Transcriptional Regulation of the Complement Receptor 2 Gene: Role of a Heterogeneous Nuclear Ribonucleoprotein

Journal of Immunology

Volumn 159, Issue 11, 1997, Pages 5492-5501

  Tolnay, Mate ^a   Lambris, John D ^b   Tsokos, George C ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; COMPLEMENT RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; B LYMPHOCYTE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; TIME;

AMINO ACID SEQUENCE; B-LYMPHOCYTES; BUCLADESINE; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RECEPTORS, COMPLEMENT; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0031296662     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Ahearn, J. M., and D. T. Fearon. 1989. Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21). Adv. Immunol. 46:183.
2. Tsoukas, C. D., and J. D. Lambris. 1993. Expression of EBV/C3d receptors on T cells: biological significance. Immunol. Today 14:56.
3. Tedder, T. F., L. T. Clement, and M. D. Cooper. 1984. Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody. J. Immunol. 133:678.
4. Luxembourg, A. T., and N. R. Cooper. 1994. Modulation of signaling via the B cell antigen receptor by CD21, the receptor for C3dg and EBV. J. Immunol. 153:4448.
5. Tsokos, G. C., J. D. Lambris, F. D. Finkelman, E. D. Anastassiou, and C. H. June. 1990. Monovalent ligands of complement receptor 2 inhibit whereas polyvalent ligands enhance anti-Ig-induced human B cell intracytoplasmic free calcium concentration. J. Immunol. 144:1640.
6. Carter, R. H., and D. T. Fearon. 1989. Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM. J. Immunol. 143:1755.
7. Kozono, Y., R. C. Duke, M. S. Schleicher, and V. M. Holers. 1995. Co-ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI-231 cells from anti-surface IgM-induced apoptosis. Eur. J. Immunol. 25:1013.
8. Bonnefoy, J. Y., S. Henchoz, D. Hardie, M. J. Holder, and J. Gordon. 1993. A subset of anti-CD21 antibodies promote the rescue of germinal center B cells from apoptosis. Eur. J. Immunol. 23:969.
9. Matsumoto, A. K., J. Kopicky-Burd, R. H. Carter, D. A. Tuveson, T. F. Tedder, and D. T. Fearon. 1991. Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19. J. Exp. Med. 173:55.
10. Bouillie, S., M. Barel, P. Drane, B. Cassinat, M. Balbo, V. M. Holers, and R. Frade. 1995. Epstein-Barr virus/C3d receptor (CR2, CD21) activated by its extracellular ligands regulates pp105 phosphorylation through two distinct pathways. Eur. J. Immunol. 25:2661.
11. Frade, R., A. Gauffre, J. Hermann, and M. Barel. 1992. EBV/C3d receptor (CR2) interacts by its intracytoplasmic carboxy-terminal domain and two distinct binding sites with the p53 anti-oncoprotein and the p68 calcium-binding protein. J. Immunol. 149:3232.
12. Boyd, A. W., K. C. Anderson, A. S. Freedman, D. C. Fisher, B. Slaughenhoupt, S. F. Schlossman, and L. M. Nadler. 1985. Studies of in vitro activation and differentiation of human B lymphocytes. I. Phenotypic and functional characterization of the B cell population responding to anti-Ig antibody. J. Immunol. 134: 1516.
13. Thyphronitis, G., T. Kinoshita, K. Inoue, J. E. Schweinle, G. C. Tsokos, E. S. Metcalf, F. D. Finkelman, and J. E. Balow. 1991. Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo. J. Immunol. 147:224.
14. Heyman, B., E. J. Wiersma, and T. Kinoshita. 1990. In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody. J. Exp. Med. 172:665.
15. Hebell, T., J. M. Ahearn, and D. T. Fearon. 1991. Suppression of the immune response by a soluble complement receptor of B lymphocytes. Science 254:102.
16. Ahearn, J. M., M. B. Fischer, D. Croix, S. Goerg, M. Ma, J. Xia, X. Zhou, R. G. Howard, T. L. Rothstein, and M. C. Carroll. 1996. Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity 4:251.
17. Rayhel, E. J., M. H. Dehoff, and V. M. Holers. 1991. Characterization of the human complement receptor 2 (CR2, CD21) promoter reveals sequences shared with regulatory regions of other developmentally restricted B cell proteins. J. Immunol. 146:2021.
18. Volanakis, J. E. 1995. Transcriptional regulation of complement genes. Annu. Rev. Immunol. 13:277.
19. Yang, L. M., M. Behrens, and J. J. Weis. 1991. Identification of 5′-regions affecting the expression of the human CR2 gene. J. Immunol. 147:2404.
20. Dreyfuss, G., M. J. Matunis, S. Pinol-Roma, and C. G. Burd. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:289.
21. Choi, Y. D., P. J. Grabowski, P. A. Sharp, and G. Dreyfuss. 1986. Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science 231:1534.
22. Zhang, W., B. J. Wagner, K. Ehrenman, A. W. Schaefer, C. T. DeMaria, D. Crater, K. DeHaven, L. Long, and G. Brewer. 1993. Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol. Cell. Biol. 13:7652.
23. Tomonaga, T., and D. Levens. 1995. Heterogeneous nuclear ribonucleoprotein K is a DNA-binding transactivator. J. Biol. Chem. 270:4875.
24. Tay, N., S. H. Chan, and E. C. Ren. 1992. Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II. J. Virol. 66:6841.
25. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
26. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Northern hybridization. In Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p. 7.39.
27. Marzluff, W. F., and R. C. Huang. 1975. Chromatin directed transcription of 5S and tRNA genes. Proc. Natl. Acad. Sci. USA 72:1082.
28. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octaraer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:6419.
29. Chodosh, L. A., R. W. Carthew, and P. A. Sharp. 1986. A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol. Cell. Biol. 6:4723.
30. Chodosh, L. A. 1988. UV cross-linking of proteins to nucleic acids. In Current Protocols in Molecular Biology. F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. A. Smith, J. G. Seidman, and K. Struhl, eds. John Wiley & Sons, New York, p. 12.5.1.
31. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475.
32. Beansavage, M., G. Mattson, S. Besai, J. W. Nielander, S. Morgensen, and E. J. Conklin. 1992. Biotinylated nucleic acid probes. In Avidin-Biotin Chemistry: A Handbook. Pierce Chemical Company, Rockford, IL, p. 97.
33. Hager, D. A., and R. R. Burgess. 1980. Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes. Anal. Biochem. 109:76.
34. Mavroidis, M., J. O. Sunyer, and J. D. Lambris. 1995. Isolation, primary structure, and evolution of the third component of chicken complement and evidence for a new member of the alpha 2-macroglobulin family. J. Immunol 154:2164.
35. Seiler-Tuyns, A., P. Walker, E. Martinez, A. M. Merillat, F. Givel, and W. Wahli. 1986. Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line. Nucleic Acids Res. 14:8755.
36. Segal, S. 1986. DEAE dextran-mediated transfection of nonadherent and adherent mammalian cells. In Basic Methods in Molecular Biology. L. G. Davis, M. D. Dibner, and J. F. Battey, eds. Elsevier, New York, p. 290.
37. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Assays for chloramphenicol acetyltransferase. In Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p. 16.60.
38. Nichols, M., F. Weih, W. Schmid, C. DeVack, E. Kowenz-Leutz, B. Luckow, M. Boshart, and G. Schutz. 1992. Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription. EMBO J. 11:3337.
39. Gonzalez, G. A., and M. R. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675.
40. Xie, H., T. C. Chiles, and T. L. Rothstein. 1993. Induction of CREB activity via the surface Ig receptor of B cells. J. Immunol. 151:880.
41. Brown, A. J. P. 1993. mRNA translation and turnover: a cellular perspective on their relationship. Trends Cell Biol. 3:180.
42. Carter, R. H., and D. T. Fearon. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105.
43. Sato, S., N. Ono, D. A. Steeber, and T. F. Tedder. 1996. CD19 is a response regulator of B lymphocyte development, activation and differentiation. FASEB J. 10:A1462.
44. Kajita, Y., J. Nakayama, M. Aizawa, and F. Ishikawa. 1995. The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0: common modular structure and binding properties of the 2xRBD-Gly family. J. Biol. Chem. 270:22167.
45. Ishikawa, F., M. J. Matunis, G. Dreyfuss, and T. R. Cech. 1993. Nuclear proteins that bind the pre-mRNA 3′ splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol. Cell. Biol. 13:4301.
46. Brewer, G. 1991. An A+U-rich element RNA binding factor regulates c-myc mRNA stability in vitro. Mol. Cell. Biol. 11:2460.
47. Benbrook, D. M., and N. C. Jones. 1994. Different binding specificities and transactivation of variant CRE's by CREB complexes. Nucleic Acids Res. 22:1463.