Ca2+ dependence and pharmacology of large-conductance K+ channels in nonlabor and labor human uterine myocytes

American Journal of Physiology - Cell Physiology

Volumn 273, Issue 5 42-5, 1997, Pages

  Khan, Raheela N ^a,d   Smith, Stephen K ^a   Morrison, J J ^a,c   Ashford, Michael L J ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Ball peptide; Barium; Calcium activated potassium channels; Charybdotoxin; Human myometrium; Potassium channel blockers; Pregnancy; Tetraethylammonium

Indexed keywords

CALCIUM; POTASSIUM; POTASSIUM CHANNEL; 4 AMINOPYRIDINE; BARIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; TETRYLAMMONIUM;

ARTICLE; CALCIUM CONDUCTANCE; CHANNEL GATING; FEMALE; HUMAN; HUMAN TISSUE; LABOR; MYOMETRIUM; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY; CELL CULTURE; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; DRUG EFFECT; PATCH CLAMP; PHYSIOLOGY; PREGNANCY; REFERENCE VALUE; SMOOTH MUSCLE;

4-AMINOPYRIDINE; BARIUM; CALCIUM; CELLS, CULTURED; CHARYBDOTOXIN; FEMALE; HUMANS; ION CHANNEL GATING; LABOR, OBSTETRIC; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE POTENTIALS; MUSCLE, SMOOTH; MYOMETRIUM; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PREGNANCY; REFERENCE VALUES; TETRAETHYLAMMONIUM;

EID: 0031278783     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.273.5.c1721     Document Type: Article

References (30)

1. + channels in pregnant rat myometrium: modulation by a β-adrenergic agent. Am. J. Physiol. 263 (Cell Physiol. 32): C1049-C1056, 1992.
2. + channels in arterial and intestinal smooth muscle cell membranes. Pflügers Arch. 403: 120-127, 1985.
3. Blatz, A. L., and K. L. Magleby. Ion conductance and selectivity of single calcium-activated potassium channels in cultured rat skeletal muscle. J. Gen. Physiol. 84: 1-23, 1984.
4. + channel modulated by a functionally associated protein kinase. Nature 369: 563-565, 1994.
5. Farley, J., and B. Rudy. Multiple types of voltage-dependent Ca-activated potassium channels of large conductance in rat brain synaptosomal membranes. Biophys. J. 53: 919-934, 1988.
6. + channels. Neuron 9: 229-236, 1992.
7. +-channel activity in bovine isolated tracheal smooth muscle cells. Br. J. Pharmacol. 102: 871-878, 1991.
8. + channels in human myometrium during pregnancy and labor. Proc. R. Soc. Lond. B 251: 9-15, 1993.
9. Kihira, M., K. Matsuzawa, H. Tokuno, and T. Tomita. Effects of calmodulin antagonists on calcium-activated potassium channels in pregnant rat myometrium. Br. J. Pharmacol. 100: 353-359, 1990.
10. Kirsch, G. E., and J. A. Drewe. Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels. J. Gen. Physiol. 102: 797-816, 1993.
11. + channel from smooth muscle. J. Biol. Chem. 269: 17274-17278, 1994.
12. Langton, P. D., M. T. Nelson, Y. Huang, and N. B. Standen. Block of calcium-activated potassium channels in mammalian arterial myocytes by tetraethylammonium ions. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H927-H934, 1991.
13. Latorre, R., A. Oberhauser, P. Labarca, and O. Alvarez. Varieties of calcium-activated potassium channels. Annu. Rev. Physiol. 51: 385-399, 1989.
14. + channel present in rat cortical neurones. J. Physiol. (Land.) 488: 319-337, 1995.
15. McCann, J. D., and M. J. Welsh. Calcium-activated potassium channels in canine airway smooth muscle. J. Physiol. (Lond.) 372: 113-127, 1986.
16. McManus, O. B., L. M. H. Helms, L. Pallanck, B. Ganetzky, R. Swanson, and R. J. Leonard. Functional role of the β-subunit of high conductance calcium-activated potassium channels. Neuron 14: 645-650, 1995.
17. + channel. J. Gen. Physiol. 90: 427-449, 1987.
18. Mirroneau, J., and J. P. Savineau. Effects of calcium ions on outward currents in rat uterine smooth muscle. J. Physiol. (Lond.) 302: 411-425, 1980.
19. ca channels by PKA in pregnant and nonpregnant myometrium. Am. J. Physiol. 266 (Cell Physiol. 35): C1459-C1463, 1994.
20. Piedras-Renteria, E., E. Stefani, and L. Toro. Potassium currents in freshly dispersed myometrial cells. Am. J. Physiol. 261 (Cell Physiol. 30): C278-C284, 1991.
21. Smart, T. G. Single calcium-activated potassium channels recorded from cultured rat sympathetic neurones. J. Physiol. (Lond.) 389: 337-360, 1987.
22. ca channels incorporated into lipid bilayers. J. Gen. Physiol. 96: 373-394, 1990.
23. + channel by Shaker B inactivating ball peptide. Neuron 9: 237-245, 1992.
24. Tritthart, H. A., W. Mahnert, W., A. Fleischhacker, and N. Adelwohrer. Potassium channels and modulating factors of channel functions in the human myometrium. Z. Kardiol. 80: 29-33, 1991.
25. 2+ blockade. J. Gen. Physiol. 82: 543-568, 1983.
26. + channel with quaternary ammonium ions. Pflügers Arch. 413: 118-126, 1988.
27. + channels of high conductance in smooth muscle cells from rat cerebral arteries. J. Physiol. (Lond.) 462: 529-545, 1993.
28. Wong, B. S., and M. Adler. Tetraethylammonium blockade of calcium-activated potassium channels in clonal anterior pituitary cells. PflÜgers Arch. 407: 279-284, 1986.
29. Woodhull, A. M. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61: 687-708, 1973.
30. + channels of bovine chromaffin cells. J. Gen. Physiol. 84: 157-186, 1984.