Improved 32P-postlabelling assay for the quantification of the major platinum-DNA adducts

Carcinogenesis

Volumn 18, Issue 9, 1997, Pages 1767-1774

  Welters, Marij J P ^a   Maliepaard, Marc ^b   Jacobs Bergmans, Angela J ^a   Baan, Robert A ^a   Schellens, Jan H M ^b   Ma, Jianguo ^c   Van Der Vijgh, Wim J F ^d   Braakhuis, Boudewijn J M ^d   Fichtinger Schepman, Anne Marie J ^a  

^a TNO   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c ERASMUS MC CANCER INSTITUTE   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DNA; PHOSPHORUS 32; PLATINUM; ANTINEOPLASTIC AGENT; CISPLATIN DNA ADDUCT; CISPLATIN-DNA ADDUCT; PHOSPHORUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER; CPG ISLAND; DNA ADDUCT; DRUG DNA INTERACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; ION EXCHANGE CHROMATOGRAPHY; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; STANDARD; THIN LAYER CHROMATOGRAPHY; TUMOR XENOGRAFT; ANIMAL; CELL CULTURE; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CISPLATIN; DNA; DNA ADDUCTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MICE; PHOSPHORUS RADIOISOTOPES; TUMOR CELLS, CULTURED;

EID: 0031284675     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.9.1767     Document Type: Article

References (26)

1. 32P-postlabelling. Nucleic Acids Res., 23, 1300-1306.
2. Fichtinger-Schepman, A.M.J., Van der Veer, J.L., Den Hartog, J.H.J., Lohman, P.H.M. and Reedijk, J. (1985) Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation. Biochemistry, 24, 707-713.
3. Fichtinger-Schepman, A.M.J., Welters, M.J.P., Van Dijk-Knijnenburg, H.C.M., Van der Sterre, M.L.T., Tilby, M.J., Berends, F. and Baan, R.A. (1996) Detection of adducts formed upon treatment of DNA with cisplatin and carboplatin. In Pinedo, H.M. and Schornagel, J.H. (ed.) Platinum and other Metal Coordination Compounds in Cancer Chemotherapy 2. Plenum Press, New York, pp. 107-119.
4. Reed, E., Sauerhoff, S. and Poirier, M.C. (1988) Quantitation of platinum-DNA binding after therapeutic levels of drug exposure. A novel use of graphite furnace spectrometry. Atom. Spectrosc., 9, 93-95.
5. Ma, J., Verweij, J., Kolker, H.J., Van Ingen, H.E., Stoter, G. and Schellens, J.H.M. (1994) Pharmacokinetic-dynamic relationship of cisplatin in vitro: simulation of an i.v. bolus and 3 h and 20 h infusion. Brit J. Cancer, 69, 858-862.
6. Tilby, M.J., Johnson, C., Knox, R.J., Cordell, J., Roberts, J.J. and Dean, C.J. (1991) Sensitive detection of DNA modifications induced by cisplatin and carboplatin in vitro and in vivo using a monoclonal antibody. Cancer Res., 51, 123-129.
7. Poirier, M.C., Lippard, S.J., Zwelling, L.A., Ushay, H.M., Kerrigan, D., Thill, C.C., Santella, R.M., Grunberger, D. and Yuspa, S.H. (1982) Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adduct formed in vivo and in vitro. Proc. Natl Acad. Sci. USA, 79, 6443-6447.
8. Reed, E., Yuspa, S.H., Zwelling, L.A., Ozols, R.F. and Poirier, M.C. (1986) Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy. J. Clin. Invest., 77, 545-550.
9. Terheggen, P.M.A.B., Floot, B.G.J., Lempers, E.L.M., Van Tellingen, O., Begg, A.C. and Den Engelse, L. (1991) Antibodies against cisplatin-modified DNA and cisplatin-modified (di)nucleotides. Cancer Chemoth. Pharm., 28, 185-191.
10. Blommaert, F.A., Michael, C., Terheggen, P.M.A.B., Muggia, F.M., Kortes, V., Schornagel, J.H., Hart, A.A.M. and Den Engelse, L. (1993) Drug-induced DNA modification in buccal cells of cancer patients receiving carboplatin and cisplatin combination chemotherapy, as determined by an immunocytochemical method: interindividual variation and correlation with disease response. Cancer Res., 53, 5669-5675.
11. Fichtinger-Schepman, A.M.J., Baan, R.A., Luiten-Schuite, A., Van Dijk, M. and Lohman, P.H.M. (1985) Immunochemical quantitation of adducts induced in DNA by cis-diamminedichloroplatinum(II) and analysis of adduct-related DNA unwinding. Chem.-Biol. Interactions, 55, 275-288.
12. Fichtinger-Schepman, A.M.J., Van Oosterom, A.T., Lohman, P.H.M. and Berends, F. (1987) cis-Diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminodichloroplatinum(II). Cancer Res., 47, 3000-3004.
13. 32P-postlabelling assay for DNA adducts induced by cis-diamminedichloroplatinum(II). Cancer Lett., 83, 129-137.
14. 32P-postlabelling assay for cisplatin-DNA adducts. Carcinogenesis, 15, 2829-2834.
15. Fichtinger-Schepman, A.M.J., Van der Veer, J.L., Lohman, P.H.M. and Reedijk, J. (1984) A simple method for the inactivation of monofunctionally DNA-bound cis-diamminedichloroplatinum (II). J. Inorg. Biochem., 21, 103-112.
16. Fichtinger-Schepman, A.M.J., Lohman, P.H.M. and Reedijk, J. (1982) Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum(II) with DNA, by anion-exchange chromatography after enzymatic degradation. Nucleic Acids Res., 10, 5345-5356.
17. Fichtinger-Schepman, A.M.J., Van Dijk-Knijnenburg, H.C.M., Dijt, F.J., Van der Velde-Visser, S.D., Berends, F. and Baan, R.A. (1995) Effects of thiourea and ammonium bicarbonate on the formation and stability of bifunctional cisplatin-DNA adducts: consequences for the accurate quantification of the adducts in (cellular) DNA. J. Inorg. Biochem., 58, 177-191.
18. Benard, J., Da Silva, J., De Blois, M.-C., Boyer, P., Duvillard, P., Chiric, E. and Riou, G. (1985) Characterization of a human ovarian adenocarcinoma line, IGROV-1, in tissue culture and in nude mice. Cancer Res., 45, 4970-4979.
19. Braakhuis, B.J.M., Kegel, A. and Welters, M.J.P. (1994) The growth inhibiting effect of docetaxel (taxotere) in head and neck squamous cell carcinoma xenografts. Cancer Lett., 81, 151-154.
20. Miller, S.A., Dykes, D.D. and Polsky, H.F. (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res., 16, 1215-1218.
21. Jain, R. and Sharma, M. (1993) Fluorescence postlabelling assay of DNA damage induced by N-methyl-N-nitrosourea. Cancer Res., 53, 2771-2774.
22. Kelman, D.J., Lilga, K.T. and Sharma, M. (1988) Synthesis and application of fluorescent labelled nucleotides to assay DNA damage. Chem.-Biol. Interactions, 66, 85-100.
23. Sharma, M., Jain, R. and Isac, T.V. (1991) A novel technique to assay adducts of DNA induced by anticancer agent cis-diamminedichloroplatinum(II). Bioconjugate Chem., 2, 403-406.
24. Moschel, R.C. and Leonard, N.J. (1976) Fluorescent modification of guanine. Reaction with substituted malondialdehydes. J. Org. Chem., 41, 294-300.
25. Shuker, D.E.G., Durand, M.J. and Molko, D. (1993) Fluorescent postlabelling of modified DNA bases. In Phillips, D.H., Castegnaro, M. and Bartsch, H. (ed.) Postlabelling Methods for the Detection of DNA Adducts. International Agency for Research on Cancer IARC, Lyon, pp. 227-230.
26. Eastman, A. (1986) Reevaluation of interaction of cis-dichloro(ethylene-diammine)platinum(II) with DNA. Biochemistry, 25, 3912-3915.