고
    • Intraepithelial and postinvasive neoplasia as a stochastic continuum of clonal evolution, and its relationship to mechanisms of chemopreventive drug action
    • Boone CW, Kelloff GJ, Freedman LS (1993): Intraepithelial and postinvasive neoplasia as a stochastic continuum of clonal evolution, and its relationship to mechanisms of chemopreventive drug action. J Cell Biochem 17G:14-25.
    • (1993) J Cell Biochem , vol.17 G , pp. 14-25
    • Boone, C.W.1    Kelloff, G.J.2    Freedman, L.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.