Amount of calcium in the sarcoplasmic reticulum: Influence on excitation-contraction coupling in heart muscle

Heart and Vessels

Volumn 12, Issue SUPPL. 12, 1997, Pages 44-49

  Santana, Luis F ^a   Gómez, Ana M ^a   Kranias, Evangelina G ^b   Jonathan Lederer, W ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Calcium; Confocal; Contraction; Heart; Phospholamban

Indexed keywords

CALCIUM; PHOSPHOLAMBAN; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM BINDING PROTEIN; CALCIUM CHANNEL;

ANIMAL CELL; CALCIUM CELL LEVEL; CONFERENCE PAPER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; GENETIC ENGINEERING; HEART CONTRACTION; HEART EXCITATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; CYTOLOGY; HEART; HEART MUSCLE; HEART VENTRICLE; IMAGE PROCESSING; KINETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; CELLS, CULTURED; HEART; HEART VENTRICLES; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MYOCARDIAL CONTRACTION; MYOCARDIUM; SARCOPLASMIC RETICULUM;

EID: 0031283324     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (24)

1. Fabiato A (1983) Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol 245:C1-14
2. Niggli E, Lederer WJ (1990) Voltage-independent calcium release in heart muscle. Science 250:565-568
3. i during excitation-contraction coupling in cardiac myocytes. Biophysi J 67:1942-1956
4. Cannell MB, Cheng H, Lederer WJ (1995) The control of calcium release in heart muscle. Science 268:1045-1049
5. Cheng H, Cannell MB, Lederer WJ (1994) Propagation of excitation-contraction coupling into ventricular myocytes. Pflugers Arch 428:415-417
6. i waves in cardiac myocytes. Am J Physiol 270:C148-159
7. Cheng H, Lederer WJ, Cannell MB (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262:740-744
8. López-López JR, Shacklock PS, Balke CW, Wier WG (1995) Local calcium transients triggered by single L-type calcium channel currents in cardiac cells. Science 268:1042-1045
9. 2+ sparks and local control theories for cardiac excitation-contraction coupling. Circ Res 78:166-171
10. 2+-ATPase protein levels. Circ Res 77:759-764
11. Luo W, Grupp IL, Harrer J, Ponniah S, Grupp G, Duffy JJ, Doetschman T, Kranias EG (1994) Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res 75:401-409
12. Luo W, Wolska BM, Grupp IL, Harrer JM, Haghighi K, Ferguson DG, Slack JP, Grupp G, Doetschman T, Solaro R.J. & Kranias E.G. (1996) Phospholamban gene dosage effects in the mammalian heart. Circ Res 79:839-847
13. 2+ channel and α-adrenergic stimulation in wild-type and phospholamban-deficient mouse cardiac myocytes. J Mol Cell Cardiol 28:A120
14. Wolska BM, Stojanovic MO, Luo W, Kranias EG, Solaro RJ (1996) Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular calcium under basal conditions and beta-adrenergic stimulation. Am J Physiol 271:H391-397
15. Simmerman HK, Collins JH, Theibert JL, Wegener AD, Jones LR (1986) Sequence analysis of phospholamban: identification of phosphorylation sites and two major structural domains. J Biol Chem 261:13333-13341
16. 2+-ATPase activity in guinea pig ventricles. J Biol Chem 258:464-471
17. Santana LF, Kranias EG, Lederer WJ (1997) Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. J Physiol (Lond) 503:21-29
18. 2+ content in cardiac myocytes. Am J Physiol 268:C1313-1319
19. 2+ influx during the cardiac action potential in guinea pigs ventricular myocytes. Circ Res 79:194-200
20. 2+ sparks in rat ventricular myocytes. J Physiol 462:575-581
21. Kass RS, Sanguinetti MC (1984) Inactivation of calcium channel current in the calf Purkinje fiber: evidence for voltage- and calcium-mediated mechanisms. J Gen Physiol 84:705-726
22. McDonald TF, Pelzer S, Trautwein W, Pelzer DJ (1994) Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev 74:365-507
23. 2+ buffering in guinea pig ventricular cardiomyocytes. Biophys J 72:175-187
24. 2+ channels and ryanodine receptors in cardiac myocytes. Proc Nat Acad Sci USA 92:121-125