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Volumn 32, Issue 12, 1997, Pages 924-927

Distinguishing CYP2D6 homozygous and heterozygous extensive metabolizers by dextromethorphan phenotyping

Author keywords

Dextromethorphan; Heterozygote; Homozygote; Phenotyping

Indexed keywords

CYTOCHROME P450 2D6; DEXTROMETHORPHAN;

EID: 0031290940     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (8)
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  • 2
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    • Rapid screening for polymorphisms in dextromethorphan and mephenytoin metabolism
    • Guttendorf RJ, Britto M, Blouin RA, et al. Rapid screening for polymorphisms in dextromethorphan and mephenytoin metabolism. Br J Clin Pharmacol, 1990, 29:759
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  • 3
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    • The cytochrome P450-2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry
    • Chen S, Chou WH, Blouin RA, et al. The cytochrome P450-2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry. Clin Pharmacol Ther, 1996, 60:522
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 522
    • Chen, S.1    Chou, W.H.2    Blouin, R.A.3
  • 4
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D6 locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, et al. Inherited amplification of an active gene in the cytochrome P450 CYP2D6 locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA, 1993, 90: 11825
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3
  • 5
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    • Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations
    • Alvan G, Bechtel P, Iselius L, et al. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur J Clin Pharmacol, 1990, 39:533
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    • Alvan, G.1    Bechtel, P.2    Iselius, L.3
  • 6
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    • Relation between debrisoquine oxidation phenotype and morphological, biological and pathological variables in a large population
    • Vincent-Viry M, Muller J, Fournier B, et al. Relation between debrisoquine oxidation phenotype and morphological, biological and pathological variables in a large population. Clin Chem, 1991, 37:327
    • (1991) Clin Chem , vol.37 , pp. 327
    • Vincent-Viry, M.1    Muller, J.2    Fournier, B.3
  • 7
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    • Low frequency of slow debrisoquine hydroxylation in a native Chinese population
    • Lou YQ, Liu Y, Bertilsson L, et al. Low frequency of slow debrisoquine hydroxylation in a native Chinese population. Lancet, 1987, ii(8563):852
    • (1987) Lancet , vol.2 , Issue.8563 , pp. 852
    • Lou, Y.Q.1    Liu, Y.2    Bertilsson, L.3
  • 8
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    • Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylation of debrisoquine and S mephenytoin
    • Bertilsson L, Lou YQ, Du YL, et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylation of debrisoquine and S mephenytoin. Clin Pharmacol Ther, 1992, 51:388
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    • Bertilsson, L.1    Lou, Y.Q.2    Du, Y.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.