Brain and peripheral anandamide amidohydrolase and its inhibition by synthetic arachidonate analogues

Advances in Experimental Medicine and Biology

Volumn 433, Issue , 1997, Pages 259-264

  Di Marzo, Vincenzo ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANANDAMIDE; ARACHIDONIC ACID; HYDROLASE;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0031391217     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (16)

1. Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A and Mechoulam R, Isolation and structure of a brain costituent that binds to the cannabinoid receptor, Science 258:1946 (1992).
2. Di Marzo V, De Petrocellis L, Bisogno T and Maurelli S, Pharmacology and physiology of the endogenous cannabimimetic mediator anandamide, J Drug Dev Clin Pract 7:199 (1995).
3. Di Marzo V, Fontana A, Cadas H, Schinelli S, Cimino G, Schwartz JC and Piomelli D, Formation and inactivation of endogenous cannabinoid anandamide in central neurons, Nature 372:686 (1994).
4. Desarnaud F, Cadas H and Piomelli D, Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization, J Biol Chem 270:6030 (1995).
5. Hillard CJ, Wilkison DM, Edgemond WS and Campbell WB, Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain, Biochim Biophys Acta 1257:249 (1995).
6. Ueda N, Kurahashi Y, Yamamoto S and Tokunaga T, Partial purification and characterization of the porcine brain enzyme hydrolizing and synthesizing anandamide, J Biol Chem 270:23823 (1995).
7. Facci L, Dal Toso R, Romanello S, Buriani A, Skaper SD and Leon A, Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide, Proc Natl Acad Sci USA 92:3376 (1995).
8. Maurelli S, Bisogno T, De Petrocellis L, Di Luccia A, Marino G and Di Marzo V, Two novel class of neuroactive fatty acid amides are substates for mouse neuroblastoma anandamide amidohydrolase, FEBS Lett 377:82 (1995).
9. Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL and Lerner RA, Chemical characterization of a family of brain-lipids that induce sleep, Science 268:1506 (1995).
10. Cravatt BF, Giang DK, Mayfield SP, Boger DL, Lerner RA and Gilula NB, Molecular characterization of an enzyme that degrades neuromodulatory fatty acid amides, Nature 384:83 (1996).
11. Bisogno T, Ventriglia M, Mosca M, Milone A, Cimino G and Di Marzo V, Occurrence and metabolism of anandamide and related acylethanolamides in ovaries of the sea urchin Paracentrotus lividus, Biochim Biophys Acta (1997) in press.
12. De Petrocellis L, Melck D, Ueda N, Maurelli S, Kurahashi Y, Yamamoto S, Marino G and Di Marzo V, Novel inhibitors of brain, neuronal and basophilic anandamide aminohydrolase, Biochem Biophys Res Comm 231:82 (1997).
13. Balsinde J and Dennis EA, Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages, J Biol Chem 271:6758 (1996).
14. Koutek B, Prestwich GD, Howlett AC, Chin SA, Salehani D, Akhavan N and Deutsch DG, Inhibitors of arachidonyl ethanolamide hydrolisis, J Biol Chem 269:22937 (1994).
15. Alanko J, Kurahashi Y, Yoshimoto T, Yamamoto S and Baba K, Panaxynol, a polyacetylene compound isolated from oriental medicine, inhibits mammalian lipoxygenases, Biochem Pharmacol 48:1979 (1994).
16. Patterson JE, Ollmann IR, Cravatt BF, Boger DL, Wong C-H and Lerner RA, Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cir-9-octadecenoamide, J Am Chem Soc 118:5938 (1996).