Effect of intensive IV + oral magnesium supplementation on circulating ion levels, lipid parameters and metabolic control in Mg-depleted insulin-dependent diabetic patients (IDDM)

Magnesium Research

Volumn 10, Issue 2, 1997, Pages 135-141

  De Leeuw, I ^a   Engelen, W ^a   Vertommen, J ^a   Nonneman, L ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Insulin dependent diabetes; Ionized mg; Mg depletion; Mg supplementation

Indexed keywords

MAGNESIUM;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIET THERAPY; ERYTHROCYTE; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INTRAVENOUS DRUG ADMINISTRATION; LIPID METABOLISM; MAGNESIUM DEFICIENCY; MALE; METABOLISM; MIDDLE AGED; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; DIABETES MELLITUS, TYPE 1; DIETARY SUPPLEMENTS; ERYTHROCYTES; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; LIPID METABOLISM; MAGNESIUM; MAGNESIUM DEFICIENCY; MALE; MIDDLE AGED;

EID: 0031283404     PISSN: 09531424     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Mather, H.M., Nisbet, J.A., Burton, G.H. et al. (1979): Hypomagnesia in diabetes. Clin. Chim. Acta. 95, 235-242.
2. Gunn, I.R. & Burns, E. (1987): Plasma ultrafilterable magnesium in insulin dependent diabetics. J. Clin. Pathol. 40, 294-297.
3. Ewald, U., Gebre-Mehdin, M. & Tuvemo, T. (1983) Hypomagnesia in diabetic children. Acta Paediatr. Scand. 72, 367-371.
4. McNair, P., Christensen, M.S., Christiansen, C. et al (1982): Renal hypomagnesemia in human diabetes mellitus: its relation to glucose homeostasis. Eur. J. Clin. Invest. 12, 81-85.
5. Djurhuus, M.S., Skøtt, P. & Hother-Nielsen, O. (1995): Insulin increases renal Mg excretion: a possible cause of Mg depletion in hyperinsulinaemic states. Diabet. Med. 12, 664-669.
6. Rayssiguier, Y. (1977): Hypomagnesemia resulting from adrenaline infusion in ewes: its relation to lipolysis. Horm. Metab. Res. 9, 309-314.
7. Sjögren, A., Floren, C-H. & Nilsson, A. (1986): Magnesium deficiency in IDDM is related to the level of glycosylated hemoglobin. Diabetes 35, 459-463
8. Wallach, S. & Lawrence Verch, R. (1987): Tissue magnesium content in diabetic rats. Magnesium 6, 302-306.
9. Anwana, AB. & Garland, H.O. (1990): Renal calcium and magnesium handling in experimental diabetes mellitus in the rat. Acta. Endocrinol. 122, 479-486
10. Rasmussen, H.S., Norregrad, P. & Lindeneg, O. (1986): Intravenous magnesium infusion in acute myocardial infarction. Lancet 1, 234.
11. Seelig, M.S., Heggtveit, H.A. (1974): Magnesium interrelationships in ischemic heart disease: a review. Am. J. Clin. Nutr. 27, 59-79.
12. Ceriello, A., Giugliano D., Dello Russo P.et al (1982): Hypomagnesemia in relation to diabetes retinopathy. Diabetes Care 5, 558-559.
13. Fujii, S., Takemura, T., Wada, M. et al. (1982): Magnesium levels in plasma, erythrocyte and urine in patients with diabetes mellitus. Horm. Metab. Res. 14, 161-162.
14. Vanroelen, W., Van Gaal, L. & Van Rooy, P. (1985): Serum and erythrocyte magnesium levels in type 1 and type 2 diabetics. Acta Diabetol. Lat. 22, 185-190.
15. Ewald, U. & Tuvemo, T. (1985): Reduced vascular reactivity in diabetic children and its relation to diabetic control. Acta Paediatr. Scand. 74, 77-85.
16. Cohen, L., Laor, A. & Kitzes, R. (1984): Reversible retinal vasospasm in magnesium-treated hypertension despite no significant change in blood pressure. Magnesium 3, 159-163.
17. Engelen, W,. Bouten, A. & De Leeuw, I. (1996): Does magnesium play a role in the natural history of polyneuropathy in IDDM? Magnes. Res. 9, 245-246.
18. 2+ on Na+-dependent inositol transport. Diabetes 41, 35-39.
19. De Leeuw, I. (1989): Magnesium status in diabetes mellitus: old and new facts. In: Mg in health and disease. eds.Y Itokawa & J. Durlach. London: John Libbey & Co Ltd, pp. 343-348.
20. DCCT Study Group (1983): The effect of diabetes on the development and progression of longterm complications in IDDM. N. Engl. J. Med. 329, 977-986.
21. Durlach, J. (1985): Les modes d'exploration du magnésium. In: Le magnéésium en pratique clinique, ed. J. Durlach, Paris: J.B. Baillière, pp. 45-68.
22. De Leeuw, I., Vertommen, J. & Abs, R. (1978): The Mg content of the trabecular bone in diabetic subjects. Biomedicine 29, 16-17.
23. Ryzen, E., Elbaum, N., Singer, F.R. et al (1985): Parenteral magnesium tolerance testing in the evaluation of magnesium deficiency. Magnesium 4, 137-147.
24. Rude, R. (1993): Magnesium metabolism and deficiency. Endocrinol. Metab. Clin. North Am. 22, 377-395.
25. Altura, B.T., Burack, J L., Cracco, R.Q. et al (1994): Clinical studies with the NOVA ISE for iMg. Scand. J. Clin. Lab. Invest. 54, (suppl. 217), 53-67.
26. American Diabetes Association (1992): Magnesium supplementation in the treatment of diabetes Diabetes Care 15, 1065-1067.
27. Paolisso, G., Sgambato, S., Pizza, G. et al. (1989): Improved insulin response and action by chronic magnesium administration in aged NIDDM subjects. Diabetes Care 12, 265-269.
28. Paolisso, G., Scheen, A., Cozzolino, D. et al. (1994): Changes in glucose turnover parameters and improvement of glucose oxidation after 4 week magnesium administration in elderly non-insulindependent (type 2) diabetic patients. J. Clin. Endocrinol. Metab. 78, 1510-1514
29. Nadler, J.L., Malayan, S., Luong, H. et al. (1992): Intracellular free magnesium deficiency plays a key role in increased platelet reactivity in type 2 diabetes mellitus. Diabetes Care 15, 835-841.
30. Eibl, N.L., Kopp, H.P., Nowak, H.R. et al. (1995): Hypomagnesuria in type 2 diabetes: effect of a 3 month replacement therapy. Diabetes Care 18, 188-192.
31. Durlach, J., Durlach, V., Bac, P. et al. (1994): Magnesium and therapeutics. Magnes. Res. 7, 313-328.
32. Brookes, C.I.O. & Fry, C.H. (1993): Ionised magnesium and calcium in plasma from healthy volunteers and patients undergoing cardiopulmonary bypass. Br. Heart J. 69, 404-408.
33. Meludu, S.C., Adeniyi, F.A.A. & Taylor, G.O.L. (1995): Plasma and erythrocyte Mg response to oral glucose loading in healthy Nigerians. Magnes. Res. 8 (suppl. 1), 53