Protein phosphorylation and the regulation of cell - Cell junctions in brain endothelial cells

Heart and Vessels

Volumn 12, Issue SUPPL. 12, 1997, Pages 106-109

  Staddon, James ^a   Ratcliffe, Marianne ^a   Morgan, Louise ^a   Hirase, Tetsuaki ^a   Smales, Caroline ^a   Rubin, Lee ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Brain; Endothelium; Junctions; Signaling

Indexed keywords

MEMBRANE PROTEIN; TYROSINE;

BLOOD BRAIN BARRIER; BRAIN; BRAIN CAPILLARY; CELL JUNCTION; CONFERENCE PAPER; ENDOTHELIUM CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TIGHT JUNCTION; VASCULAR ENDOTHELIUM; ANIMAL; CELL MEMBRANE PERMEABILITY; HUMAN; METABOLISM; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD-BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM, VASCULAR; HUMANS; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TYROSINE;

EID: 0031283343     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (27)

1. Schinkel AH, Smit JJM, van Tellingen O, Beijnen, JH, Wagenaar E, van Deemter L, Mol CAAM, van der Walk MA, Robanus-Maandag EC, te Riele HPJ, Berns AJM, Borst P (1994) Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77:491-502
2. Risau W (1995) Differentiation of endothelium. FASEB J 9:926-933
3. Gumbiner BM (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84:345-357
4. Stewart PA, Wiley MJ (1981) Developing nervous tisue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail-chick transplantation chimeras. Dev Biol 84:183-192
5. Janzer RC, Raff MC (1987) Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 325:253-257
6. Anderson JM, Van Itallie CM (1995) Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Physiol 269:G467-G475
7. Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S, Tuskita S (1993) Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 123:1777-1788
8. Ando-Akatsuka Y, Saitou Hirase T, Kishi M, Sakakibara A, Itoh M, Yonemura S, Furuse M, Tsukita S (1996) Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol 133:43-47
9. Hirase T, Staddon JM, Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M, Fujimoto K, Tsukita SH, Rubin LL (1997) Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci 110:1603-1613
10. Anderson JM (1996) Cell signalling: MAGUK magic. Curr Biol 6:382-384
11. Staddon JM, Herrenknecht K, Smales C, Rubin LL-(1995) Evidence that tyrosine phosphorylation may increase tight junction permeability. J Cell Sci 108:609-619
12. Van Itallie CM, Balda MS, Anderson JM (1995) Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells. J Cell Sci 108:1735-1742
13. Takeda H, Nagafuchi A, Yonemura S, Tsukita S, Behrens J, Birchmeier W, Tsukita S (1995) V-src shifts the cadherin-based cell adhesion from the strong to the weak state and β-catenin is not required for the shift. J Cell Biol 131:1839-1847
14. Kurihara H, Anderson JM, Farquhar MG (1995) Increased tyrosine phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes. Am J Physiol 268:F514-F524
15. Gumbiner BM, Simons K (1986) A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide. J Cell Biol 102:457-468
16. Dejana E, Corada M, Lampugnani MG (1995) Endothelial cell-to-cell junctions. FASEB J 9:910-918
17. Lampugnani MG, Corada M, Caveda L, Breviario F, Ayalon O, Geiger B, Degana E (1995) The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol 129:203-217
18. Staddon JM, Smales C, Schulze C, Esch FS, Rubin LL (1995) p120, a p120-related protein (p100) and the cadherin/catenin complex. J Cell Biol 130:369-381
19. Tsukita S, Oishi K, Akiyama T, Yamanishi Y, Yamamoto T, Tsukita S (1991) Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junction where the level of tyrosine phosphorylation is elevated. J Cell Biol 113:867-879
20. Maher PA, Pasquale EB (1988) Tyrosine phosphorylated tissues in different tissues during chick embryo development. J Cell Biol 106:1747-1755
21. Achen MG, Clauss M, Schnüren H, Risau W (1995) The non-receptor tyrosine kinase lyn is localised in the developing murine blood-brain barrier. Differentiation 59:15-24
22. Kanner SB, Reynolds AB, Vines RR, Parsons JT (1990) Monoclonal antibodies to individual tyrosine phsophorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci USA 87:3328-3332
23. Peifer MS, Berg S, Regnolds AB (1994) A repeating amino acid motif shared by proteins with diverse cellular roles. Cell 76:789-791
24. cas associates with E-cadherin complexes. Mol Cell Biol 14:8333-8342
25. Shibamoto S, Hayakawa M, Takeuchi K, Hori T, Miyazawa K, Kitamura N, Johnson KR, Wheelock MJ, Matsuyoshi N, Takeichi M, Ito F (1995) Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes. J Cell Biol 128:949-957
26. Rubin LL, Hall DE, Porter S, Barbu K, Cannon C, Horner HC, Janatpour M, Liaw CW, Manning K, Morales J, Tanner LI, Tomaselli KJ, Bard F (1991) A cell culture model of the blood-brain barrier. J Cell Biol 115:1725-1735
27. Schulze C, Rubin LL, Staddon JM (1997) Lysophosphatidic acid increases tight junction permeability in cultured brain endothelial cells. J Neurochem 68:991-1000