Perfusion-weighted MRI using gadobutrol as a contrast agent in a rat stroke model

Journal of Magnetic Resonance Imaging

Volumn 7, Issue 6, 1997, Pages 1109-1115

  Heiland, Sabine ^a   Benner, Thomas ^a   Reith, Wolfgang ^a   Forsting, Michael ^a   Sartor, Klaus ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Animal studies; Cerebral ischemia; Contrast media; Paramagnetic; Perfusion weighted MRI

Indexed keywords

GADOBUTROL; NONIONIC CONTRAST MEDIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VOLUME; BRAIN ISCHEMIA; CONTROLLED STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; STROKE;

ANIMALS; CEREBROVASCULAR CIRCULATION; CEREBROVASCULAR DISORDERS; CONTRAST MEDIA; DATA INTERPRETATION, STATISTICAL; DISEASE MODELS, ANIMAL; GADOLINIUM; MALE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR;

EID: 0031401553     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.1880070625     Document Type: Article

References (35)

1. Villringer A, Rosen BR, Belliveau JW, et al. Dynamic imaging with lanthanide chelates In normal rat brain: contrast due to magnetic susceptibility effects. Magn Reson Med 1988; 6:164-174.
2. Rosen BR. Belliveau JW, Vevea JM, Brady TJ. Perfusion imaging with NMR contrast agents. Magn Reson Med 1990; 14: 249-265.
3. Albert MS, Huang W, Lee JH, Patlak CS, Springer JS. Susceptibility changes following bolus injections. Magn Reson Med 1993; 29:700-708.
4. Chenevert TL, Pipe JG, Williams DM, Brunberg JA. Quantitative measurement of tissue perfusion and diffusion in vivo. Magn Reson Med 1991; 17:197-212.
5. Gore JC, Majumdar S. Measurement of tissue blood flow using intravascular NMR contrast agents. Magn Reson Med 1990; 14:242-248.
6. Runge VM, Kirsch JE, Wells JW, Woolfolk CE. Assessment of cerebral perfusion by first-pass, dynamic, contrast-enhanced, steady-state free precession MR imaging: an animal study. AJR Am J Roentgenol 1993; 160:593-600.
7. de Crespigny AJ, Tsuura M, Moseley ME, Kucharczyk J. Perfusion and diffusion MR-imaging of thromboembolic stroke. J Magn Reson Imaging 1993; 3:746-754.
8. Kucharczyk J, Vexler ZS, Roberts TP, et al. Echo-planar perfusion-sensitive MR-imaging of acute cerebral ischemia. Radiology 1993; 188:711-717.
9. Kucharczyk J, Mintorovitch J, Asgari HS, Moseley ME. Diffusion/perfusion MR imaging of acute cerebral ischemia. Magn Reson Med 1991; 69:1719-1725.
10. Moseley ME, Kucharczyk J, Mintorovitch J, et al. Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR-imaging in cats. AJNR Am J Neuroradiol 1990; 11:423-429.
11. Moseley ME, Cohen Y, Mintorovitch J, et al. Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 1990; 14: 330-346.
12. Mintorovitch J, Moseley ME, Chileuitt L, Shimizu H, Cohen Y, Weinstein PR. Comparison of diffusion- and T2-weighted MRI for the early detection of cerebral Ischemia and reperfusion in rats. Magn Reson Med 1991; 18:39-50.
13. Aronen HJ, Boxerman JL, Goldberg IE, et al. Susceptibility-contrast CBV imaging: optimization of contrast dose and imaging sequences. In: Book of abstracts: Society of Magnetic Resonance in Medicine 1992. Berlin: Society of Magnetic Resonance in Medicine, 1992; 1:1129.
14. Edelman RR, Mattle HP, Atkinson DJ, et al. Cerebral blood flow: assessment with dynamic contrast-enhanced T2-weighted MR imaging at 1.5 T. Radiology 1990; 176:211-220.
15. Claussen CD, Banzer D, Pfretzschner C, KalenderWA, Schörner W. Bolus geometry and dynamics after intravenous contrast medium injection. Radiology 1984; 153:365-368.
16. Longa ZE, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989; 20:84-91.
17. Bose B, Osterholm JL, Berry R. A reproducible experimental model of focal cerebral ischemia in the cat. Brain Res 1984; 311: 385-391.
18. Levin JM, Kaufman MJ, Ross MH, et al. Sequential dynamic susceptibility contrast MR experiments in human brain: residual contrast agent effect, steady state, and hemodynamic perturbation. In: Book of abstracts: Society of Magnetic Resonance 1995. Nice: Society of Magnetic Resonance, 1995; 127.
19. Fisel CR, Ackerman JL, Buxton RB, et al. MR contrast due to microscopically heterogeneous magnetic susceptibility: numerical simulations and applications to cerebral physiology. Magn Reson Med 1991; 17:336-347.
20. Zierler KL. Theoretical basis of indicator-dilution methods for measuring flow and volume. Circ Res 1962; 10:393-407.
21. Axel L. Cerebral blood flow determination by rapid-sequence computed tomography. Radiology 1980; 137:679-686.
22. Rosen BR, Belliveau JW, Chien D. Perfusion imaging by nuclear magnetic resonance. Magn Reson Q 1989; 5:263-281.
23. Reith W. Forsting M, Vogler H, Heiland S, Sartor K. Early MR detection of experimentally induced cerebral ischemia using magnetic susceptibility contrast agents: comparison between Gadolinium DTPA and iron oxide particles. AJNR Am J Neuroradiol 1995; 16:53-60.
24. Moonen CTW, Liu G, van Gelderen P, Sobering G. A fast gradient-recalled MRI technique with increased sensitivity to dynamic susceptibility effects. Magn Reson Med 1992; 26:184-189.
25. Kucharczyk J, Asgari H, Mintorovitch J, et al. Cerebrovascular transit characteristics of DyDTPA-BMA and GdDTPA-BMA on normal and ischemic cat brain. AJNR Am J Neuroradiol 1993; 14:289-296.
26. Lauffer RB. Mechanisms of magnetic resonance contrast enhancement by relaxivity and magnetic susceptibility agents. Invest Radiol 1990; 25(suppl):32.
27. Weiskoff RM, Kühne S. MRI susceptometry: image based measurement of absolute susceptibility of MR contrast agents and human blood. Magn Reson Med 1992; 24:375-383.
28. Josephson L, Bigler J, White D. The magnetic properties of some materials affecting MR-images. Magn Reson Med 1991; 22:204-208.
29. Jones RA, Haraldseth O, Müller TB, Rinck PA, Oksendal AN. K-space substitution: a novel dynamic imaging technique. Magn Reson Med 1993; 29:830-834.
30. Pike GB, Frederickson JO, Glover GH, Enzmann DR. Dynamic susceptibility contrast imaging using a gradient-echo sequence. In: Book of abstracts: Society of Magnetic Resonance in Medicine. Berlin: Society of Magnetic Resonance in Medicine, 1992; 1:1131.
31. Gückel F, Wentz KU, Brix G, et al. MR-tomographische Untersuchungen zur zerebralen Durchblutung: Methodische Grundlagen und erste klinische Erfahrungen mit T2-gewichteten Gradientenecho-Sequenzen und KM-Gabe im Bolus. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 1992; 156: 212-217.
32. Aronen HJ, Gazit IE, Louis DN, et al. Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology 1994; 191:41-51.
33. Mühler A, Weinmann HJ. Arterial concentrations following intravenous bolus injection of gadobutrol. Comparison of 0.5 and 1.0 molar stock solutions. In: Book of abstracts: Society of Magnetic Resonance. Nice: Society of Magnetic Resonance, 1995; 1128.
34. Heiland S, Benner T, Reith W, Forsting M, Sartor K. Does higher contrast agent dosage and concentration enhance the reliability of perfusion-weighted MRI? A computer simulation. In: Book of abstracts: International Society for Magnetic Resonance in Medicine. Vancouver: International Society for Magnetic Resonance in Medicine. 1997; 1782.
35. Gmelin E, Friedrich HJ. Bolusgeometrie bei unterschiedlicher zentraler und peripherer Kontrastmittelapplikation: Studie mittels Serio-CT unter Verwendung eines nichtionischen Kontrastmittels. Röntgenblatter 1985; 38:219-223.