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Volumn 43, Issue 3, 1997, Pages 273-281

Serotonin antagonists for use as antiglaucoma agents and their ocular penetration

Author keywords

Absorption; Antiglaucoma agents; Distribution; Intraocular pressure; Permeability coefficients; Rabbits; Serotonin antagonists

Indexed keywords

1 PHENYLPIPERAZINE DERIVATIVE; 1 PHENYLPIPERIDINE; ANTIGLAUCOMA AGENT; DIETHYLAMINE; DRUG CARRIER; KETANSERIN; MORPHOLINE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

EID: 0031401881     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(97)00055-6     Document Type: Article
Times cited : (4)

References (22)
  • 1
    • 0027185041 scopus 로고
    • Topical application of serotonin or the 5-HT1-agonist 5-CT intraocular pressure in rabbits
    • U. Meyer-Bothling, A.J. Bron, N.N. Osborne, Topical application of serotonin or the 5-HT1-agonist 5-CT intraocular pressure in rabbits. Inv. Ophthalmol. Vis. Sci., 34 (1993) 3035-3042.
    • (1993) Inv. Ophthalmol. Vis. Sci. , vol.34 , pp. 3035-3042
    • Meyer-Bothling, U.1    Bron, A.J.2    Osborne, N.N.3
  • 2
    • 0023121581 scopus 로고
    • Characterization of serotonin receptors in the iris + ciliary body of the albino rabbit
    • P. Mallorga, M.F. Sugrue, Characterization of serotonin receptors in the iris + ciliary body of the albino rabbit, Curr. Eye Res., 6 (1987) 527-532.
    • (1987) Curr. Eye Res. , vol.6 , pp. 527-532
    • Mallorga, P.1    Sugrue, M.F.2
  • 4
    • 0025822073 scopus 로고
    • Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients
    • C. Costagliola, G. Scibelli, M.L. Fasano, L.A. Ferrara, L. Mastropassqua, Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients. Exp. Eye Res., 52 (1991) 507-510.
    • (1991) Exp. Eye Res. , vol.52 , pp. 507-510
    • Costagliola, C.1    Scibelli, G.2    Fasano, M.L.3    Ferrara, L.A.4    Mastropassqua, L.5
  • 6
    • 0001856781 scopus 로고
    • The Molecular Pharmacology of 5-Hydroxytryptamine Receptor Subtypes
    • Wiley-Liss, New York
    • S.J. Peroutka, The Molecular Pharmacology of 5-Hydroxytryptamine Receptor Subtypes. In: Serotonin Receptor Subtypes: Basic and Clinical Aspects. Wiley-Liss, New York, 1991, pp. 65-80.
    • (1991) Serotonin Receptor Subtypes: Basic and Clinical Aspects , pp. 65-80
    • Peroutka, S.J.1
  • 7
    • 0023723116 scopus 로고
    • Evidence for the presence of serotonergic nerves and receptors in the iris-ciliary body complex of the rabbit
    • A.B. Tobin, W. Unger, N.N. Osborne, Evidence for the presence of serotonergic nerves and receptors in the iris-ciliary body complex of the rabbit. J. Neurosci., 8 (1988) 3713-3721.
    • (1988) J. Neurosci. , vol.8 , pp. 3713-3721
    • Tobin, A.B.1    Unger, W.2    Osborne, N.N.3
  • 8
    • 0023547656 scopus 로고
    • Effect of serotonin and its antagonist (keranserin) on intraocular pressure in the rabbit
    • Krootila, K., Palkama, A., Uusitalo, H., Effect of serotonin and its antagonist (keranserin) on intraocular pressure in the rabbit. J. Ocular Pharmacol., 3 (1987) 279-290.
    • (1987) J. Ocular Pharmacol. , vol.3 , pp. 279-290
    • Krootila, K.1    Palkama, A.2    Uusitalo, H.3
  • 9
    • 0027304897 scopus 로고
    • The Presence of serotonin (5-HT1) receptors negatively coupled to adenylate cyclase in rabbit and human iris-ciliary processes
    • N.L. Barnett, N.N. Osborne, The Presence of serotonin (5-HT1) receptors negatively coupled to adenylate cyclase in rabbit and human iris-ciliary processes. Exp. Eye Res., 57 (1993) 209-216.
    • (1993) Exp. Eye Res. , vol.57 , pp. 209-216
    • Barnett, N.L.1    Osborne, N.N.2
  • 10
    • 0027082075 scopus 로고
    • Ketanserin analogues: Structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding
    • J.L. Herndon, S.P. Ismaiel, Ingher, M. Teitler, R.A. Glennon, Ketanserin analogues: Structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding. J. Med. Chem. 35 (1992) 4903-4910.
    • (1992) J. Med. Chem. , vol.35 , pp. 4903-4910
    • Herndon, J.L.1    Ismaiel, S.P.2    Ingher3    Teitler, M.4    Glennon, R.A.5
  • 11
    • 0022224440 scopus 로고
    • Mechanism of the ocular hypotensive action of ketanserin
    • F.W. Chang, J.S. Burke, D.E. Potter, Mechanism of the ocular hypotensive action of ketanserin. J. Ocular. Pharmacol., 1 (1985) 137-147.
    • (1985) J. Ocular. Pharmacol. , vol.1 , pp. 137-147
    • Chang, F.W.1    Burke, J.S.2    Potter, D.E.3
  • 12
    • 0023903510 scopus 로고
    • 5-Hydroxytryptamine receptor subtypes
    • S.J. Peroutka, 5-Hydroxytryptamine receptor subtypes. Ann. Rev. Neurosci., 11 (1988) 45-60.
    • (1988) Ann. Rev. Neurosci. , vol.11 , pp. 45-60
    • Peroutka, S.J.1
  • 13
    • 0007007656 scopus 로고
    • Serotonin modulators and cardiovascular gastrointestinal diseases
    • J.E. Audia, M.L. Cohen, Serotonin modulators and cardiovascular gastrointestinal diseases. Annual Report in Medicinal Chemistry, 26 (1991) 103-112.
    • (1991) Annual Report in Medicinal Chemistry , vol.26 , pp. 103-112
    • Audia, J.E.1    Cohen, M.L.2
  • 15
    • 26844446817 scopus 로고
    • Appendix I
    • Purcell, W.P., Bass G.E., Clayton, G.M. (Eds.), Wiley, New York
    • C. Hansch, Appendix I, in: Purcell, W.P., Bass G.E., Clayton, G.M. (Eds.), Strategy of Drug Design, Wiley, New York, 1973.
    • (1973) Strategy of Drug Design
    • Hansch, C.1
  • 16
    • 0021996783 scopus 로고
    • Topical Carbonic anhydrase inhibitors III: Optimization model for corneal penetration of ethoxzolamide analogues
    • M.G. Eller, R.D. Schoenwald, J.A. Dixson, Segarra, C.F. Barfknecht, Topical Carbonic anhydrase inhibitors III: Optimization model for corneal penetration of ethoxzolamide analogues. J. Pharm. Sci., 74 (1985) 155-160.
    • (1985) J. Pharm. Sci. , vol.74 , pp. 155-160
    • Eller, M.G.1    Schoenwald, R.D.2    Dixson, J.A.3    Segarra4    Barfknecht, C.F.5
  • 17
    • 0023789830 scopus 로고
    • Permeability of human cornea and sclera to sulfonamide carbonic anhydrase inhibitors
    • H.F. Edelhauser, T.H. Maren, Permeability of human cornea and sclera to sulfonamide carbonic anhydrase inhibitors, Arch. Ophthalmol., 106 (1988) 1110-1115.
    • (1988) Arch. Ophthalmol. , vol.106 , pp. 1110-1115
    • Edelhauser, H.F.1    Maren, T.H.2
  • 18
    • 0025775370 scopus 로고
    • Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: A comparison with comeal penetration
    • W. Wang, H. Sasaki, D.S. Chien, Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with comeal penetration. Curr. Eye Res., 10 (1991) 571-579.
    • (1991) Curr. Eye Res. , vol.10 , pp. 571-579
    • Wang, W.1    Sasaki, H.2    Chien, D.S.3
  • 19
    • 0029097601 scopus 로고
    • Different effects of absorption on corneal and conjunctival penetration of ophthalmic beta-blockers
    • S. Hitoshi, Y. Igarashi, T. Nagono, K. Nishida, J. Nakamura, Different effects of absorption on corneal and conjunctival penetration of ophthalmic beta-blockers, Pharm. Res., 12 (1995) 1146-1150.
    • (1995) Pharm. Res. , vol.12 , pp. 1146-1150
    • Hitoshi, S.1    Igarashi, Y.2    Nagono, T.3    Nishida, K.4    Nakamura, J.5
  • 20
    • 0019350144 scopus 로고
    • Effect of timolol on aqueous humor dynamics in the rabbit
    • P. Vareilles, V.J. Lotti, Effect of timolol on aqueous humor dynamics in the rabbit. Ophthalmic Res., 13 (1981) 72-77.
    • (1981) Ophthalmic Res. , vol.13 , pp. 72-77
    • Vareilles, P.1    Lotti, V.J.2
  • 21
    • 0013675657 scopus 로고
    • Chemical delivery systems with enhanced phar nacokinetic properties
    • Mitra, A.K., (Ed.) Marcel Dekker, New York
    • R.D. Schoenwald, Chemical delivery systems with enhanced phar nacokinetic properties, in: Mitra, A.K., (Ed.) Ophthalmic Drug Delivery Systems. Marcel Dekker, New York, 1993. pp. 307-330.
    • (1993) Ophthalmic Drug Delivery Systems , pp. 307-330
    • Schoenwald, R.D.1
  • 22
    • 0343955301 scopus 로고
    • Stuctural considerations of the sclera
    • Springer, New York
    • C.S. Foster, M.S. de la Maza, Stuctural considerations of the sclera, in: The Sclera, Springer, New York, 1994, pp. 10-32.
    • (1994) The Sclera , pp. 10-32
    • Foster, C.S.1    De La Maza, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.