Tumor necrosis factor α (TNFα) is cardiodepressant in pathophysiologically relevant concentrations without inducing inducible nitric oxide-(NO)-synthase (iNOS) or triggering serious cytotoxicity

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 11, 1997, Pages 2915-2923

  Müller Werdan, Ursula ^a   Schumann, Heike ^a   Fuchs, Ralph ^b   Reithmann, Christopher ^b   Loppnow, Harald ^a   Koch, Susanne ^a   Zimny Arndt, Ursula ^c   He, Chang ^b   Darmer, Dorothea ^a   Jungblut, Peter ^c   Stadler, Josef ^d   Holtz, Jürgen ^a   Werdan, Karl ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cardiodepression; Cardiomyocytes; Catecholamines; Contractility; Inducible nitric oxide synthase; Tumor necrosis factor

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CALCIUM ION; DEXAMETHASONE; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BLOOD LEVEL; CARDIOMYOPATHY; CARDIOTOXICITY; CELL CULTURE; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; HEART BEAT; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; INOTROPISM; NEWBORN; NONHUMAN; PATHOGENESIS; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0031282192     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0526     Document Type: Article

References (42)

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