The synergistic effect of tetrandrine and rotundine on the action potential of rabbit sinus node dominant pacemaker cell and calcium currents of ventricular myocytes from guinea-pig

Yaoxue Xuebao

Volumn 32, Issue 3, 1997, Pages 161-165

  Yan, S ^a   Yao, W X ^a   Xia, G J ^a   Tong, Q S ^a   Jiang, M X ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Action potential; Calcium channel; Patch clamp; Rotundine; Tetrandrine

Indexed keywords

ALKALOID; BENZYLISOQUINOLINE DERIVATIVE; BERBERINE DERIVATIVE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; TETRAHYDROPALMATINE; TETRANDRINE;

ACTION POTENTIAL; ANIMAL; ARTICLE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; FEMALE; GUINEA PIG; HEART MUSCLE; MALE; PHYSIOLOGY; RABBIT; SINUS NODE;

ACTION POTENTIALS; ALKALOIDS; ANIMALS; BENZYLISOQUINOLINES; BERBERINE ALKALOIDS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; GUINEA PIGS; MALE; MYOCARDIUM; RABBITS; SINOATRIAL NODE;

EID: 0031290975     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Kreitner D. Electrophysiological study of the two main pacemaker mechanisms in the rabbit sinus node. Cardiovasc Res, 1985, 19: 304
2. 2+ current in isolated nerve terminals of the rat neurohypophysis. Pflugers Arch , 1992, 421:558
3. Yanagihara K, Irisawa H. Potassium current during the pacemaker depolarization in rabbit sinoatrial node cell. Pflugers Arch, 1980, 388 :255
4. Tritthart H, Volkmann R, Weiss R, et al. Calcium-mediated action potentials in mammalian myocardium. Naunyn Schmiedebergs Arch Pharmacol, 1973, 280:239