Study of microcirculation by coloured microspheres and NMR-microscopy in isolated rat heart: Effect of ischaemia, endothelin-1 and endothelin-1 antagonist BQ 610

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 11, 1997, Pages 3115-3122

  Hiller, Karl Heinz ^b   Roder, Fridtjof ^b   Adami, Peter ^b   Voll, Sabine ^b   Kowallik, Peter ^b   Haase, Axel ^b   Ertl, Georg ^b   Bauer, Wolfgang R ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

Coronary microcirculation; Coronary vessels; Isolated rat heart; Microspheres; NMR; Perfusion; Vasodynamics

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; MICROSPHERE;

ANIMAL TISSUE; ARTICLE; CORONARY BLOOD VESSEL; ENDOCARDIUM; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART VENTRICLE WALL; ISOLATED HEART; MALE; MICROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; RESISTANCE BLOOD VESSEL;

EID: 0031281889     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0538     Document Type: Article

References (14)

1. ANDERSON PG, BISHOP SP, DIGERNESS SB, 1987. Transmural progression of morphologic changes during ischaemic contracture and reperfusion in the normal and hypertrophied rat heart. Am J Pathol 129: 152-167.
2. BAUER WR, HILLER KH, RODER F, NEUBAUER S, FUCHS A, GROßE BOES C, LUTZ R, GAUDRON P, HU K, HAASE A, ERTL G, 1995. Investigation of coronary vessels in microscopic dimensions by two- and three-dimensional NMR-microscopic imaging in the isolated rat heart: visualization of vasoactive effects of endothelin-1. Circulation 92: 968-977.
3. BAUER WR, HILLER KH, RODER F, ROMMEL E, ERTL G, HAASE A, 1996a. Magnetization exchange in capillaries by microcirculation affects diffusion-controlled spin-relaxation: a model which describes the effect of perfusion on relaxation enhancement by intravascular contrast agents. MRM 35: 43-55.
4. BAUER WR, RODER F, HILLER K-H, ERTL G, HAASE A, 1996b. MRI of perfusion using slice selective determination of T1: experiments in isolated rat hearts. Abstract of the 13th Annual Meeting of the European Society of Magnetic Resonance in Medicine and Biology (ESMRMB). MAGMA 4: 137-248.
5. CHILIAN WM, DEFILY DV, 1991. Methological approaches used for the study of coronary microcirculation in situ. Blood Vessels 28: 236-244.
6. HILLER KH, ADAMI P, VOLL S, RODER F, KOWALLIK P, BAUER WR, HAASE A, ERTL G, 1996. In vivo colored microspheres in the isolated rat heart for use in NMR. J Mol Cell Cardiol 28: 571-577.
7. JONES CJH, KUO L, DAVIS MJ, CHILIAN WM, 1996. In vivo and in vitro vasoactive reactions of coronary arteriolar microvessels to nitroglycerine. Am J Physiol 271: H461-H468.
8. KANATSUKA H, LAMPING KG, EASTHAM CL, MARCUS ML, 1990. Heterogeneous changes in epimyocardial microvascular size during graded coronary stenosis: evidence of the microvascular site of autoregulation. Circ Res 66: 389-396.
9. KOWALLIK P, SCHULZ R, GUTH BD, SCHADE A, PAFFHAUSEN W, GROSS R, HEUSCH G, 1991. Measurement of regional myocardial blood flow with multiple coloured microspheres. Circulation 83: 974-982.
10. LAMPING KG, CLOTHIER JL, EASTHAM CL, MARCUS ML, 1992. Coronary microvascular response to endothelin is dependent on vessel diameter and route of administration. Am J Physiol 263: H703-H709.
11. LANGENDORFF O, 1895, Untersuchung am uberlebenden Säugetierherzen. Pflügers Arch 61: 291-332.
12. MAKOWSKI EL, MESCHIA G, DROEGEMUELLER W, BATTAGLIA FC, 1968. Measurement of umbilical arterial blood flow to the sheep placenta and fetus in utero: distribution to cotyledons and the intercotyledonary chorion. Circ Res 23: 623-631.
13. NELLIS SH, LIEDTKE AJ, WHITESELL L, 1981. Small coronary vessel pressure and diameter in an intact beating rabbit heart using fixed-position and free-motion techniques. Circ Res 49: 342-353.
14. YADA T, HIRAMATSU O, KIMURA A, GOTO M, OGASAWARA Y, TSUJIOKA K, YAMAMORI S, OHNO K, HOSAKA H, KAJIYA F, 1993. In vivo observation of subendocardial microvessels of the beating porcine heart using a needle-probe videomicroscope with a CCD camera. Circ Res 72: 939-946.