Genotoxin resistance properties of transgenic tobacco plants expressing bacteriophage T4 DenV and Saccharomyces cerevisiae Apn1 proteins

Biochemistry and Cell Biology

Volumn 75, Issue 4, 1997, Pages 435-443

  Lapointe, Gilles ^a,b   Winchcombe Forhan, Charlene ^a   Evans, David H ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b LAURENTIAN FORESTRY CENTRE   (Canada)

Author keywords

Alkylating agents; Apn1; DenV; Tobacco plants; UV light

Indexed keywords

ALKYLATING AGENT; APN1 PROTEIN, S CEREVISIAE; DEOXYRIBONUCLEASE; GLYCOSIDASE; MULTIENZYME COMPLEX; MUTAGENIC AGENT; OXIDIZING AGENT; SACCHAROMYCES CEREVISIAE PROTEIN; UV ENDONUCLEASE;

ARTICLE; BACTERIOPHAGE T4; BIOSYNTHESIS; DNA REPAIR; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFORMATION; GENETICS; PLANT; RADIATION EXPOSURE; SACCHAROMYCES CEREVISIAE; TOBACCO; TRANSGENIC PLANT; ULTRAVIOLET RADIATION;

ALKYLATING AGENTS; BACTERIOPHAGE T4; DNA REPAIR; ENDODEOXYRIBONUCLEASES; MULTIENZYME COMPLEXES; MUTAGENS; N-GLYCOSYL HYDROLASES; OXIDANTS; PLANTS, GENETICALLY MODIFIED; PLANTS, TOXIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TOBACCO; TRANSFORMATION, GENETIC; ULTRAVIOLET RAYS;

EID: 0031308709     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o97-057     Document Type: Article

References (23)

1. Allen, R.D. 1995. Dissection of oxidative stress tolerance using transgenic plants. Plant Physiol. 107: 1049-1054.
2. Angelis, K., Briza, J., Satava, J., Skakal, I., Veleminsky, J., Vlasak, J., Kleibl, K., and Margison, G.P. 1992. Increased resistance to the toxic effects of alkylating agents in tobacco expressing the E. coli DNA repair gene ada. Mutat. Res. 273: 271-280.
3. Babiychuk, E., Kushnir, S., van Montagu, M., and Inze, D. 1994. The Arabidopsis thaliana apurinic endonuclease Arp reduces human transcription factors Fos and Jun. Proc. Natl. Acad. Sci. U.S.A. 91: 3299-3303.
4. Barber, J., and Anderson, B. 1992. Too much of a good thing: light can be bad for photosynthesis. Trends Biochem. Sci. 17: 61-66.
5. Barzilay, G., and Hickson, I.D. 1995. Structure and function of AP endonucleases. BioEssays, 17: 713-719.
6. Batschauer, A. 1993. A plant gene for photolyase: an enzyme catalyzing the repair of UV-light-induced DNA damage. Plant J. 4: 705-709.
7. Blaisdell, P., and Warner, H. 1983. Partial purification and characterization of a uracil-DNA glycosylase from wheat germ. J. Biol. Chem. 258: 1603-1609.
8. Britt, A.B., Chen, J.J., Wykoff, D., and Mitchell, D. 1993. A UV-sensitive mutant of Arabidopsis defective in the repair of pyrimidine-pyrimidinone (6-4) dimers. Science (Washington, D.C.), 261: 1571-1574.
9. Davies, C., Howard, D., Tam, G., and Wong, N. 1994. Isolation of Arabidopsis thaliana mutants hypersensitive to gamma radiation. Mol. Gen. Genet. 243: 660-665.
10. Demple, B., and Harrison, L. 1994. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 63: 915-948.
11. Evans, D.H., and Linn, S. 1984. Excision repair of pyrimidine dimers from simian virus 40 minichromosomes in vitro. J. Biol. Chem. 259: 10 252 - 10 259.
12. Evans, D.H., Bugeja, F.X., Yacyshyn, B.J., and Morgan, A.R. 1984. Rapid sensitive fluorescence assays for DNA endonucleases and DNA glycosylases. Can. J. Biochem. Cell Biol. 62: 1275-1282.
13. Friedberg, E.C., Walker, G.C., and Siede, W. 1995. Base excision repair. In DNA repair and mutagenesis. ASM Press, Washington, D.C. pp. 135-190.
14. Hamilton, K.K., Kim, P.M.H., and Doetsch, P.W. 1992. A eukaryotic DNA glycosylase/lyase recognizing ultraviolet light-induced pyrimidine dimers. Nature (London), 356: 725-728.
15. Harlow, G.R., Jenkins, M.E., Pittalwala, T.S., and Mount, D.W. 1994. Isolation of uvh1, an Arabidopsis mutant hypersensitive to ultraviolet light and ionizing radiation. Plant Cell, 6: 227-235.
16. Horsch, R.B., Fry, J.E., Hoffmann, N.L., Eichholtz, D., Rogers S.G., and Fraley, R.T. 1985. A simple and general method for transferring genes into plants. Science (Washington, D.C.), 227: 1229-1231.
17. Kim, J., and Linn, S. 1988. The mechanisms of action of E. coli endonuclease III and T4 UV endonuclease V at AP sites. Nucleic Acids Res. 16: 1135-1141.
18. Lapointe, G., Mori, T., and Evans, D.H. 1996. Tobacco plants expressing T4 endonuclease V show enhanced sensitivity to ultraviolet light and DNA alkylating agents. Mutat. Res. 351: 19-31.
19. McLennan, A.G. 1987. The repair of ultraviolet light-induced DNA damage in plant cells. Mutat. Res. 181: 1-7.
20. McMillan, S., Edenberg, HJ., Radany, E.H., Friedberg, R.C., and Friedberg, E.C. 1981. denV gene of bacteriophage T4 codes for both pyrimidine dimer-DNA glycosylase and apyrimidinie endonuclease activities. J. Virol. 40: 211-223.
21. Popoff, S.C., Spira, A.I., Johnson, A.W., and Demple, B. 1990. Yeast structural gene APN1 for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc. Natl. Acad. Sci. U.S.A. 87: 4193-4197.
22. Porra, R.J., Thompson, W.A., and Kriedemann, P.E. 1989. Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy. Biochim. Biophys. Acta, 975: 384-394.
23. Prasad, T.K., Anderson, M.D., Martin, B.A., and Stewart, C.R. 1994. Evidence for chilling-induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide. Plant Cell, 6: 65-74.