Preliminary study on the absorption, distribution and excretion of doxophylline in rats

Yaoxue Xuebao

Volumn 32, Issue 2, 1997, Pages 81-84

  Guo, H ^a   Xu, X Y ^a   He, L Y ^a   Huang, J H ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Doxophylline; High performance thin layer chromatography; Pharmacokinetics

Indexed keywords

ANTITUSSIVE AGENT; DOXOFYLLINE; DRUG DERIVATIVE; THEOPHYLLINE;

ABSORPTION; ANIMAL; ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; RAT; THIN LAYER CHROMATOGRAPHY; TISSUE DISTRIBUTION; WISTAR RAT;

ABSORPTION; ANIMALS; ANTITUSSIVE AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; MALE; RATS; RATS, WISTAR; THEOPHYLLINE; TISSUE DISTRIBUTION;

EID: 0031290805     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Angelis LD. ABC-12/3. Drugs Future, 1982,7:301
2. Franzone JS, Reboani C, Fonzo D, et al. Pharmacological researches on 2-(7′-Theophyllinemethyl)-1, 3-dioxolane. Farmaco (Sci), 1981,36:201
3. Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn, 1988,295:221
4. Franzone JS, Cravanzola C, Masera F. Preliminary studies on the absorption, distribution and excretion of 2-(7′-theophyllinemethyl)-1, 3-dioxolane in the rat. Farmaco (Sci), 1981,36:3
5. Grosa G, Franzone JS, Biglino G. Metabolism of doxophylline by rat liver microsomes. Drug Metab Dispos, 1986, 14: 267