Stromal Cell Modulation of Negative Regulatory Signals That Influence Apoptosis and Proliferation of B Lineage Lymphocytes

Journal of Immunology

Volumn 159, Issue 9, 1997, Pages 4171-4179

  Borghesi, Lisa A ^a   Smithson, Glennda ^a   Kincade, Paul W ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE;

ANIMAL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; BONE MARROW CELL; CELL CULTURE; CELL DIVISION; CELL LINEAGE; COCULTURE; CYTOLOGY; FEMALE; IMMUNOLOGY; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; STROMA CELL;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; BONE MARROW CELLS; CELL ADHESION MOLECULES; CELL DIVISION; CELL LINEAGE; CELLS, CULTURED; COCULTURE TECHNIQUES; FEMALE; MICE; MICE, INBRED BALB C; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 0031279146     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Fairbairn, L., G. Cowling, B. Reipert, and T. Dexter. 1993. Suppression of apoptosis allows differentiation and development of a multipotential hemopoietic cell line in the absence of added growth factors. Cell 74:823.
2. Osmond, D., S. Rico-Vargas, H. Valenzona, L. Fauteux, L. Liu, R. Janani, L. Lu, and K. Jacobsen. 1994. Apoptosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow. Immunol. Rev. 142:209.
3. Löffert, D., S. Schaal, A. Ehlich, R. R. Hardy, Y.-R. Zou, W. Müller, and K. Rajewsky. 1994. Early B-cell development in the mouse: insights from mutations introduced by gene targeting. Immunol. Rev. 137:135.
4. Ehlich, A., S. Schaal, H. Gu, D. Kitamura, W. Muller, and K. Rajewsky. 1993. Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell 72:695.
5. Chang, Y., G. C. Bosma, and M. J. Bosma. 1995. Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination. Immunity 2:607.
6. Spanopoulou, E., C. A. Roman, L. M. Corcoran, M. S. Schlissel, D. P. Silver, D. Nemazee, M. C. Nussenzweig, S. A. Shinton, R. R. Hardy, and D. Baltimore. 1994. Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes Dev. 8:1030.
7. Young, F., B. Ardman, Y. Shinkai, R. Lansford, K. T. Blackwell, M. Mendelsohn, A. Rolink, F. Melchers, and F. W. Alt. 1994. Influence of immunoglobulin heavy-and light-chain expression on B-cell differentiation. Genes Dev. 8:1043.
8. Jacobsen, K., and D. G. Osmond. 1990. Microenvironmental organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow. Eur. J. Immunol. 20:2395.
9. Miyake, K., K. Medina, K. Ishihara, M. Kimoto, R. Auerbach, and P. W. Kincade. 1991. A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture. J. Cell Biol. 114:557.
10. Jacobsen, K., J. Kravitz, P. W. Kincade, and D. G. Osmond. 1996. Adhesion receptors on bone marrow stromal cells: in vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and γ-irradiated mice. Blood 87:73.
11. Miyake, K., K. L. Medina, S.-I. Hayashi, S. Ono, T. Hamaoka, and P. W. Kincade. 1990. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. J. Exp. Med. 171:477.
12. Koopman, G., R. M. Keehnen, E. Lindhout, W. Newman, Y. Shimizu, G. A. van Seventer, C. de Groot, and S. T. Pals. 1994. Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. J. Immunol. 152:3760.
13. Kierney, P. C., and K. Dorshkind. 1987. B lymphocyte precursors and myeloid progenitors survive in diffusion chamber cultures but B cell differentiation requires close association with stromal cells. Blood 70:1418.
14. Sudo, T., M. Ito, Y. Ogawa, M. Iizuka, H. Kodama, T. Kinisada, S.-I. Hayashi, M. Ogawa, K. Sakai, S. Nishikawa, and S.-I. Nishikawa. 1989. Interleukin 7 production and function in stromal cell-dependent B cell development. J. Exp. Med. 170:333.
15. Ray, R. J., C. Furlonger, D. E. Williams, and C. J. Paige. 1996. Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro. Eur. J. Immunol. 26:10.
16. Witte, P. L., L. M. Franstve, M. Hergott, and S. M. Rahbe. 1993. Cytokine production and heterogeneity of primary stromal cells that support B lymphopoiesis. Eur. J. Immunol. 23:1809.
17. Lisovsky, M., S. Braun, Y Ge, H. Takahira, L. Lu, V. Savchenko, S. Lyman, and H. Broxmeyer. 1996. Flt3-ligand production by human bone marrow stromal cells. Leukemia 10:1012.
18. Nagasawa, T., H. Kikutani, and T. Kishimoto. 1994. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl Acad. Sci. USA 91: 2305.
19. Landreth, K. S., R. Narayanan, and K. Dorshkind. 1992. Insulin-like growth factor-I regulates pro-B cell differentiation. Blood 80:1207.
20. Namikawa, R., M. O. Muench, J. E. de Vries, and M.-G. Roncarolo. 1996. The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro. Blood 87:1881.
21. Ray, R. I., C. J. Paige, C. Furlonger, S. D. Lyman, and R. Rottapel. 1996. Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7. Eur. J. Immunol. 26:1504.
22. Rolink, A., M. Streb, and S.-I. Nishikawa. 1991. The c-kit-encoded tyrosine kinase regulates the proliferation of early pre-B cells. Eur. J. Immunol. 21:2609.
23. Hirayama, F., S. C. Clark, and M. Ogawa. 1994. Negative regulation of early B lymphopoiesis by interleukin 3 and interleukin 1α. Proc. Natl. Acad. Sci. USA 91:469.
24. Fauteux, L. J., and D. G. Osmond. 1996. IL-1 as a systemic modifier of B lymphopoiesis. J. Immunol. 156:2376.
25. Wang, J., Q. Lin, H. Langston, and M. D. Cooper. 1995. Resident bone marrow macrophages produce type 1 interferons that can selectively inhibit interleukin-7-driven growth of B lineage cells. Immunity 3:475.
26. 2 induces apoptosis in immature normal and malignant B cells. Clin. Immunol. Immunopathol. 63:221.
27. Smithson, G., K. Medina, I. Ponting, and P. W. Kincade. 1995. Estrogen suppresses stromal cell dependent lymphopoiesis in culture. J. Immunol. 155:3409.
28. Ogawa, M., S. Nishikawa, K. Ikuta, F. Yamamura, M. Naito, K. Takahashi, and S.-I. Nishikawa. 1988. B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST2: B cell progenitor develops first in the embryonal body rather than in the yolk sac. EMBO J. 7:1337.
29. Kodama, H.-A., Y. Amagai, H. Koyama, and S. Kasai. 1982. Hormonal responsiveness of a preadipose line derived from newborn mouse calvaria. J. Cell. Physiol. 112:83.
30. Pietrangeli, C. E., S.-I. Hayashi, and P. W. Kincade. 1988. Stromal cell lines which support lymphocyte growth: characterization, sensitivity to radiation and responsiveness to growth factors. Eur. J. Immunol. 18:863.
31. Kincade, P., K. Medina, C. Pietrangeli, S.-I. Hayashi, and A. Namen. 1991. Stromal cell lines which support lymphocyte growth II. Characteristics of a suppressive subclone. In Mechanisms of Lymphocyte Activation and Immune Regulation III. S. Gupta, ed. Plenum Press, New York, p. 227.
32. Glimcher, L., A. Kruisbeek, W. Paul, and I. Green. 1983. Functional activity of a transformed thymic epithelial cell line. Scand. J. Immunol. 17:1.
33. Lee, G., A. E. Namen, S. Sillis, L. R. Ellingsworth, and P. W. Kincade. 1989. Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-β. J. Immunol. 142:3875.
34. Garvy, B., W. Telford, L. King, and P. Fraker. 1993. Glucocorticoid and irradiation-induced apoptosis in normal murine bone marrow B-lineage lymphocytes as determined by flow cytometry. Immunology 79:270.
35. Oritani, K., X. Wu, K. Medina, J. Hudson, K. Miyake, J. M. Gimble, S. A. Burstein, and P. W. Kincade. 1996. Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures. Blood 87:2252.
36. Koopman, G., C. Reutelingsperger, G. Kuijten, R. Keehnen, and M. van Oers. 1994. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415.
37. Telford, W., L. King, and P. Fraker. 1991. Evaluation of glucocorticoid-induced DNA fragmentation in mouse thymocytes by flow cytometry. Cell Prolif. 24:447.
38. Kishimoto, H., C. D. Suth, and J. C. Sprent. 1995. Upregulation of surface markers on dying thymocytes. J. Exp. Med. 181:649.
39. Funk, P. E., R. P. Stephan, and P. L. Witte. 1995. Vascular cell adhesion molecule 1-positive reticular cells express interleukin-7 and stem cell factor in the bone marrow. Blood 86:2661.
40. Miyake, K., I. L. Weissman, J. Greenberger, and P. W. Kincade. 1991. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J. Exp. Med. 173:599.
41. Jarvis, L. J., and T. W. LeBien. 1995. Stimulation of human bone marrow stromal cell tyrosine kinases and IL-6 production by contact with B lymphocytes. J. Immunol. 155:2359.
42. Oritani, K., and P. W. Kincade. 1996. Identification of stromal cell products that interact with pre-B cells. J. Cell Biol. 134:771.
43. Clarke, D., O. Katoh, R. Gibbs, S. Griffiths, and M. Gordon. 1995. Interaction of interleukin 7 (IL-7) with glycosaminoglycans and its biological relevance. Cytokine 7:325.
44. Roberts, R., J. Gallagher, E. Spooncer, T. Allen, F. Bloomfield, and T. Dexter. 1988. Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis. Nature 332:376.
45. Gordon, M. Y., G. P. Riley, S. M. Watt, and M. F. Greaves. 1987. Compartmentalization of a haemopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment. Nature 326:403.
46. Kincade, P. W., K. Medina, G. Smithson, Z. Zheng, K. Oritani, L. Borghesi, Y. Yamashita, K. Payne, and T. Shimozato. Life/death decisions in B lymphocyte precursors: a role for cytokines, cell interaction molecules and hormones. In Molecular Biology of B and T Cell Development. J. G. Monroe and E. V. Rothenberg, eds. Humana Press, Totowa, NJ. In press.
47. Dorshkind, K. 1988. Interleukin-1 inhibition of B lymphopoiesis is reversible. Blood 72:2053.
48. Dorshkind, K. 1988. IL-1 inhibits B cell differentiation in long term bone marrow cultures. J. Immunol. 141:531.
49. Suda, T., S. Okada, J. Suda, Y. Miura, M. Ito, T. Sudo, S.-I. Hayashi, S.-I. Nishikawa, and H. Nakauchi. 1989. A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and inhibitory effect of IL-1α. Blood 74:1936.
50. Merino, R., L. Ding, D. J. Veis, S. J. Korsmeyer, and G. Nuñez. 1994. Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J. 13:683.
51. Gibson, L. F., D. Piktel, R. Narayanan, G. Nuñez, and K. S. Landreth. 1996. Stromal cells regulate bcl-2 and bax expression in pro-B cells. Exp. Hematol. 24:628.
52. King, L. B., M. S. Vacchio, K. Dixon, R. Hunziker, D. Margulies, and J. Ashwell. 1995. A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development. Immunity 3:647.
53. Amarante-Mendes, J., R. Chammas, P. Abrahamsohn, P. Patel, E. Potworowski, and M. Macedo. 1995. Cloning of a thymic stromal cell capable of protecting thymocytes from apoptosis. Cell. Immunol. 161:173.
54. Lu, L., and D. G. Osmond. 1997. Apoptosis during B lymphopoiesis in mouse bone marrow. J. Immunol. 158:5136.
55. Manabe, A., E. Coustan-Smith, F. G. Behm. S. C. Raimondi, and D. Campana. 1992. Bone marrow-derived stromal cells prevent apoptotic cell death in B-lineage acute lymphoblastic leukemia. Blood 79:2370.
56. Manabe, A., G. K. Murti, E. Coustan-Smith, M.-A. Kumagai, F. G. Behm, S. C. Raimondi, and D. Campana. 1994. Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells. Blood 83: 758.