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Volumn 44, Issue 5, 1997, Pages 299-304

Prognostic factors in astrocytomas: Relationship of p53, MDM-2, BCL-2 and PCNA immunohistochemical expression to tumor grade and overall patient survival

Author keywords

Astrocytoma; BCL 2; MDM 2; p53; Proliferative activity; Survival

Indexed keywords

CYCLINE; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53;

EID: 0031398767     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (37)
  • 2
    • 0027993895 scopus 로고
    • Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity
    • BHARGAVA, V., KELL, D.L., VAN DE RUN, M.: Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity. Am. J. Pathol., 145, 1994, 535-540.
    • (1994) Am. J. Pathol. , vol.145 , pp. 535-540
    • Bhargava, V.1    Kell, D.L.2    Van De Run, M.3
  • 6
    • 0027773015 scopus 로고
    • Detection of the apoptosis suppressing oncoprotein Bcl-2 in hormone refractory human prostate cancers
    • COLOMBEL, M., SYMMANS, F., GIL , S.: Detection of the apoptosis suppressing oncoprotein Bcl-2 in hormone refractory human prostate cancers. Am. J. Pathol., 143, 1993, 390-400.
    • (1993) Am. J. Pathol. , vol.143 , pp. 390-400
    • Colombel, M.1    Symmans, F.2    Gil, S.3
  • 7
    • 0023700236 scopus 로고
    • Grading of astrocytomas. A simple and reproducible method
    • DAUMAS-DUPORT, C., SCHEITHAUER, B., O'FALLON, J.: Grading of astrocytomas. A simple and reproducible method. Cancer, 62, 1988, 2152-2165.
    • (1988) Cancer , vol.62 , pp. 2152-2165
    • Daumas-Duport, C.1    Scheithauer, B.2    O'Fallon, J.3
  • 9
    • 0029347661 scopus 로고
    • Expression of p53 in glioblastoma multiforme cells: Relationship to survival, proliferation and glycosylation
    • EHRMANN, J. JR., KOLÁŘ, Z., KALA, M., VOJTĚŠEK, B., KOMENDA, S.: Expression of p53 in glioblastoma multiforme cells: Relationship to survival, proliferation and glycosylation. Čs. Patol., 31, 1995, 87-91.
    • (1995) Čs. Patol. , vol.31 , pp. 87-91
    • Ehrmann Jr., J.1    Kolář, Z.2    Kala, M.3    Vojtěšek, B.4    Komenda, S.5
  • 11
    • 0028656466 scopus 로고
    • The protooncogene CHOP/GADD 153 involved in growth arrest and DNA damage response is amplified in a subset of human sarcomas
    • FORUS, A., FLORENCES, V.A., MAELANDSMO, G.M., FORSTAD, O., MYKLEBOST, O.: The protooncogene CHOP/GADD 153 involved in growth arrest and DNA damage response is amplified in a subset of human sarcomas. Cancer Genet, Cytogenet., 78, 1994, 165-171.
    • (1994) Cancer Genet, Cytogenet. , vol.78 , pp. 165-171
    • Forus, A.1    Florences, V.A.2    Maelandsmo, G.M.3    Forstad, O.4    Myklebost, O.5
  • 13
    • 0028229125 scopus 로고
    • Molecular controls of apoptosis: Differentiation/growth arrest primary response genes, protooncogenes, and tumor suppressor genes as positive and negative modulators
    • HOFFMAN , B., LIEBERMANN, D.A.: Molecular controls of apoptosis: Differentiation/growth arrest primary response genes, protooncogenes, and tumor suppressor genes as positive and negative modulators. Oncogene, 9, 1994, 1807-1812.
    • (1994) Oncogene , vol.9 , pp. 1807-1812
    • Hoffman, B.1    Liebermann, D.A.2
  • 14
    • 0027944957 scopus 로고
    • Bcl-2 protein expression and long term survival in breast cancer
    • JOENSUU, H., PYLKKANEN, L., TOIKKANEN, S.: Bcl-2 protein expression and long term survival in breast cancer. Am. J. Pathol., 145, 1994, 1191-1198.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1191-1198
    • Joensuu, H.1    Pylkkanen, L.2    Toikkanen, S.3
  • 16
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • KORSMEYER, S.J.: Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood, 80, 1992, 879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 17
    • 0027956645 scopus 로고
    • Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes
    • KRAJEWSKI, S., BODRUG, S., GASCOYNE, R., BEREAN, K., KRAJEWSKA, M., REED, J.C.: Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes. Am. J. Pathol., 145, 1994, 515-525.
    • (1994) Am. J. Pathol. , vol.145 , pp. 515-525
    • Krajewski, S.1    Bodrug, S.2    Gascoyne, R.3    Berean, K.4    Krajewska, M.5    Reed, J.C.6
  • 18
    • 7144258739 scopus 로고
    • p53 alterations and clinical outcome in low grade astrocytomas
    • KRAUS, J.A., BOLLN, C., WOLF, H.K., SCHLEGEL, U.: p53 alterations and clinical outcome in low grade astrocytomas. Clin. Neuropathol., 12, 1993, 254-259.
    • (1993) Clin. Neuropathol. , vol.12 , pp. 254-259
    • Kraus, J.A.1    Bolln, C.2    Wolf, H.K.3    Schlegel, U.4
  • 19
    • 0029621163 scopus 로고
    • Expression of Bcl-2 in reactive and neoplastic astrocytes : Lack of correlation with presence or degree of malignancy
    • KRISHNA, M., SMITH, T.W., RECHT, L.D.: Expression of Bcl-2 in reactive and neoplastic astrocytes : Lack of correlation with presence or degree of malignancy. J. Neurosurg., 83, 1995, 1017-1022.
    • (1995) J. Neurosurg. , vol.83 , pp. 1017-1022
    • Krishna, M.1    Smith, T.W.2    Recht, L.D.3
  • 20
    • 0028107586 scopus 로고
    • High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic low grade and anaplastic astrocytomas
    • LANG, F.F., MILLER, D.C., PISHARODY, S., KOSLOW, M., NEWCOMB, E.W.: High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic low grade and anaplastic astrocytomas. Oncogene, 9, 1994, 949-954.
    • (1994) Oncogene , vol.9 , pp. 949-954
    • Lang, F.F.1    Miller, D.C.2    Pisharody, S.3    Koslow, M.4    Newcomb, E.W.5
  • 22
    • 0027397760 scopus 로고
    • Bcl-2 protooncogene expression in Epstein Barr virus associated nasopharyngeal carcinoma
    • LU, Q.L., ELIA, E., LUCAS, S.: Bcl-2 protooncogene expression in Epstein Barr virus associated nasopharyngeal carcinoma. Int. J. Cancer, 53, 1993, 29-35.
    • (1993) Int. J. Cancer , vol.53 , pp. 29-35
    • Lu, Q.L.1    Elia, E.2    Lucas, S.3
  • 23
    • 0027763413 scopus 로고
    • Cell division versus cell death : A functional model of multistep neoplasia
    • MCDONNEL, T.J.: Cell division versus cell death : A functional model of multistep neoplasia. Mol. Carcinogenesis, 8, 1993, 209-213.
    • (1993) Mol. Carcinogenesis , vol.8 , pp. 209-213
    • Mcdonnel, T.J.1
  • 24
    • 0024521441 scopus 로고
    • Bcl-2 immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
    • MCDONNEL, T.J., DEANE, V., PLATT, F.: Bcl-2 immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell, 57, 1989, 78-88.
    • (1989) Cell , vol.57 , pp. 78-88
    • Mcdonnel, T.J.1    Deane, V.2    Platt, F.3
  • 26
    • 0028767635 scopus 로고
    • MDM-2 and p53: A question of balance
    • MELTZER, P.S.: MDM-2 and p53: A question of balance. J. Natl. Canc. Inst., 86, 1994, 1265-1266.
    • (1994) J. Natl. Canc. Inst. , vol.86 , pp. 1265-1266
    • Meltzer, P.S.1
  • 27
    • 0028130178 scopus 로고
    • p53 and Mdm-2 are expressed independently during cellular proliferation
    • MOSNER, J., DEPPERT, W.: p53 and Mdm-2 are expressed independently during cellular proliferation. Oncogene, 9, 1994, 3321-3328.
    • (1994) Oncogene , vol.9 , pp. 3321-3328
    • Mosner, J.1    Deppert, W.2
  • 28
    • 0026740449 scopus 로고
    • Amplification of a gene encoding a p53 associated protein in human sarcomas
    • OLINER, J.D., KINSLER, K.W., MELTZER, P.S., GEORGE, D.L., VOGELSTEIN, B.: Amplification of a gene encoding a p53 associated protein in human sarcomas. Nature, 358, 1992, 80-83.
    • (1992) Nature , vol.358 , pp. 80-83
    • Oliner, J.D.1    Kinsler, K.W.2    Meltzer, P.S.3    George, D.L.4    Vogelstein, B.5
  • 29
    • 0027179604 scopus 로고
    • Identification and characterization of multiple Mdm-2 proteins and Mdm-2/p53 protein complexes
    • OLSON, D.C., MARECHAL, V., MOMAD, J., CHEN, J., ROMOCKI, C., LEVINE, A.J.: Identification and characterization of multiple Mdm-2 proteins and Mdm-2/p53 protein complexes. Oncogene, 8, 1993, 2353-2360.
    • (1993) Oncogene , vol.8 , pp. 2353-2360
    • Olson, D.C.1    Marechal, V.2    Momad, J.3    Chen, J.4    Romocki, C.5    Levine, A.J.6
  • 30
    • 0027964904 scopus 로고
    • Immunohistochemical analysis od the interaction of p53 and Mdm-2: Fine mapping of the Mdm-2 binding site on p53 using synthetic peptide
    • PICKSLEY, S.M., VOJTĚŠEK, B., SPARKS, A., LANE, D.P.: Immunohistochemical analysis od the interaction of p53 and Mdm-2: Fine mapping of the Mdm-2 binding site on p53 using synthetic peptide. Oncogene, 9, 1994, 2523-2529.
    • (1994) Oncogene , vol.9 , pp. 2523-2529
    • Picksley, S.M.1    Vojtěšek, B.2    Sparks, A.3    Lane, D.P.4
  • 31
  • 33
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromozomal region 12q1314 in human malignant gliomas preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS and MDM-2
    • REIFENBERGER, G., REIFENBERGER, J., ICHIMURA, K., MELTZER, P.S., COLLINS, V.P.: Amplification of multiple genes from chromozomal region 12q1314 in human malignant gliomas preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS and MDM-2.Cancer Res., 54, 1994, 649-652.
    • (1994) Cancer Res. , vol.54 , pp. 649-652
    • Reifenberger, G.1    Reifenberger, J.2    Ichimura, K.3    Meltzer, P.S.4    Collins, V.P.5
  • 36
    • 0022546957 scopus 로고
    • Analysis of the structure, transcripts and protein products of bcl-2, gene involved in human follicular lymphoma
    • USA
    • TSUJIMOTO, Y., CROCE, C.M.: Analysis of the structure, transcripts and protein products of bcl-2, gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci., USA, 83, 1986, 5214-5218.
    • (1986) Proc. Natl. Acad. Sci. , vol.83 , pp. 5214-5218
    • Tsujimoto, Y.1    Croce, C.M.2
  • 37
    • 0027244853 scopus 로고
    • The p53/Mdm-2 autoregulatory feedback loop
    • WU, X., BAYLE, J.H., OLSON, D.C., LEVINE, A.J.: The p53/Mdm-2 autoregulatory feedback loop. Genes Dev., 7, 1993, 1126-1132.
    • (1993) Genes Dev. , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.C.3    Levine, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.