HLA-B*2707 peptide motif: Tyr C-terminal anchor is not shared by all disease-associated subtypes

Immunogenetics

Volumn 47, Issue 1, 1997, Pages 103-105

  Tieng, Vannary ^a   Dulphy, Nicolas ^a   Boisgérault, Florence ^a   Tamouza, Ryad ^a   Charron, Dominique ^a   Toubert, Antoine ^a  

^a SAINT LOUIS HOSPITAL   (France)

Author keywords

HLA B27; MHC peptide elution; MHC peptide motif; Spondyloarthropathies

Indexed keywords

HLA B ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; HLA B27 ANTIGEN; TYROSINE;

AMINO ACID SEQUENCE; ANTIBODY COMBINING SITE; ARTICLE; CARBOXY TERMINAL SEQUENCE; GENETIC SUSCEPTIBILITY; HUMAN; PRIORITY JOURNAL; RACE DIFFERENCE; SPONDYLOARTHROPATHY; CELL LINE; CHEMISTRY; GENETICS; IMMUNOLOGY; RHEUMATIC DISEASE;

AMINO ACID SEQUENCE; CELL LINE; HLA-B27 ANTIGEN; HUMANS; PEPTIDES; RHEUMATIC DISEASES; TYROSINE;

EID: 0031283451     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050334     Document Type: Article

References (13)

1. D'Amato, M., Fiorillo, M. T., Carcassi, C., Mathieu, A., Zuccarelli, A., Bitti, P. P., Tosi, R., and Sorrentino, R. Relevance of residue 116 of HLA-B27 in determining susceptibility to ankylosing spondylitis. Eur J Immunol 25: 3199-3201, 1995
2. Boisgérault, F., Tieng, V., Stolzenberg, M. C., Dulphy, N., Khalil, I., Tamouza, R., Charron, D., and Toubert, A. Differences in endogenous peptides presented by HLA-B*2705 and B*2703 allelic variants. Implications for susceptibility to Spondylarthropathies. J Clin Invest 98: 2764-2770, 1996
3. Choo, S. Y., Fan, L. A., and Hansen, J. A. A novel HLA-B27 allele maps B27 allospecificity to the region around position in the alpha 1 domain. J Immunol 147: 174-180, 1991
4. Falk, K., Rötzschke, O., Stefanović, S., Jung, G., and Rammensee, H.-G. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351: 290-296, 1991
5. Fiorillo, M. T., Meadows, L., D'Amato, M., Shabanowitz, J., Hunt, D. F., Appella, E., and Sorrentino, R. Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes. Eur J Immunol 27: 368-373, 1997
6. García, F., Marina, A., and López de Castro, J. A. Lack of carboxyl-terminal tyrosine distinguishes the B*2706-bound peptide repertoire from those of B*2704 and other HLA-B27 subtypes associated with ankylosing spondylitis. Tissue Antigens 49: 215-221, 1997
7. Gonzalez-Roces, S., Alvarez, M. V., Gonzalez, S., Dieye, A., Makni, H., Woofield, D. G., Housan, L., Konenkov, V., Abbadi, M. C., Grunnet, N., Coto, E., and Löpez-Larrea, C. HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis. Tissue Antigens 49: 116-123, 1997
8. Jardetzky, T. S., Lane, W. S., Robinson, R. A., Madden, D. R., and Wiley, D. C. Identification of self peptides bound to purified HLA-B27. Nature 353: 326-329, 1991
9. López-Larrea, C., Sujirachato, K., Mehra, N. K., Chiewsilp, P., Isarangkura, D., Kanga, U., Dominguez, O., Goto, E., Pena, M., Setién, F., and Gonzalez-Roces, S. HLA-B27 subtypes in Asian patients with ankylosing spondylitis. Evidence for new associations. Tissue Antigens 45: 169-176, 1995
10. Madden, D. R., Gorga, J. C., Strominger, J. L., and Wiley, D. C. The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. Nature 353: 321-325, 1991
11. Rammensee, H-G., Friede, T., and Stefanovic, S. MHC ligands and peptide motifs: first listing. Immunogenetics 41: 178-228, 1995
12. Ren, E. C., Koh, W. H., Sim, D., Boey, M. L., Wee, G. B., and Chan, S. H. Possible protective role of HLA-B*2706 for ankylosing spondylitis. Tissue Antigens 49: 67-69, 1997
13. Rötzschke, O., Falk, K., Stefanović, S., Gnau, V., Jung, G., and Rammensee, H.-G. Dominant aromatic/aliphatic C-terminal anchor in HLA-B*2702 and HLA-B*2705 peptide motifs. Immunogenetics 39: 74-77, 1994