The phtE locus in the phaseolotoxin gene cluster has ORFs with homologies to genes encoding amino acid transferases, the AraC family of transcriptional factors, and fatty acid desaturases

Molecular Plant-Microbe Interactions

Volumn 10, Issue 8, 1997, Pages 947-960

  Zhang, Yuan Xin ^a,b   Patil, Suresh S ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PSEUDOMONAS; PSEUDOMONAS SYRINGAE; PSEUDOMONAS SYRINGAE PV. PHASEOLICOLA; SYNECHOCYSTIS;

EID: 0031282376     PISSN: 08940282     EISSN: None     Source Type: Journal    
DOI: 10.1094/MPMI.1997.10.8.947     Document Type: Article

References (66)

1. Aarts, M. G., Dirkse, W. G., Stiekema, W. J., and Pereira, A. 1993. Transposon tagging of a male sterility gene in Arabidopsis. Nature 363:715-717.
2. Alonso, B., and Rubio, V. 1989. Participation of ornithine aminotransferase in the synthesis and catabolism of ornithine in mice. Biochem. J. 259:131-138.
3. Altshul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
4. Aslamkhan, A. 1992. Enzymology of the biosynthesis of the peptide moiety of phaseolotoxin. M.S. thesis. University of Hawaii, Honolulu, HI.
5. Beckwith, J. 1987a. The operon: A historical account. Pages 1439-1443 in: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. G. C. Neidhardt, J. Ingrahm, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger, eds. American Society for Microbiology, Washington, D.C.
6. Beckwith, J. 1987b. The lactose operon. Pages 1444-1452. in: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. G. C. Neidhardt, J. Ingrahm, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger, eds. American Society for Microbiology, Washington, D.C.
7. Bhella, R. S., and MacKenzie, S. L. 1995. Nucleotide sequence of cDNA from Limnanthes douglasii L. encoding a Δ-15 linoleic acid desaturase. Plant. Physiol. 108:861
8. Billheimer, J. T., Carnevale, H. N., Leisinger, T., Eckhardt, T., and Jones, E. E. 1976. Ornithine-transaminase activity in Escherichia coli: Its identity with acetylornithine-transaminase. J. Bacteriol. 127: 1315-1323.
9. Bustos, S. A., and Schleif, R. F. 1993. Functional domains of the AraC protein. Proc. Natl. Acad. Sci. USA 90:5638-5642.
10. Calogero, S., Gardan, R., Glaser, P., Schweizer, J., Rapoport, G., and Debarbouille, M. 1994. RocR, a novel regulatory protein controlling arginine utilization in Bacillus subtilis, belongs to the NtrC/NifA family of transcriptional activators. J. Bacteriol. 176:1234-1241.
11. Cheesbrough, T. M. 1990. Decreased growth temperature increases soybean stearoyl-acyl carrier protein desaturase activity. Plant Physiol. 93:555-559.
12. Chen, P., Andersson, D. I., and Toth, J. R. 1994. The control region of the pdu/cob regulon in Salmonella typhimurium. J. Bacteriol. 176: 5474-5482.
13. 3-type family of Cytochrome c oxidases. J. Biol. Chem. 265: 11185-11192.
14. Cronan, J. E., Gennis, R. B., and Maloy, S. R. 1987. Cytoplasmic membrane. Pages 31-55 in: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. G. C. Neidhardt, J. Ingrahm, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger, eds. American Society for Microbiology, Washington, D.C.
15. Cronan, J. E., and Rock., C. O. 1987. Biosynthesis of membrane lipids. Pages 474-497 in: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. G .C. Neidhardt, J. Ingrahm, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger, eds. American Society for Microbiology, Washington, D.C.
16. Degols, G. 1987. Functional analysis of the regulatory region adjacent to the cargB gene of Saccharomyces cerevisiae. Nucleotide sequence, gene fusion experiments and cis-dominant regulatory mutation synthesis. Eur. J. Biochem. 169:193-200.
17. Degols, G., Jauniaux, J. C., and Waime, J. M. 1987. Molecular characterization of transposable-element-associated mutations that lead to constitutive L-ornithine aminotransferase expression in Saccharomyces cerevisiae. Eur. J. Biochem. 165:289-296.
18. Delauney, A. J., Hu, C. A. A., Kishor, P. B. K., and Verma, D. P. S. 1993. Cloning of ornithine delta-aminotransferase cDNA from Vigna aconitifolia by trans-complementation in Escherichia coli and regulation of proline biosynthesis. J. Biol. Chem. 268:18637-18678
19. Deretic, V., Konyecsni, W. M., Mohr, C. D., Martin, D. W., and Hibler, N. S. 1989. Common denominators of promoter control in Pseudomonas and other bacteria. Bio/technology 7:1249-1254.
20. Dilworth, D. D., and McCarrey, J. R. 1992. Single-step elimination of contaminating DNA prior to reverse transcriptase PCR. PCR Methods Appl. 1:279-282.
21. Dunkley, E. A., Jr., Clejan, S., and Krulwich, T. A. 1991. Mutants of Bacillus species isolated on the basis of protonophore resistance are deficient in fatty acid desaturase activity. J. Bacteriol. 173:7750-7755.
22. Frank, D. W., and Iglewski, B. H. 1991. Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme synthesis in Pseudomonas aeruginosa. J. Bacteriol. 173:6460-6468.
23. Gallegos, M. T., Michan, C., and Ramos, J. L. 1993. The XylS/AraC family of regulators. Nucleic Acids Res. 21:807-810.
24. Gardan, R., Rapoport, G., and Debarbouille, M. 1995. Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis. J. Mol. Biol. 249:843-856.
25. Gomez-Duarte, O. G., and Kaper, J. B. 1995. A plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli.. Infect. Immun. 63:1767-1776.
26. Hamada, T., Kodama, H., Nishimura, M., and Iba, K. 1994. Cloning of a cDNA encoding tobacco omega-3-fatty acid desaturase. Gene 147: 293-294
27. Hatziloukas, E., Panopoulos, N. J., Delis, S., Prosen, D., and Schaad, N. W. 1995. An open reading frame in the approximately 28-kb tox-argk gene cluster encodes a polypeptide with homology to fatty acid desaturase. Gene 166:83-87.
28. Heijne, G. 1987. Sequence Analysis in Molecular Biology. Academic Press, New York.
29. Heimberg, H., Boyen, A., Crabeel, M., and Glansdorff, N. 1990. Escherichia coli and Saccharomyces cerevisiae acetylornithine aminotransferase: Evolutionary relationship with ornithine aminotransferases. Gene 90:69-78.
30. Henikoff, S. 1984. Unidirectional digestion with ExoIII creates targeted breakpoints for DNA sequencing. Gene 28:351-359.
31. Hsu, L. C., Okamoto, M., and Snell, E. E. 1989. L-Histidinol phosphate aminotransferase from Salmonella typhimurium. Kinetic behavior and sequence at the pyridoxal-P binding site. Biochimie 71:477-489.
32. Inana, G., Totsuka, S., Redmond, M., Dougherty, T., Nagle, J., Shiono, T., Ohura, T., Kominami, E., and Katunuma, N. 1986. Molecular cloning of human ornithine aminotransferase mRNA. Proc. Natl. Acad. Sci. USA 83:1203-1207.
33. Innes, R. W., Bent, A. F., Kunkel, B. N., Bisgrove, S. R., and Staskawicz, B. J. 1993. Molecular analysis of avirulence gene avrRpt2 and identification of a putative regulatory sequence common to all known Pseudomonas syringae avirulence genes. J. Bacteriol. 175: 4859-4869.
34. Joerger, R. D., Jacobson, M. R., and Bishop, P. E. 1989. Two nifA-like genes required for expression of alternative nitrogenases by Azotobacter vinelandii. J. Bacteriol. 171:3258-3267.
35. Kamdar, H. V., Rowley, K. B., Clements, D., and Patil, S. S. 1991. Pseudomonas syringae pv. phaseolicola genomic clones harboring heterologous DNA sequences suppress the same phaseolotoxin-deficient mutants. J. Bacteriol. 173:1073-1079.
36. Kirsch, J. F., Eichele, G., Ford, G. C., Vincent, M. G., and Jansonius, J. N. 1984. Mechanism of action of asparate aminotransferase proposed on the basis of its spatial structure. J. Mol. Biol. 174:497-525.
37. Lin, J. W., Yu, K. Y., Chao, Y. F., and Weng, S. F. 1995. The lumQ gene is linked to the lumP gene and the lux operon in Photobacterium leiognathi. Biochem. Biophys. Res. Comm. 217:684-695.
38. Lipman, D. J., and Pearson, W. R. 1985. Rapid and sensitive protein similarity searches. Science 227:1435-1441.
39. Marahiel, M. A. 1992. Multidomain enzymes involved in peptide synthesis (minireview). FEBS Lett. 307:40-43.
40. Martin, J. F., and Liras, P. 1989. Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites. Annu. Rev. Microbiol. 43:173-206.
41. Misawa, N., Satomi, Y., Kondo, K., Yokoyama, A., Kajiwara, S., Saito, T., Ohtani, T., and Miki, W. 1995. Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster of astaxanthin biosynthetic pathway proposed at the gene level. J. Bacteriol. 177: 6575-6584.
42. Moore, R. E., Niemczura, W. P., Kwok, O. C. H., and Patil, S. S. 1984. Inhibitors of ornithine carbamoyltransferase from Pseudomonas syringae pv. phaseolicola: Revised structure of phaseolotoxin. Tetrahedron Lett. 25:3931-3934.
43. Ogierman, M. A., and Manning, P. A. 1992. Homology of TcpN, a putative regulatory protein of Vibrio cholerae, to the AraC family of transcriptional activators. Gene 116:93-97.
44. Okuley, J., Lightner, J., Feldman, K., Yadav, N., Larke, E., and Browse, J. 1994. Arabidopsis fad2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis. Plant Cell 6:147-158.
45. O'Reilly, M., and Devine, K. M. 1994. Sequence and analysis of the citrulline biosynthetic operon argC-F from Bacillus subtilis. Microbiology 140:1023-1025.
46. Oyama, R., Suzuki, M., Matsuzawa, T., and Titani, K. 1990. Complete amino acid sequence of rat kidney ornithine aminotransferase: Identity with liver ornithine aminotransferase. J. Biochem. 108:133-138.
47. Parker, L. L., and Hall, B. G. 1990. Characterization and nucleotide sequence of the cryptic cel operon of Escherichia coli K12. Genetics 124:455-471.
48. Paul, S. S. 1974. Toxins produced by phytopathogenic bacteria. Annu. Rev. Phytopathol. 12:259-279.
49. Raibaud, A., Zalacain, M., Holt, T. G., Tizard, R., and Thompson, C. J. 1991. Nucleotide sequence analysis reveals linked N-acetyl hydrolase, thioesterase, transport, and regulatory genes encoded by the bialaphos biosynthetic gene cluster of Streptomycin hygroscopicus. J. Bacteriol. 173:4454-4463.
50. Ream, W. 1989. Agrobacterium tumefaciens and interkingdom genetic exchange. Annu. Rev. Phytopathol. 27:583-618.
51. Rowley, K. B., Clements, D. E., Mandel, M., Humphreys, T., and Patil, S. S. 1993. Multiple copies of a DNA sequence from Pseudomonas syringae pv. phaseolicola abolish thermoregulation of phaseolotoxin production. Mol. Microbiol. 8:625-635.
52. Sakamoto, T., Wada, H., Nishida, I., Ohmore, M., and Murata, N. 1994. Identification of conserved domains in the delta-12 desaturases for cynobacteria. Plant Mol. Biol. 24:643-650.
53. Sanger, F., Nicklen, S., and Coulson, A. R. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
54. 54. Cell 62:945-954.
55. Singh, S., van der Heidi, T., McKinney, S., and Green, A. 1995. Nucleotide sequence of a cDNA from Brassica juncea encoding a microsomal Omega-6 desaturase (Accession No. x91139) (PGR 95-107). Plant Physiol. 109:1498.
56. Skriver, L., and Thompson, G. A., Jr. 1979. Temperature-induced changes in fatty acid unsaturation of Tetrahymena membranes do not require induced fatty acid desaturase synthesis. Biochem. Biophys. Acta 572:376-381.
57. To, K. Y., Lai, E. M., Lee, L. Y., Lin, T. P., Hung, C. H., Chen, C. L., Chang, Y. S., and Liu, S. T. 1994. Analysis of the gene cluster encoding carotenoid biosynthesis in Erwinia herbicola Eho 13. Microbiology 140:331-339.
58. δ-succinylornithine in ornithine catabolism of Pseudomonas aeruginosa. Arch. Microbiol. 150:400-404.
59. van der Wauven, C., and Stalon, V. 1985. Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia. J. Bacteriol. 164:882-886.
60. δ-acetylornithine 5-aminotransferase from Pseudomonas aeruginosa in arginine biosynthesis and arginine catabolism. J. Bacteriol. 122:799-809.
61. Wada, M., Fufunaga, N., and Sasaki, S. 1987. Effect of growth temperature on phospholipid and fatty acid compositions in a psychrotrophic bacterium, Pseudomonas sp. Strain E-3. Plant Cell Physiol. 28:1209-1217.
62. Wada, H., Combos, Z., and Murata, N. 1990. Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation. Nature 347:200-203.
63. Wada, H., and Murata, N. 1990. Temperature-induced changes in the fatty acid composition of the cyanobacterium, Synechocystis PCC6803. Plant Physiol. 92:1062-1069.
64. Weissbach, H., and Brot, N. 1991. Regulation of methionine synthesis in Escherichia coli. Mol. Microbiol. 5:1593-1597.
65. Zhang, Y. X. 1994. Genetic organization of a cluster of genes involved in the production of phaseolotoxin, a phytotoxin produced by Pseudomonas syringae pv. phaseolicola and sequence analysis of the phtE locus. Ph.D. thesis. University of Hawaii, Honolulu, HI.
66. Zhang, Y. X., Rowley, K. B., and Patil, S. S. 1993. Genetic organization of a cluster of genes involved in the production of phaseolotoxin, a phytotoxin produced by Pseudomonas syringae pv. phaseolicola. J. Bacteriol. 175:6451-6458.