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Volumn 3, Issue 3, 1997, Pages 207-210

Iodination of benzocyclic amines with mercury(II) oxide-iodine reagent

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EID: 0031316589     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.1997.3.3.207     Document Type: Article
Times cited : (5)

References (41)
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    • A. P. Terentyev, L. I. Belenky and L. A. Yanavskaya, Zh. Obshch. Khim. 24, 1265 (1954); Chem. Abstr. 49, 12327 (1953)
    • (1953) Chem. Abstr. , vol.49 , pp. 12327
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    • M. N. Preobrazhenska, M. V. Fedotova, N. P. Sorokina, O. B. Ogareva, N. V. Uvarova and N. N. Suvorov, Zh. Obschch. Khim. 34, 1310 (1964); Chem. Abstr. 61, 1822h (1964)
    • (1964) Chem. Abstr. , vol.61
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    • H. A. Muathan, J. Chem. Research (S) 404 (1994); (M) 2201 (1994)
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  • 33
    • 2742550402 scopus 로고    scopus 로고
    • note
    • 2 at room temperature provided N,N-diethyl-4-iodoaniline (92%), exclusively. A similar treatment afforded 4-iodoaniline (0.5/1, 15min, 68%), 4-iodo-N-methylaniline (1/1, 1h, 75%) and 4-iodoacetanilide (3/3, 17h, 72%).
  • 34
    • 2742532856 scopus 로고    scopus 로고
    • note
    • The solution may be washed with a hypo solution to remove excess iodine.
  • 37
    • 0001307168 scopus 로고
    • Interestingly, under these conditions benzofuran was recovered unchanged, and benzo[b]thiophene was converted to its 3-iodo derivative. See: R. Gaertner, J. Am. Chem. Soc. 74, 4950 (1952)
    • (1952) J. Am. Chem. Soc. , vol.74 , pp. 4950
    • Gaertner, R.1
  • 40
    • 2742526270 scopus 로고    scopus 로고
    • note
    • Six- and seven-membered benzocyclic amides, such as N-acetyl-1,2,3,4-tetrahydroquinoline and 2,3,4,5-tetrahydro-1H/-benzazepin-2-one, were found to be unreactive.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.