Inhibitors of cyclic nucleotide phosphodiesterase isozymes block renal tubular cell proliferation induced by folic acid

Journal of Laboratory and Clinical Medicine

Volumn 130, Issue 5, 1997, Pages 487-495

  Matousovic, Karel ^a   Tsuboi, Yasushi ^a   Walker, Henry ^a   Grande, Joseph P ^a   Dousa, Thomas P ^a,b  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031281836     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(97)90125-6     Document Type: Article

References (40)

1. Ryan WL, Heidrick ML. Role of cyclic nucleotides in cancer. In: Greengard P, Robison GA, editors. Advances in cyclic nucleotide research (vol. 4). New York: Raven Press, 1974:81-116.
2. Chlapowski FJ, Kelly LA, Butcher RW. Cyclic nucleotides in cultured cells. In: Greengard P, Robison GA, editors. Advances in cyclic nucleotide research (vol. 6). New York: Raven Press, 1975:245-338.
3. Marx J. Two major signal pathways linked. Science 1993;262:988-9.
4. Graves LM, Bornfeldt KE, Raines EW, et al. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc Natl Acad Sci U S A 1993;90:10300-4.
5. Cano E, Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 1995;20:117-22.
6. Häfner S, Adler HS, Mischak H, et al. Mechanism of inhibition of Raf-1 by protein kinase A. Mol Cell Biol 1994;14:6696-703.
7. Mischak H, Seitz T, Janosch P, et al. Negative regulation of raf-1 by phosphorylation of serine 621. Mol Cell Biol 1996;16:5409-18.
8. Bokemeyer D, Sorokin A, Dunn MJ. Multiple intracellular MAP kinase signaling cascades. Kidney Int 1996;49:1187-98.
9. Huang C-Y, Ferrell JE Jr. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A 1996;93:10078-83.
10. Ferrell JE Jr. Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. Trends Pharmacol Sci 1996;21:460-6.
11. Matousovic K, Grande JP, Chini CCS, Chini EN, Dousa TP. Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells. J Clin Invest 1995;96:401-10.
12. Chini EN, Choi E, Grande JP, Burnett JC, Dousa TP. Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. Biochem Biophys Res Commun 1995;215:868-73.
13. Chini CCS, Grande JP, Chini EN, Dousa TP. Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4: regulation of superoxidation and mitogenesis. J Biol Chem 1997;272:9854-9.
14. Tsuboi Y, Shankland SJ, Grande JP, Walker HJ, Johnson RJ, Dousa TP. Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. J Clin Invest 1996;98:262-70.
15. Tsuboi Y, Shankland SJ, Grande JP, Walker HJ, Johnson RJ, Dousa TP. Antagonist of cAMP phosphodiesterase isozyme PDE-III blocks development of proteinuria, mesangial cells (MC) proliferation and phenotypic transformation in mesangioproliferative glomerulonephritis (MSGN) elicited by anti-thymic serum (ATS) in rats. J Am Soc Nephrol 1996;7:1724.
16. Mené P, Simonson MS, Dunn MJ. Physiology of the mesangial cell. Physiol Rev 1989;69:1347-424.
17. Threlfall G. Cell proliferation in the rat kidney induced by folic acid. Cell Tissue Kinet 1968;1:383-92.
18. Baserga R, Thatcher D, Marzi D. Cell proliferation in mouse kidney after a single injection of folic acid. Lab Invest 1968;19:92-6.
19. Threlfall G. Nucleic acid synthesis and cell proliferation in folic acid-induced renal hypertrophy. In: Nowinski WW, Goss RJ, editors. Compensatory renal hypertrophy. New York: Academic Press, 1969:157-82.
20. Byrnes KA, Ghidoni JJ, Suzuki M, Thomas H, Mayfield ED Jr. Response of the rat kidney to folic acid administration. II. Morphologic studies. Lab Invest 1972;26:191-200.
21. Cowley BD Jr, Chadwick LJ, Grantham JJ, Calvet J. Sequential protooncogene expression in regenerating kidney following acute renal injury. J Biol Chem 1989;264:8389-93.
22. Calvet JP, Chadwick LJ. Primary and secondary genetic responses after folic acid-induced acute renal injury in the mouse. J Am Soc Nephrol 1994;5:1324-32.
23. Cowley BD Jr, Gudapaty S. Temporal alterations in regional gene expression after nephrotoxic renal injury. J Lab Clin Med 1995;125:187-99.
24. Asselin C, Marcu KB. Mode of c-myc gene regulation in folic acid-induced kidney regeneration. Onocogene Res 1989;5:67-72.
25. Kujubu DA, Norman JT, Herschman HR, Fine LG. Primary response gene expression in renal hypertrophy and hyperplasia: evidence for different growth initiation processes. Am J Physiol (Renal Fluid Electrolyte Physiol 29) 1991;260:F823-7.
26. Alberti P, Bardella L, Comolli R. Ribosomal protein S6 kinase is activated after folic acid injury and epidermal growth factor administration but not after unilateral nephrectomy in the rat kidney. Nephron 1992;60:330-5.
27. Miltenberger RJ, Cortner J, Farnham PJ. An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes. J Biol Chem 1993;268:15674-80.
28. Rankin CA, Grantham JJ, Calvet JP. C-Fos expression is hypersensitive to serum-stimulation in cultured cystic kidney cells from the C57BL/6J-cpk mouse. J Cell Physiol 1992;152:578-86.
29. Hinrichs HR, Petersen RO, Baserga R. Incorporation of thymidine into DNA of mouse organs. Arch Pathol 1964;78:245-53.
30. Byrnes KA, Ghidoni JJ, Mayfield ED Jr. Response of the rat kidney to folic acid administration. Lab Invest 1972;26:184-90.
31. Burdon RH, van Knippenberg PH, editors. Laboratory techniques in biochemistry and molecular biology. New York: Elsevier, 1990:333-4.
32. Radford MG Jr, Donadio JV Jr, Bergstralh EJ, Grande JP. Predicting renal outcome in IgA nephropathy. J Am Soc Nephrol 1997;8:199-207.
33. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
34. Shah SV, Northrup TE, Hui YSF, Dousa TP. Action of serotonin (5-hydroxytryptamine) on cyclic nucleotides in glomeruli of rat renal cortex. Kidney Int 1979;15:463-72.
35. Abboud HE, Ou SL, Velosa JA, Shah SV, Dousa TP. Dynamics of renal histamine in normal rat kidney and in nephrosis induced by aminonucleoside of puromycin. J Clin Invest 1982;69:327-36.
36. Chini CCS, Chini EN, Willliams JM, Matousovic K, Dousa TP. Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IV. Kidney Int 1994;46:28-36.
37. Beavo JA. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 1995;75:725-48.
38. Burns F, Zhao AZ, Beavo JA. Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications. Adv Pharmacol 1996;36:29-48.
39. Manganiello VC, Murata T, Taira M, Belfrage P, Degerman E. Perspectives in biochemistry and biophysics: diversity in cyclic nucleotide phosphodiesterase isozyme families. Arch Biochem Biophys 1995;322:1-13.
40. Conti M, Nemoz G, Sette C, Vincini E. Recent progress in understanding the hormonal regulation of phosphodiesterases. Endocr Rev 1995;16:370-89.