Ferritin Expression after in Vitro Exposures of Human Alveolar Macrophages to Silica Is Iron-dependent

American Journal of Respiratory Cell and Molecular Biology

Volumn 17, Issue 5, 1997, Pages 533-540

  Ghio, Andrew J ^a   Carter, Jacqueline D ^b   Samet, James M ^b   Quay, Jacqueline ^b   Wortman, Ivo A ^b   Richards, Judy H ^b   Kennedy, Thomas P ^b   Devlin, Robert B ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; IRON; SILICON DIOXIDE;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; HUMAN; LUNG ALVEOLUS MACROPHAGE; METABOLISM;

CELLS, CULTURED; FERRITINS; HUMANS; IRON; MACROPHAGES, ALVEOLAR; SILICON DIOXIDE;

EID: 0031279395     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.17.5.2791     Document Type: Article

References (35)

1. Schindler, P. W., and W. Stumm. 1987. The surface chemistry of oxides, hydroxides, and oxide minerals. In Aquatic Surface Chemistry: Chemical Processes at the Particle-Water Interface. W. Stumm, editor. John Wiley & Sons, New York. 83-110.
2. Herrara, R., and M. Peech. 1970. Reaction of montmorillonite with iron (III). Soil Sci Sec. Am. Proc. 34:740-745.
3. Stumm, W., and J. J. Morgan. 1981. Aquatic Chemistry: An Introduction Emphasizing Chemical Equilibria in Natural Waters. John Wiley & Sons, New York. 599-684.
4. Ghio, A. J., T. P. Kennedy, A. R. Whorton, A. L. Crumbliss, G. E. Hatch, and J. R. Hoidal. 1992. The role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. Am. J. Physiol, 263: L511-L518.
5. Schapira, R. M., A. J. Ghio, R. M. Effros, J. Morrisey, C. A. Dawson, and A. D. Hacker. 1994. Hydroxyl radicals are formed in the rat lung following asbestos instillation in vivo. Am. J. Respir. Cell Mol. Biol. 10:573-579.
6. Ghio, A. J., R. H. Jaskot, and G. E. Hatch. 1994. Collagen deposition after intratracheal instillation of silica is associated with an accumulation of non-heme iron in the rat lung. Am. J. Physiol. 267:L686-L692.
7. Olakanmi, O., S. E. McGowan, M. B. Hayek, and B. E. Britigan. 1993. Iron sequestration by macrophages decreases the potential for extracellular hydroxyl radical formation. J. Clin. Invest. 91:889-899.
8. Cozzi, A., P. Santambrogio, S. Levi, and P. Arosio. 1990. Iron detoxifying activity of ferritin: effects of H and L human apoferritins on lipid peroxidation in vitro. FEBS Lett. 277:119-122.
9. Balla, G., H. S. Jacob, J. Balla, M. Rosenberg, K. Nath, F. Apple, J. W. Eaton, and G. M. Vercellotti. 1992. Ferritin: a cytoprotective antioxidant strategem of endothelium. J. Biol. Chem. 267:18148-18153.
10. Balla, J., D. A. Nath, G. Balla, M. B. Juckett, H. S. Jacob, and G. M. Vercellotti. 1995. Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo. Am. J. Physiol. 268:L321-L327.
11. Leibold, E. A., and H. N. Munro. 1988. Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5′ untranslated region of ferritin heavy-and light-subunit mRNAs. Proc. Natl. Acad. Sci. USA 85:2171-2175.
12. Rouault, T. A., M. W. Hentze, S. Wright-Caughman, J. B. Harford, and R. D. Klausner. 1988. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science 241:1207-1210.
13. Kaptain, S., W. E. Downey, C. Tang, C. Philpott, D. Haile, D. G. Orloff, J. B. Harford, T. A. Rouault, and R. D. Klausner. 1991. A regulated RNA binding protein also possesses aconitase activity. Proc. Natl. Acad. Sci. USA 88:10109-10113.
14. Haile, D. J., T. A. Rouault, J. B. Harford, M. C. Kennedy, G. A. Blondin, H. Beinert, and R. D. Klausner. 1992. Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding. Proc. Natl. Acad. Sci. USA 89:11735-11739.
15. Kennedy, M. C., L. Mende-Mueller, G. A. Blondin, and H. Beinert. 1992. Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein. Proc. Natl. Acad. Sci. USA 89:11730-11734.
16. Beinert, H., and M. C. Kennedy. 1993. Aconitase, a two-faced protein: enzyme and iron regulatory factor. FASEB J. 7:1442-1449.
17. Basilion, J. P., T. A. Rouault, C. M. Massinople, R. D. Klausner, and W. H. Burgess. 1994. The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft. Proc. Natl. Acad. Sci. USA 91:574-578.
18. Suzuki, Y., and J. Churg. 1970. Formation of the asbestos body: a comparative study with three types of asbestos. Environ. Res. 3:107-118.
19. Colton, T. 1974. Statistics in Medicine. Little, Brown, Boston.
20. Sibille, J.-C., H. Kondo, and P. Aisen. 1988. Interactions between isolated hepatocytes and kupffer cells in iron metabolism: a possible role for ferritin as an iron carrier protein. Hepatology 8:296-301.
21. Wesselius, L. J., M. E. Nelson, and B. S. Skikne. 1994. Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokers. Am. J. Respir. Crit. Care Med. 150:690-695.
22. McGahan, M. C., J. Harned, A. M. Crimes, and L. N. Fleisher. 1994. Regulation of ferritin levels in cultured lens epithelial cells. Exp. Eye Res. 59: 551-555.
23. Lobreaux, S., S. Thoiron, and J.-F. Briat. 1995. Induction of ferritin synthesis in maize leaves by an iron-mediated oxidative stress. Plant J. 8:443-449.
24. Sato, H., M. Yamaguchi, and S. Bannai. 1994. Regulation of ferritin synthesis in macrophages by oxygen and a sulfhydryl-reactive agent. Biochem. Biophys. Res. Commun. 201:38-44.
25. 3+ from surface of asbestos. Arch. Biochem. Biophys. 315:219-225.
26. Koerten, H. K., P. Brederoo, L. A. Ginsel, and W. T. Daems. 1986. The endocytosis of asbestos by mouse peritoneal macrophages and its long term effect on iron accumulation with labyrinth formation. Eur. J. Cell. Biol. 40:25-36.
27. Vorwald, A. J., T. M. Durkan, and P. C. Pratt. 1951. Experimental studies of asbestosis. Arch. Ind. Hyg. Occup. Med. 3:1-4.
28. MeLemore, T. L., M. L. Mace, V. Roggli, M. V. Marshall, E. C. Lawrence, R. K. Wilson, R. R. Martin, B. R. Brinkley, and S. D. Greenberg, 1980. Asbestos body phagocytosis by human free alveolar macrophages. Cancer Lett. 9:85-93.
29. Custer, G., S. Balcerzak, and J. Rinehart. 1982. Human macrophage hemoglobin-iron metabolism in vitro. Am. J. Hematol. 13:23-26.
30. Saito, K., T. Nishisato, and J. A. Grasso. 1986. Interaction of transferrin with iron-loaded rat peritoneal macrophages. Br. J. Haematol. 62:275-286.
31. Wesselius, L. J., C. H. Flowers, and B. S. Skikne. 1992. Alveolar macrophage content of isoferritin and transferrin: comparison of nonsmokers and smokers with and without chronic airflow obstruction. Am. Rev. Respir. Dis. 145:311-316.
32. Iancu, I. C., L. Lichterman, and M. B. Neustein. 1978. Hepatic sinusoidal cells in iron overload. J. Med. Sci. 14:1191-1201.
33. Torti, S. V., and F. M. Torti. 1994. Iron and ferritin in inflammation and cancer. Adv. Inorg. Biochem. 10:119-137.
34. Brown, A. L., S. Yamaguchi, and J. Leal-Diaz. 1965. Evidence of translocation of iron in plants. Plant Physiol. 40 (Suppl.):35-38.
35. Zhang, C., V. Romheld, and H. Marschner. 1995. Retranslocation of iron from primary leaves of bean plants grown under iron deficiency. J. Plant Physiol. 146:268-272.