Hydroxynimesulide, the main metabolite of nimesulide, prevents hydroperoxide/hemoglobin-induced hemolysis of rat erythrocytes

Drugs under Experimental and Clinical Research

Volumn 23, Issue 5-6, 1997, Pages 157-165

  Maffei Facino, R ^a   Carini, M ^a   Aldini, G ^a   Calloni, M T ^a  

^a Istituto Chimico Farmaceutico   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CUMENE HYDROPEROXIDE; DRUG METABOLITE; HEMOGLOBIN; HYDROXYNIMESULIDE; MEMBRANE LIPID; MEMBRANE PROTEIN; NIMESULIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ERYTHROCYTE MEMBRANE; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; TURBIDIMETRY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZENE DERIVATIVES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; HEMOGLOBINS; HEMOLYSIS; MALE; MEMBRANE PROTEINS; OXIDATION-REDUCTION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SULFONAMIDES;

EID: 0031373867     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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