Preparation and anti-HIV activity study of baicalien and its benzylated derivatives

Yaoxue Xuebao

Volumn 32, Issue 2, 1997, Pages 140-143

  Zhao, J ^a   Zhang, Z P ^a   Chen, H S ^a   Chen, X H ^a   Zhang, X Q ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Anti HIV; Baicalein; Baicalin

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BAICALEIN; BAICALIN; FLAVANONE DERIVATIVE; FLAVONOID; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; CHEMISTRY; DRUG EFFECT; HYDROLYSIS; SYNTHESIS;

ANTI-HIV AGENTS; FLAVANONES; FLAVONOIDS; HIV-1 REVERSE TRANSCRIPTASE; HYDROLYSIS; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 0031290837     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Zhang XQ, Tang XS, Chen HS. Inhibition of HIV replication by baicalin and S. baicalensis extract in H9 cell culture. Chin Med Sci J, 1991,6:230
2. Baylor NW, Fu T, Yan YD. Inhibition of human T cell leukemia virus by the plant flavonoid baicalin. J Infect Dis, 1992,165:433
3. Li BQ, Fu T, Yan YD, et al. Inhibition of HIV infection by baicalin - a flavonoid compound purified from Chinese herbal medicine. Cell Mol Biol Res, 1993,39:119
4. Chen HS, XQ Zhang, L Tang, et al. Inhibition of baicalin on HIV-1 in vitro and on Rav Mulv in vivo. The 5th International Antiviral Symposium. Nice, France, 1994, June
5. Ono K, Nakane H, Fukushima M, et al. Inhibition of reverse transcriptase activity by a flavonoid compound, 5, 6, 7-trihydroxy flavone. Biochem Biophys Res Commun, 1989,160:982