Heparin clearance profiles after systemic anticoagulation using a heparin removal device system

ASAIO Journal

Volumn 43, Issue 6, 1997, Pages 922-926

  Tao, Weike ^a   Callahan, Jon D ^b   Vertrees, Roger A ^a   Brunston Jr , Robert L ^a   Deyo, Donald J ^a   Mcrea, James C ^b   Zwischenberger, Joseph B ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b University of New Mexico School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CARDIOLOGY; DRUG PRODUCTS; DRUG THERAPY; HEALTH RISKS; HEMODYNAMICS; MATHEMATICAL MODELS; PATIENT TREATMENT;

CARDIOPULMONARY BYPASS; FIRST ORDER EXPONENTIAL DEPLETION; HEPARIN; HEPARIN REMOVAL DEVICE SYSTEM; PROTAMINE; SYSTEMIC ANTICOAGULATION;

BIOMEDICAL EQUIPMENT;

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; HEPARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; BODY WEIGHT; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; DEVICE; DRUG BLOOD LEVEL; DRUG CLEARANCE; EXTRACORPOREAL CIRCULATION; FEMALE; HEPARINIZATION; INTRAVENOUS DRUG ADMINISTRATION; MATHEMATICAL MODEL; NONHUMAN; SWINE;

EID: 0031282387     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002480-199711000-00014     Document Type: Article

References (9)

1. Weiler JM, Freiman P, Sharath MD, et al: Serious adverse reactions to protamine sulfate: are alternatives needed? J Allergy Clin Immunol 75: 297-303, 1985.
2. Weiss ME, Adkinson NF Jr: Allergy to protamine. Clin Rev Allergy 9: 339-355, 1991.
3. Schapira M, Christman BW: Neutralization of heparin by protamine: time for a change? Circulation 82: 1877-1879, 1990.
4. Al-Mondhiry H, Pierce WS, Basarab RM: Protamine-induced thrombocytopenia and leukopenia. Thromb Haemost 53: 60-64, 1985.
5. Lowenstein E, Zapolm WM: Protamine reactions, explosive mediator release, and pulmonary vasoconstriction. Anesthesiology 73: 373-375, 1990.
6. Ma X, Mohammad SF, Kim SW: Heparin removal from blood using poly(L-lysine) immobilized hollow fiber. Biotechnol Bioeng 40: 530-536, 1992.
7. Vertrees RA, Zwischenberger JB, McRea JC, Tao W, Kurusz M, Conti VR: Reversal of anticoagulation without protamine using a heparin removal device after cardiopulmonary bypass. ASAIO J 40: M560-M564, 1994.
8. Conti VR, Vertrees RA, Zwischenberger JB, Kurusz M: First clinical use of a heparin removal device: an alternative to protamine. J Thorac Cardiovasc Surg 109: 1015-1017, 1995.
9. Jusko WJ, Evans WE, Schentag JJ: Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring, San Francisco, Applied Therapeutics; 1980.