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Volumn 51, Issue 10, 1997, Pages 413-416

Hypothetical reasons of the HIV1-AIDS 'tritherapy' failure. A challenging model

Author keywords

AIDS; HIV; Treatment failure; Tritherapy

Indexed keywords

ACRIFLAVINE; ELLIPTICINE DERIVATIVE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 0031282880     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(97)82318-9     Document Type: Editorial
Times cited : (5)

References (39)
  • 1
    • 85030304681 scopus 로고    scopus 로고
    • Les experts préconisent une trithérapie immédiate chez les personnes infectées par le virus du SIDA. Le comité dormont s'interroge sur la prescription des traitements en urgence
    • 9 October
    • Nau JY. Les experts préconisent une trithérapie immédiate chez les personnes infectées par le virus du SIDA. Le comité Dormont s'interroge sur la prescription des traitements en urgence. Le Monde 9 October 1997 :11
    • (1997) Le Monde , pp. 11
    • Nau, J.Y.1
  • 2
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4 T cell homeostasis and function in advanced HIV disease
    • Autran B, Carcelain G, Li TS. Positive effects of combined antiretroviral therapy on CD4 T cell homeostasis and function in advanced HIV disease. Science 1997; 277:112
    • (1997) Science , vol.277 , pp. 112
    • Autran, B.1    Carcelain, G.2    Li, T.S.3
  • 3
    • 2442723342 scopus 로고    scopus 로고
    • Treatment of human immunodeficiency virus infection with saquinavir, zidovudine and zalcitabine
    • Collier AC, Coombs RW, Schoenfeld DA et al. Treatment of human immunodeficiency virus infection with saquinavir, zidovudine and zalcitabine. N Engl J Med 1996;334:1011
    • (1996) N Engl J Med , vol.334 , pp. 1011
    • Collier, A.C.1    Coombs, R.W.2    Schoenfeld, D.A.3
  • 4
    • 0030317268 scopus 로고    scopus 로고
    • Neviparine, zidovudine and didanosine compared with zidovudine, and didanosine in patients with HIV, infection : A randomized, double-blind, placebo controlled trial
    • D'Aquila RT, Hughes MD, Johnson VD et al. Neviparine, zidovudine and didanosine compared with zidovudine, and didanosine in patients with HIV, infection : a randomized, double-blind, placebo controlled trial. Ann Intern Med 1996;124:1019
    • (1996) Ann Intern Med , vol.124 , pp. 1019
    • D'Aquila, R.T.1    Hughes, M.D.2    Johnson, V.D.3
  • 5
    • 85030304159 scopus 로고    scopus 로고
    • Infections à VIH : Les essais de trithérapie donnent des résultats encourageants
    • Jonas M. Infections à VIH : les essais de trithérapie donnent des résultats encourageants. Quotidien du Médecin 1996;5780:10
    • (1996) Quotidien du Médecin , vol.5780 , pp. 10
    • Jonas, M.1
  • 6
    • 85030307624 scopus 로고    scopus 로고
    • Les associations de lutte contre le SIDA s'inquiètent de la progression des résistances aux trithérapies
    • 18 September
    • Nau JY. Les associations de lutte contre le SIDA s'inquiètent de la progression des résistances aux trithérapies. Le Monde 18 September 1997:8
    • (1997) Le Monde , pp. 8
    • Nau, J.Y.1
  • 7
    • 85030306059 scopus 로고    scopus 로고
    • note
    • Action-traitement, Act Up Paris, Aides, Arcat-SIDA, Nova Dona, Sida Info, Solidarité Enfants SIDA, Vaincre le SIDA
  • 8
    • 0030879281 scopus 로고    scopus 로고
    • 1 infection and genome drug resistance
    • 1 infection and genome drug resistance. Lancet 1997;350:970
    • (1997) Lancet , vol.350 , pp. 970
    • Katzenstein, D.1
  • 9
    • 85030302492 scopus 로고    scopus 로고
    • SIDA, un bémol sur les trithérapies
    • Stolberg SG. SIDA, un bémol sur les trithérapies. Courrier International 1997;358:35
    • (1997) Courrier International , vol.358 , pp. 35
    • Stolberg, S.G.1
  • 10
    • 0030771938 scopus 로고    scopus 로고
    • The daunting challenge of keeping HIV supressed
    • Cohen J. The daunting challenge of keeping HIV supressed. Science 1997;277:32
    • (1997) Science , vol.277 , pp. 32
    • Cohen, J.1
  • 11
    • 0028084840 scopus 로고
    • Randomising means, not aims in clinical trials
    • Wider J. Randomising means, not aims in clinical trials. Lancet 1994;343:359
    • (1994) Lancet , vol.343 , pp. 359
    • Wider, J.1
  • 13
    • 0030767808 scopus 로고    scopus 로고
    • Unethical trials of interventions to reduce perinatal transmission of the human immunodeficiency virus in developing countries
    • Lurie P, Wolfe S. Unethical trials of interventions to reduce perinatal transmission of the human immunodeficiency virus in developing countries. N Engl J Med 1997;337:853-6
    • (1997) N Engl J Med , vol.337 , pp. 853-856
    • Lurie, P.1    Wolfe, S.2
  • 14
    • 85030305835 scopus 로고    scopus 로고
    • Arrêt des expériences américaines utilisant des placebos contre le SIDA en Afrique
    • 26-27 October
    • Nau JY. Arrêt des expériences américaines utilisant des placebos contre le SIDA en Afrique. Le Monde 26-27 October 1997:4
    • (1997) Le Monde , pp. 4
    • Nau, J.Y.1
  • 15
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995;373:117
    • (1995) Nature , vol.373 , pp. 117
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 17
    • 0026036042 scopus 로고
    • Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes
    • Larder BA, Kellam P, Kemp SD. Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes. AIDS 1991;5:137
    • (1991) AIDS , vol.5 , pp. 137
    • Larder, B.A.1    Kellam, P.2    Kemp, S.D.3
  • 18
    • 0027300873 scopus 로고
    • Pol mutation conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo
    • Eron JJ, Chaw YK, Caliendo AM et al. Pol mutation conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo. Antimicrob Agents Chemother 1993;37:1480
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1480
    • Eron, J.J.1    Chaw, Y.K.2    Caliendo, A.M.3
  • 19
    • 0028210191 scopus 로고
    • In vivo eradication of Friend virus as an experimental HIV-model, by combination of zidovudine, acriflavine and an ellipticine analogue. Possible application to the treatment of human pre-AIDS
    • Mathé G, Pontiggia P, Bourut C et al. In vivo eradication of Friend virus as an experimental HIV-model, by combination of zidovudine, acriflavine and an ellipticine analogue. Possible application to the treatment of human pre-AIDS. Biomed Pharmacother 1994;48:51
    • (1994) Biomed Pharmacother , vol.48 , pp. 51
    • Mathé, G.1    Pontiggia, P.2    Bourut, C.3
  • 20
    • 0001587762 scopus 로고
    • Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotropic virus type III/ lymphadenopathy virus-associated virus (HTLV-III/LAV) by 2' .3-dideoxynucleosides
    • Mitsuya H, Broder S. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotropic virus type III/ lymphadenopathy virus-associated virus (HTLV-III/LAV) by 2' .3-dideoxynucleosides. Proc Natl Acad Sci USA 1986;83:1911
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1911
    • Mitsuya, H.1    Broder, S.2
  • 21
    • 0024403992 scopus 로고
    • Amino-acridines action of Friend's retrovirus in relation to their molecular ionization
    • Mathé G, Chenu E, Bourut C et al. Amino-acridines action of Friend's retrovirus in relation to their molecular ionization. Biomed Pharmacother 1989;43:235
    • (1989) Biomed Pharmacother , vol.43 , pp. 235
    • Mathé, G.1    Chenu, E.2    Bourut, C.3
  • 22
    • 0027714938 scopus 로고
    • A screening model of anti-HIV non AZT cross resistance virostatics
    • Mathé G, Pontiggia P. A screening model of anti-HIV non AZT cross resistance virostatics. Biomed Pharmacother 1993;47:461
    • (1993) Biomed Pharmacother , vol.47 , pp. 461
    • Mathé, G.1    Pontiggia, P.2
  • 23
    • 0027739835 scopus 로고
    • The in vivo effect of ellipticine analogues on the blood concentration of Friend's virus : A murine model for studying anti-HIV drugs
    • Mathé G, Chenu E, Bourut C et al. The in vivo effect of ellipticine analogues on the blood concentration of Friend's virus : a murine model for studying anti-HIV drugs. Biomed Pharmacother 1993;47:457
    • (1993) Biomed Pharmacother , vol.47 , pp. 457
    • Mathé, G.1    Chenu, E.2    Bourut, C.3
  • 24
    • 0030453903 scopus 로고    scopus 로고
    • Lymphangiography study of pelvic adenotherapy regression in phase II trial of methyl-hydroxy-ellipticine in HIV 1-AIDS complex
    • Mathé G, Hallard M, Pontiggia P. Lymphangiography study of pelvic adenotherapy regression in phase II trial of methyl-hydroxy-ellipticine in HIV 1-AIDS complex. Biomed Pharmacother 1996;50:510
    • (1996) Biomed Pharmacother , vol.50 , pp. 510
    • Mathé, G.1    Hallard, M.2    Pontiggia, P.3
  • 25
    • 0025865792 scopus 로고
    • Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative
    • Fosse P, René B, Le Bret M et al. Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative. Nucleic Acids Res 1991;19:2861
    • (1991) Nucleic Acids Res , vol.19 , pp. 2861
    • Fosse, P.1    René, B.2    Le Bret, M.3
  • 27
    • 0029847538 scopus 로고    scopus 로고
    • Aids therapy with two, three or four agent combinations, applied in short sequences, differing from each other by drug rotation. I. First of two parts : A phase I trial equivalent, concerning five virostatics
    • Mathé G, Pontiggia P, Orbach-Arbouys S. Aids therapy with two, three or four agent combinations, applied in short sequences, differing from each other by drug rotation. I. First of two parts : a phase I trial equivalent, concerning five virostatics. Biomed Pharmacother 1996;50:220
    • (1996) Biomed Pharmacother , vol.50 , pp. 220
    • Mathé, G.1    Pontiggia, P.2    Orbach-Arbouys, S.3
  • 28
    • 0030300225 scopus 로고    scopus 로고
    • Will killing the last HIV 1 particle cure AIDS patients? II : Second part. Decrease of VL and of T-suppressor cells, and increase of the cytotoxic cells, without effect on CD4, after use of 10 virostatics applied in 3 or 4 drug combinations of different sequences. The time for CD4 immunotherapy ?
    • Mathé G, Colasanté U, Morette C et al. Will killing the last HIV 1 particle cure AIDS patients? II : Second part. Decrease of VL and of T-suppressor cells, and increase of the cytotoxic cells, without effect on CD4, after use of 10 virostatics applied in 3 or 4 drug combinations of different sequences. The time for CD4 immunotherapy ? Biomed Pharmacother 1996;50:473
    • (1996) Biomed Pharmacother , vol.50 , pp. 473
    • Mathé, G.1    Colasanté, U.2    Morette, C.3
  • 30
    • 0029028067 scopus 로고
    • Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
    • Larder BA, Kemp SA, Harrigan PRI. Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science 1995;269:696-699
    • (1995) Science , vol.269 , pp. 696-699
    • Larder, B.A.1    Kemp, S.A.2    Harrigan, P.R.I.3
  • 32
    • 0029644513 scopus 로고
    • Safety and activity of saquinavir in HIV infection
    • Kitchen VS, Skinner C, Arigoshi K et al. Safety and activity of saquinavir in HIV infection. Lancet 1995;345:952-5
    • (1995) Lancet , vol.345 , pp. 952-955
    • Kitchen, V.S.1    Skinner, C.2    Arigoshi, K.3
  • 33
    • 0028846165 scopus 로고
    • A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV 1 protease. European Australian Collaborative Ritonavir Group
    • Danner SA, Carr A, Leonard JM et al. A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV 1 protease. European Australian Collaborative Ritonavir Group. N Engl J Med 1995;333: 1528-33
    • (1995) N Engl J Med , vol.333 , pp. 1528-1533
    • Danner, S.A.1    Carr, A.2    Leonard, J.M.3
  • 34
    • 0028222149 scopus 로고
    • L-735, 524 : An orally bioavailable human immunodeficiency virus type 1 protease inhibitor
    • Vacca JP, Dorsey BD, Schleif WA et al. L-735, 524 : an orally bioavailable human immunodeficiency virus type 1 protease inhibitor. Proc Natl Acad Sci USA 1994;91:4096-100
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4096-4100
    • Vacca, J.P.1    Dorsey, B.D.2    Schleif, W.A.3
  • 35
    • 0031282881 scopus 로고    scopus 로고
    • Combinations of three and four HIV 1 virostatics applied in short sequences differing from each other by drug rotation. I-Result of the viral load and on the CD4 number of a preliminary trial
    • Mathé G, Morette C, Hallard M et al. Combinations of three and four HIV 1 virostatics applied in short sequences differing from each other by drug rotation. I-Result of the viral load and on the CD4 number of a preliminary trial. Biomed Pharmacother 1997;51:
    • (1997) Biomed Pharmacother , vol.51
    • Mathé, G.1    Morette, C.2    Hallard, M.3
  • 36
    • 85030306060 scopus 로고    scopus 로고
    • GvH or autologous GvH-like in HIV 1-AIDS complex pathophysiology ?
    • Milwaukee, WI, September 13
    • Mathé G, GvH or autologous GvH-like in HIV 1-AIDS complex pathophysiology ? New directions in blood cell and bone marrow transplants. Milwaukee, WI, September 13, 1997
    • (1997) New Directions in Blood Cell and Bone Marrow Transplants
    • Mathé, G.1
  • 39
    • 0007883436 scopus 로고
    • Essai de traitement de la leucemie de Charlotte Friend par la greffe de cellules hématopoietiques de donneurs isogéniques vaccinés contre le virus
    • Mathé G, Amiel JL, Friend C. Essai de traitement de la leucemie de Charlotte Friend par la greffe de cellules hématopoietiques de donneurs isogéniques vaccinés contre le virus. Bull Cancer 1962:49-416
    • (1962) Bull Cancer , pp. 49-416
    • Mathé, G.1    Amiel, J.L.2    Friend, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.