Amlodipine inhibits rat microsomal cytochrome P450-mediated drug biotransformation

Journal of Pharmaceutical Sciences

Volumn 86, Issue 12, 1997, Pages 1501-1503

  Drobitch, Robert K ^a,c   Mclellan, Roman A ^b   Renton, Kenneth W ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b WAYNE STATE UNIVERSITY   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; CALCIUM CHANNEL BLOCKING AGENT; CYTOCHROME P450; ISOENZYME; ERYTHROMYCIN N DEMETHYLASE; ETHOXYRESORUFIN DEETHYLASE; LAURIC ACID; NITROPHENOL HYDROXYLASE; PHENOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOTRANSFORMATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LIVER MICROSOME; MALE; RAT; SPRAGUE DAWLEY RAT; ANIMAL CELL; ANIMAL TISSUE; CALCIUM ANTAGONISM; DRUG MECHANISM; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME INHIBITION; INHIBITION KINETICS; NONHUMAN;

AMLODIPINE; ANIMALS; BIOTRANSFORMATION; CALCIUM CHANNEL BLOCKERS; CYTOCHROME P-450 ENZYME SYSTEM; ISOENZYMES; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031307104     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970188t     Document Type: Article

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