Functional activity of the CFTR Cl- channel in human myocardium

Heart and Vessels

Volumn 12, Issue 6, 1997, Pages 255-261

  Yajima, Toshitaka ^a   Nagashima, Hirotaka ^a   Tsutsumi Sakai, Rieko ^a   Hagiwara, Nobuhisa ^a   Hosoda, Saichi ^a   Quertermous, Thomas ^b   Kasanuki, Hiroshi ^a   Kawana, Masatoshi ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP dependent chloride channel; Cystic fibrosis transmembrane conductance regulator (CFTR); Human atrial myocyte; Rabbit ventricular myocyte; Reverse transcriptase polymerase chain reaction (RT PCR); Whole cell voltage clamp

Indexed keywords

CHLORIDE CHANNEL; CYCLIC AMP; MESSENGER RNA; RNA DIRECTED DNA POLYMERASE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADOLESCENT; ADULT; ANIMAL TISSUE; ARTICLE; CHILD; COLON MUCOSA; CONDUCTANCE; CYSTIC FIBROSIS; GENE AMPLIFICATION; HEART ATRIUM; HEART MUSCLE; HEART VENTRICLE; HUMAN; HUMAN TISSUE; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RABBIT; RNA SPLICING;

EID: 0031375084     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02766800     Document Type: Article

References (23)

1. Bahinski A, Nairn AC, Greengard P, Gadsby DC (1989) Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes. Nature 340:718-721
2. Harvey RD, Hume JR (1989) Autonomic regulation of a chloride current in heart. Science 244:983-985
3. Harvey RD, Hume JR (1989) Isoproterenol activates a chloride current, not the transient outward current, in rabbit ventricular myocytes. Am J Physiol 257:C1177-1181
4. - channel resembles the cystic fibrosis transmembrane conductance regulator. Nature 360:81-84
5. Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou JL (1989) Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA (published erratum appears in Science (1989) 245(4925):1437). Science 245:1066-1073
6. - channels in heart. Am J Physiol 264:H2214-2220
7. - channels in heart. Circ Res 71:1002-1007
8. Sorota S, Siegal MS, Hoffman BF (1991) The isoproterenol-induced chloride current and cardiac resting potential. J Mol Cell Cardiol 23:1191-1198
9. Takano M, Noma A (1992) Distribution of the isoprenaline-induced chloride current in rabbit heart. Pflügers Arch 420:223-226
10. James AF, Tominaga T, Okada Y, Tominaga M (1996) Distribution of cAMP-activated chloride current and CFTR mRNA in the guinea pig heart. Circ Res 79:201-207
11. Oz MC, Sorota S (1995) Forskolin stimulates swelling-induced chloride current, not cardiac cystic fibrosis transmembrane-conductance regulator current, in human cardiac myocytes. Circ Res 76:1063-1070
12. Sakai R, Hagiwara N, Kasanuki H, Hosoda S (1995) Chloride conductance in human atrial cells. J Mol Cell Cardiol 27:2403-2408
13. Berul CI, Sweeten T, Vetter VL, Morad M (1997) Lack of cystic fibrosis transmembrane regulator-type chloride current in pediatric human atrial myocytes. Life Sci 60:189-197
14. Escande D, Coulombe A, Faivre JF, Deroubaix E, Coraboeuf E (1987) Two types of transient outward currents in adult human atrial cells. Am J Physiol 252:H142-H148
15. Powell T, Twist VW (1976) A rapid technique for the isolation and purification of adult cardiac muscle cells having respiratory control and a tolerance to calcium. Biochem Biophys Res Commun 72:327-333
16. Hagiwara N, Masuda H, Shoda M, Irisawa H (1992) Stretch-activated anion currents of rabbit cardiac myocytes. J Physiol (Lond) 456:285-302
17. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100
18. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem 162:156-159
19. - channels in heart. Jpn J Physiol 44 Suppl 2:S177-S182
20. Warth JD, Collier ML, Hart P, Geary Y, Gelband CH, Chapman T, Horowitz B, Hume JR (1996) CFTR chloride channels in human and simian heart. Cardiovasc Res 31:615-624
21. Veres G, Gibbs RA, Scherer SE, Caskey CT (1987) The molecular basis of the sparsed fur mouse mutation. Science 237:415-417
22. Noonan KE, Roninson IB (1988) mRNA phenotyping by enzymatic amplification of randomly primed cDNA. Nucleic Acids Res 16:10366
23. Hart P, Warth JD, Levesque PC, Collier ML, Geary Y, Horowitz B, Hume JR (1996) Cystic fibrosis gene encodes a cAMP-dependent chloride channel in heart. Proc Natl Acad Sci USA 93:6343-6348